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Journal Abstract Search

174 related items for PubMed ID: 8391116

  • 1. Effect of pH on DNA alkylation by enzyme-activated mitomycin C and porfiromycin.
    Yu F, Pan SS.
    Mol Pharmacol; 1993 Jun; 43(6):863-9. PubMed ID: 8391116
    [Abstract] [Full Text] [Related]

  • 2. Enzymatic and pH modulation of mitomycin C-induced DNA damage in mitomycin C-resistant HCT 116 human colon cancer cells.
    Pan SS, Yu F, Hipsher C.
    Mol Pharmacol; 1993 Jun; 43(6):870-7. PubMed ID: 8316219
    [Abstract] [Full Text] [Related]

  • 3. DNA alkylation by enzyme-activated mitomycin C.
    Pan SS, Iracki T, Bachur NR.
    Mol Pharmacol; 1986 Jun; 29(6):622-8. PubMed ID: 3086708
    [Abstract] [Full Text] [Related]

  • 4. Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C.
    Suresh Kumar G, Lipman R, Cummings J, Tomasz M.
    Biochemistry; 1997 Nov 18; 36(46):14128-36. PubMed ID: 9369485
    [Abstract] [Full Text] [Related]

  • 5. Metabolites and DNA adduct formation from flavoenzyme-activated porfiromycin.
    Pan SS, Iracki T.
    Mol Pharmacol; 1988 Aug 18; 34(2):223-8. PubMed ID: 3412325
    [Abstract] [Full Text] [Related]

  • 6. Adducts of mitomycin C and DNA in EMT6 mouse mammary tumor cells: effects of hypoxia and dicumarol on adduct patterns.
    Bizanek R, Chowdary D, Arai H, Kasai M, Hughes CS, Sartorelli AC, Rockwell S, Tomasz M.
    Cancer Res; 1993 Nov 01; 53(21):5127-34. PubMed ID: 7693331
    [Abstract] [Full Text] [Related]

  • 7. Detection of mitomycin C-DNA adducts in human breast cancer cells grown in culture, as xenografted tumors in nude mice, and in biopsies of human breast cancer patient tumors as determined by (32)P-postlabeling.
    Warren AJ, Mustra DJ, Hamilton JW.
    Clin Cancer Res; 2001 Apr 01; 7(4):1033-42. PubMed ID: 11309355
    [Abstract] [Full Text] [Related]

  • 8. Syntheses of DNA adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC) and 2-amino-9H-pyrido[2,3-b]indole (AalphaC) and identification of DNA adducts in organs from rats dosed with MeAalphaC.
    Frederiksen H, Frandsen H, Pfau W.
    Carcinogenesis; 2004 Aug 01; 25(8):1525-33. PubMed ID: 15059926
    [Abstract] [Full Text] [Related]

  • 9. Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C.
    Palom Y, Belcourt MF, Kumar GS, Arai H, Kasai M, Sartorelli AC, Rockwell S, Tomasz M.
    Oncol Res; 1998 Aug 01; 10(10):509-21. PubMed ID: 10338154
    [Abstract] [Full Text] [Related]

  • 10. Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation.
    Maliepaard M, de Mol NJ, Tomasz M, Gargiulo D, Janssen LH, van Duynhoven JP, van Velzen EJ, Verboom W, Reinhoudt DN.
    Biochemistry; 1997 Jul 29; 36(30):9211-20. PubMed ID: 9230054
    [Abstract] [Full Text] [Related]

  • 11. Tumor-specific synergistic therapy of mitomycin C: modulation of bioreductive activation.
    Sakamoto N, Toge T, Nishiyama M.
    Hiroshima J Med Sci; 1997 Jun 29; 46(2):67-73. PubMed ID: 9232934
    [Abstract] [Full Text] [Related]

  • 12. Development of methods for measuring biological markers of formaldehyde exposure.
    Fennell TR.
    Res Rep Health Eff Inst; 1994 Jun 29; (67):1-20; discussion 21-6. PubMed ID: 7917119
    [Abstract] [Full Text] [Related]

  • 13. Detection of mitomycin C-DNA adducts in vivo by 32P-postlabeling: time course for formation and removal of adducts and biochemical modulation.
    Warren AJ, Maccubbin AE, Hamilton JW.
    Cancer Res; 1998 Feb 01; 58(3):453-61. PubMed ID: 9458089
    [Abstract] [Full Text] [Related]

  • 14. pH-dependent inactivation of DT-diaphorase by mitomycin C and porfiromycin.
    Siegel D, Beall H, Kasai M, Arai H, Gibson NW, Ross D.
    Mol Pharmacol; 1993 Dec 01; 44(6):1128-34. PubMed ID: 8264549
    [Abstract] [Full Text] [Related]

  • 15. The role of NAD(P)H:quinone oxidoreductase in mitomycin C- and porfiromycin-resistant HCT 116 human colon-cancer cells.
    Pan SS, Akman SA, Forrest GL, Hipsher C, Johnson R.
    Cancer Chemother Pharmacol; 1992 Dec 01; 31(1):23-31. PubMed ID: 1458556
    [Abstract] [Full Text] [Related]

  • 16. 32P-Postlabeling analysis of DNA adducts of styrene 7,8-oxide at the O6-position of guanine.
    Otteneder M, Eder E, Lutz WK.
    Chem Res Toxicol; 1999 Jan 01; 12(1):93-9. PubMed ID: 9894023
    [Abstract] [Full Text] [Related]

  • 17. Reductive alkylation of DNA by mitomycin A, a mitomycin with high redox potential.
    McGuinness BF, Lipman R, Goldstein J, Nakanishi K, Tomasz M.
    Biochemistry; 1991 Jul 02; 30(26):6444-53. PubMed ID: 1905153
    [Abstract] [Full Text] [Related]

  • 18. Reductive activation of mitomycin C by thiols: kinetics, mechanism, and biological implications.
    Paz MM.
    Chem Res Toxicol; 2009 Oct 02; 22(10):1663-8. PubMed ID: 19791750
    [Abstract] [Full Text] [Related]

  • 19. A mitomycin-N6-deoxyadenosine adduct isolated from DNA.
    Palom Y, Lipman R, Musser SM, Tomasz M.
    Chem Res Toxicol; 1998 Mar 02; 11(3):203-10. PubMed ID: 9544618
    [Abstract] [Full Text] [Related]

  • 20. Reaction of DNA with chemically or enzymatically activated mitomycin C: isolation and structure of the major covalent adduct.
    Tomasz M, Chowdary D, Lipman R, Shimotakahara S, Veiro D, Walker V, Verdine GL.
    Proc Natl Acad Sci U S A; 1986 Sep 02; 83(18):6702-6. PubMed ID: 3018744
    [Abstract] [Full Text] [Related]

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