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Journal Abstract Search

162 related items for PubMed ID: 8391460

  • 1. The kappa-opioid receptor agonist, U50,488H, exerts antidystonic activity in a mutant hamster model of generalized dystonia.
    Richter A, Löscher W.
    Eur J Pharmacol; 1993 May 19; 236(2):289-94. PubMed ID: 8391460
    [Abstract] [Full Text] [Related]

  • 2. Behavioural effect of pretreatment with opioid antagonists and sigma binding site ligands on the abnormal motor response produced by the kappa opioid agonist U50,488H in guinea pigs.
    Brent PJ.
    Neuropharmacology; 1993 Aug 19; 32(8):751-60. PubMed ID: 8413839
    [Abstract] [Full Text] [Related]

  • 3. The kappa-opioid receptor agonist U50,488H induces acute physical dependence in guinea-pigs.
    Brent PJ, Chahl LA, Cantarell PA, Kavanagh C.
    Eur J Pharmacol; 1993 Sep 14; 241(2-3):149-56. PubMed ID: 7902288
    [Abstract] [Full Text] [Related]

  • 4. Effects of U50,488H on locomotor activity in the hamster.
    Schnur P, Walker JM.
    Pharmacol Biochem Behav; 1990 Aug 14; 36(4):813-6. PubMed ID: 2170998
    [Abstract] [Full Text] [Related]

  • 5. Agonist-induced desensitization and down-regulation of the human kappa opioid receptor expressed in Chinese hamster ovary cells.
    Zhu J, Luo LY, Mao GF, Ashby B, Liu-Chen LY.
    J Pharmacol Exp Ther; 1998 Apr 14; 285(1):28-36. PubMed ID: 9535991
    [Abstract] [Full Text] [Related]

  • 6. Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPgammaS binding to membranes: determination of potencies and efficacies of ligands.
    Zhu J, Luo LY, Li JG, Chen C, Liu-Chen LY.
    J Pharmacol Exp Ther; 1997 Aug 14; 282(2):676-84. PubMed ID: 9262330
    [Abstract] [Full Text] [Related]

  • 7. Molecular basis of differences in (-)(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidiny)-cyclohexyl]benzeneacetamide-induced desensitization and phosphorylation between human and rat kappa-opioid receptors expressed in Chinese hamster ovary cells.
    Li J, Li JG, Chen C, Zhang F, Liu-Chen LY.
    Mol Pharmacol; 2002 Jan 14; 61(1):73-84. PubMed ID: 11752208
    [Abstract] [Full Text] [Related]

  • 8. (-)U50,488H [(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide] induces internalization and down-regulation of the human, but not the rat, kappa-opioid receptor: structural basis for the differential regulation.
    Zhang F, Li J, Li JG, Liu-Chen LY.
    J Pharmacol Exp Ther; 2002 Sep 14; 302(3):1184-92. PubMed ID: 12183679
    [Abstract] [Full Text] [Related]

  • 9. kappa-Opioid agonist, U50,488H, stimulates ovine fetal pituitary-adrenal function via hypothalamic arginine-vasopressin and corticotrophin-releasing factor.
    Taylor CC, Wu D, Soong Y, Yee JS, Szeto HH.
    J Pharmacol Exp Ther; 1996 May 14; 277(2):877-84. PubMed ID: 8627570
    [Abstract] [Full Text] [Related]

  • 10. U50,488H-induced internalization of the human kappa opioid receptor involves a beta-arrestin- and dynamin-dependent mechanism. Kappa receptor internalization is not required for mitogen-activated protein kinase activation.
    Li JG, Luo LY, Krupnick JG, Benovic JL, Liu-Chen LY.
    J Biol Chem; 1999 Apr 23; 274(17):12087-94. PubMed ID: 10207034
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of T cell superantigen responses following treatment with the kappa-opioid agonist U50,488H.
    Guan L, Eisenstein TK, Adler MW, Rogers TJ.
    J Neuroimmunol; 1997 May 23; 75(1-2):163-8. PubMed ID: 9143250
    [Abstract] [Full Text] [Related]

  • 12. The Protective Effects of Κ-Opioid Receptor Stimulation in Hypoxic Pulmonary Hypertension Involve Inhibition of Autophagy Through the AMPK-MTOR Pathway.
    Zhou Y, Wang Y, Wang X, Tian X, Zhang S, Yang F, Guo H, Fan R, Feng N, Jia M, Gu X, Wang Y, Li J, Pei J.
    Cell Physiol Biochem; 2017 May 23; 44(5):1965-1979. PubMed ID: 29224002
    [Abstract] [Full Text] [Related]

  • 13. Differential regulation of the human kappa opioid receptor by agonists: etorphine and levorphanol reduced dynorphin A- and U50,488H-induced internalization and phosphorylation.
    Li JG, Zhang F, Jin XL, Liu-Chen LY.
    J Pharmacol Exp Ther; 2003 May 23; 305(2):531-40. PubMed ID: 12606694
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of interleukin-1 and tumor necrosis factor-alpha synthesis following treatment of macrophages with the kappa opioid agonist U50, 488H.
    Belkowski SM, Alicea C, Eisenstein TK, Adler MW, Rogers TJ.
    J Pharmacol Exp Ther; 1995 Jun 23; 273(3):1491-6. PubMed ID: 7791124
    [Abstract] [Full Text] [Related]

  • 15. Cardiovascular and respiratory actions of U50,488H in the unanaesthetized ovine foetus.
    Szeto HH, Wu D, Cheng PY, Soong Y, Taylor CC, Yee J.
    Eur J Pharmacol; 1996 Feb 15; 297(1-2):77-82. PubMed ID: 8851169
    [Abstract] [Full Text] [Related]

  • 16. Stimulation of kappa-opioid receptor reduces isoprenaline-induced cardiac hypertrophy and fibrosis.
    Yin W, Zhang P, Huang JH, Zhang QY, Fan R, Li J, Zhou JJ, Hu YZ, Guo HT, Zhang SM, Wang YM, Kaye AD, Gu CH, Liu JC, Cheng L, Cui Q, Yi DH, Pei JM.
    Eur J Pharmacol; 2009 Apr 01; 607(1-3):135-42. PubMed ID: 19233160
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of primary murine macrophage cytokine production in vitro following treatment with the kappa-opioid agonist U50,488H.
    Alicea C, Belkowski S, Eisenstein TK, Adler MW, Rogers TJ.
    J Neuroimmunol; 1996 Jan 01; 64(1):83-90. PubMed ID: 8598393
    [Abstract] [Full Text] [Related]

  • 18. Kappa-opioid receptor agonist U50,488H modulates cocaine and morphine self-administration in drug-naive rats and mice.
    Kuzmin AV, Semenova S, Gerrits MA, Zvartau EE, Van Ree JM.
    Eur J Pharmacol; 1997 Mar 05; 321(3):265-71. PubMed ID: 9085036
    [Abstract] [Full Text] [Related]

  • 19. Chronic U50,488H abolishes inositol 1,4,5-trisphosphate and intracellular Ca2+ elevations evoked by kappa-opioid receptor in rat myocytes.
    Sheng JZ, Wong TM.
    Eur J Pharmacol; 1996 Jul 04; 307(3):323-9. PubMed ID: 8836621
    [Abstract] [Full Text] [Related]

  • 20. kappa -opioid receptor stimulation induces arrhythmia in the isolated rat heart via the protein kinase C/Na(+)-H(+)exchange pathway.
    Bian JS, Pei JM, Cheung CS, Zhang WM, Wong TM.
    J Mol Cell Cardiol; 2000 Aug 04; 32(8):1415-27. PubMed ID: 10900168
    [Abstract] [Full Text] [Related]

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