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323 related items for PubMed ID: 8394782

  • 1. A human cell line proficient in O6-methylguanine-DNA-methyltransferase and hypersensitive to alkylating agents.
    Lefebvre P, Laval F.
    Carcinogenesis; 1993 Aug; 14(8):1671-5. PubMed ID: 8394782
    [Abstract] [Full Text] [Related]

  • 2. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
    Dosch J, Kaina B.
    Oncogene; 1996 Nov 07; 13(9):1927-35. PubMed ID: 8934539
    [Abstract] [Full Text] [Related]

  • 3. Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
    Dolan ME, Norbeck L, Clyde C, Hora NK, Erickson LC, Pegg AE.
    Carcinogenesis; 1989 Sep 07; 10(9):1613-9. PubMed ID: 2766456
    [Abstract] [Full Text] [Related]

  • 4. Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents.
    Kaina B, Fritz G, Mitra S, Coquerelle T.
    Carcinogenesis; 1991 Oct 07; 12(10):1857-67. PubMed ID: 1657427
    [Abstract] [Full Text] [Related]

  • 5. Exogenous O6-methylguanine inhibits adduct removal and sensitizes human cells to killing by the chemical carcinogen N-methyl-N'-nitro-N-nitrosoguanidine.
    Babich MA, Day RS.
    Mutat Res; 1987 Nov 07; 184(3):245-54. PubMed ID: 3670328
    [Abstract] [Full Text] [Related]

  • 6. The role of O6-alkylguanine in cell killing and mutagenesis in Chinese hamster ovary cells.
    Dunn WC, Tano K, Horesovsky GJ, Preston RJ, Mitra S.
    Carcinogenesis; 1991 Jan 07; 12(1):83-9. PubMed ID: 1988186
    [Abstract] [Full Text] [Related]

  • 7. Isolation of clones displaying enhanced resistance to methylating agents in O6-methylguanine-DNA methyltransferase-proficient CHO cells.
    Aquilina G, Frosina G, Zijno A, Di Muccio A, Dogliotti E, Abbondandolo A, Bignami M.
    Carcinogenesis; 1988 Jul 07; 9(7):1217-22. PubMed ID: 3383340
    [Abstract] [Full Text] [Related]

  • 8. Transfectant CHO cells expressing O6-alkylguanine-DNA-alkyltransferase display increased resistance to DNA damage other than O6-guanine alkylation.
    Barrows LR, Borchers AH, Paxton MB.
    Carcinogenesis; 1987 Dec 07; 8(12):1853-9. PubMed ID: 2824084
    [Abstract] [Full Text] [Related]

  • 9. Expression of human O6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents.
    Wu ZN, Chan CL, Eastman A, Bresnick E.
    Cancer Res; 1992 Jan 01; 52(1):32-5. PubMed ID: 1727384
    [Abstract] [Full Text] [Related]

  • 10. Quantitative assessment of the role of O6-methylguanine in the initiation of carcinogenesis by methylating agents.
    Doniger J, Day RS, DiPaolo JA.
    Proc Natl Acad Sci U S A; 1985 Jan 01; 82(2):421-5. PubMed ID: 3855560
    [Abstract] [Full Text] [Related]

  • 11. The O6-methylguanine-DNA-methyltransferase activity of rat hepatoma cells is increased after a single exposure to alkylating agents.
    Frosina G, Laval F.
    Carcinogenesis; 1987 Jan 01; 8(1):91-5. PubMed ID: 3802398
    [Abstract] [Full Text] [Related]

  • 12. Adaptive resynthesis of O6-methylguanine-accepting protein can explain the differences between mammalian cells proficient and deficient in methyl excision repair.
    Waldstein EA, Cao EH, Setlow RB.
    Proc Natl Acad Sci U S A; 1982 Sep 01; 79(17):5117-21. PubMed ID: 6957853
    [Abstract] [Full Text] [Related]

  • 13. Cytotoxicity, mutations and SCEs induced by methylating agents are reduced in CHO cells expressing an active mammalian O6-methylguanine-DNA methyltransferase gene.
    Bignami M, Terlizzese M, Zijno A, Calcagnile A, Frosina G, Abbondandolo A, Dogliotti E.
    Carcinogenesis; 1987 Oct 01; 8(10):1417-21. PubMed ID: 3115613
    [Abstract] [Full Text] [Related]

  • 14. N-methyl-N'-nitro-N-nitrosoguanidine-resistant HeLa S3 cells still have little O6-methylguanine-DNA methyltransferase activity and are hypermutable by alkylating agents.
    Ishida R, Takahashi T.
    Carcinogenesis; 1987 Aug 01; 8(8):1109-13. PubMed ID: 3608093
    [Abstract] [Full Text] [Related]

  • 15. Relationship between O6-alkylguanine-DNA alkyltransferase activity and N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation, transformation, and cytotoxicity in C3H/10T1/2 cells expressing exogenous alkyltransferase genes.
    von Hofe E, Fairbairn L, Margison GP.
    Proc Natl Acad Sci U S A; 1992 Dec 01; 89(23):11199-203. PubMed ID: 1454799
    [Abstract] [Full Text] [Related]

  • 16. Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models.
    Kaina B, Ziouta A, Ochs K, Coquerelle T.
    Mutat Res; 1997 Nov 28; 381(2):227-41. PubMed ID: 9434879
    [Abstract] [Full Text] [Related]

  • 17. Kinetics of O6-methylguanine repair in human normal and ataxia telangiectasia cell lines and correlation of repair capacity with cellular sensitivity to methylating agents.
    Shiloh Y, Becker Y.
    Cancer Res; 1981 Dec 28; 41(12 Pt 1):5114-20. PubMed ID: 7307010
    [Abstract] [Full Text] [Related]

  • 18. The contribution of O6-methylguanine and methylphosphotriesters to the cytotoxicity of alkylating agents in mammalian cells.
    Hall J, Kataoka H, Stephenson C, Karran P.
    Carcinogenesis; 1988 Sep 28; 9(9):1587-93. PubMed ID: 3409462
    [Abstract] [Full Text] [Related]

  • 19. Repair of methylated bases in mammalian cells during adaptive response to alkylating agents.
    Laval F.
    Biochimie; 1985 Sep 28; 67(3-4):361-4. PubMed ID: 4041485
    [Abstract] [Full Text] [Related]

  • 20. On the quantitative relationship between O6-methylguanine residues in genomic DNA and production of sister-chromatid exchanges, mutations and lethal events in a Mer- human tumor cell line.
    Rasouli-Nia A, Sibghat-Ullah, Mirzayans R, Paterson MC, Day RS.
    Mutat Res; 1994 Mar 28; 314(2):99-113. PubMed ID: 7510369
    [Abstract] [Full Text] [Related]

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