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Journal Abstract Search


82 related items for PubMed ID: 8395246

  • 1. BAY X1005, a new selective inhibitor of leukotriene synthesis: pharmacology and pharmacokinetics.
    Müller-Peddinghaus R, Fruchtmann R, Ahr HJ, Beckermann B, Bühner K, Fugmann B, Junge B, Matzke M, Kohlsdorfer C, Raddatz S.
    J Lipid Mediat; 1993; 6(1-3):245-8. PubMed ID: 8395246
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  • 6. Mode of action of the new selective leukotriene synthesis inhibitor BAY X 1005 ((R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl acetic acid) and structurally related compounds.
    Hatzelmann A, Fruchtmann R, Mohrs KH, Raddatz S, Müller-Peddinghaus R.
    Biochem Pharmacol; 1993 Jan 07; 45(1):101-11. PubMed ID: 8381000
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  • 8. Blockade of leukotriene production by a single oral dose of MK-0591 in active ulcerative colitis.
    Hillingsø J, Kjeldsen J, Laursen LS, Lauritsen K, von Spreckelsen S, Depré M, Friedman BS, Malmström K, Shingo S, Bukhave K.
    Clin Pharmacol Ther; 1995 Mar 07; 57(3):335-41. PubMed ID: 7697951
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  • 9. Effect of a 5-lipoxygenase inhibitor on nerve growth factor-induced thermal hyperalgesia in the rat.
    Amann R, Schuligoi R, Lanz I, Peskar BA.
    Eur J Pharmacol; 1996 Jun 13; 306(1-3):89-91. PubMed ID: 8813619
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  • 10. Favorable combination effects of the leukotriene synthesis inhibitor BAY X 1005 and dexamethasone on edema formation in the arachidonic acid-induced mouse ear inflammation test.
    Burchardt ER, Müller-Peddinghaus R.
    Prostaglandins Leukot Essent Fatty Acids; 1999 Jan 13; 60(1):5-11. PubMed ID: 10319912
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  • 18. Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X1005 and other quinoline derivatives in intact cells and a cell-free system--implications for the function of 5-lipoxygenase activating protein.
    Hatzelmann A, Goossens J, Fruchtmann R, Mohrs KH, Raddatz S, Müller-Peddinghaus R.
    Biochem Pharmacol; 1994 Jun 15; 47(12):2259-68. PubMed ID: 8031320
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  • 20. Substituted (pyridylmethoxy)naphthalenes as potent and orally active 5-lipoxygenase inhibitors; synthesis, biological profile, and pharmacokinetics of L-739,010.
    Hamel P, Riendeau D, Brideau C, Chan CC, Desmarais S, Delorme D, Dubé D, Ducharme Y, Ethier D, Grimm E, Falgueyret JP, Guay J, Jones TR, Kwong E, McAuliffe M, McFarlane CS, Piechuta H, Roumi M, Tagari P, Young RN, Girard Y.
    J Med Chem; 1997 Aug 29; 40(18):2866-75. PubMed ID: 9288168
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