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144 related items for PubMed ID: 8395505

  • 1. Introduction of lysine and clot binding properties in the kringle one domain of tissue-type plasminogen activator.
    Bakker AH, van der Greef W, Rehberg EF, Marotti KR, Verheijen JH.
    J Biol Chem; 1993 Sep 05; 268(25):18496-501. PubMed ID: 8395505
    [Abstract] [Full Text] [Related]

  • 2. Domain-domain interactions in hybrids of tissue-type plasminogen activator and urokinase-type plasminogen activator.
    Bakker AH, Nieuwenbroek NM, Verheijen JH.
    Protein Eng; 1995 Dec 05; 8(12):1295-1302. PubMed ID: 8869642
    [Abstract] [Full Text] [Related]

  • 3. Involvement of aspartic and glutamic residues in kringle-2 of tissue-type plasminogen activator in lysine binding, fibrin binding and stimulation of activity as revealed by chemical modification and oligonucleotide-directed mutagenesis.
    Weening-Verhoeff EJ, Quax PH, van Leeuwen RT, Rehberg EF, Marotti KR, Verheijen JH.
    Protein Eng; 1990 Dec 05; 4(2):191-8. PubMed ID: 1963688
    [Abstract] [Full Text] [Related]

  • 4. Biochemical and functional characterization of human tissue-type plasminogen activator variants obtained by deletion and/or duplication of structural/functional domains.
    Lijnen HR, Nelles L, Van Hoef B, De Cock F, Collen D.
    J Biol Chem; 1990 Apr 05; 265(10):5677-83. PubMed ID: 2156824
    [Abstract] [Full Text] [Related]

  • 5. On the interaction of the finger and the kringle-2 domain of tissue-type plasminogen activator with fibrin. Inhibition of kringle-2 binding to fibrin by epsilon-amino caproic acid.
    van Zonneveld AJ, Veerman H, Pannekoek H.
    J Biol Chem; 1986 Oct 25; 261(30):14214-8. PubMed ID: 3021732
    [Abstract] [Full Text] [Related]

  • 6. Biochemical and functional characterization of human tissue-type plasminogen activator variants with mutagenized kringle domains.
    Collen D, Lijnen HR, Bulens F, Vandamme AM, Tulinsky A, Nelles L.
    J Biol Chem; 1990 Jul 25; 265(21):12184-91. PubMed ID: 2115513
    [Abstract] [Full Text] [Related]

  • 7. Study of tissue-type plasminogen activator binding sites on fibrin using distinct fragments of fibrinogen.
    Grailhe P, Nieuwenhuizen W, Anglés-Cano E.
    Eur J Biochem; 1994 Feb 01; 219(3):961-7. PubMed ID: 8112348
    [Abstract] [Full Text] [Related]

  • 8. Characterization of domain deletion and/or duplication mutants of a recombinant chimera of tissue-type plasminogen activator and urokinase-type plasminogen activator (rt-PA/u-PA).
    Nelles L, Lijnen HR, Van Nuffelen A, Demarsin E, Collen D.
    Thromb Haemost; 1990 Aug 13; 64(1):53-60. PubMed ID: 2148847
    [Abstract] [Full Text] [Related]

  • 9. The position of the structurally autonomous kringle 2 domain influences the functional features of tissue-type plasminogen activator.
    Bakker AH, Rehberg EF, Marotti KR, Verheijen JH.
    Protein Eng; 1995 Mar 13; 8(3):293-300. PubMed ID: 7479691
    [Abstract] [Full Text] [Related]

  • 10. Kringle glycosylation in a modified human tissue plasminogen activator improves functional properties.
    Berg DT, Burck PJ, Berg DH, Grinnell BW.
    Blood; 1993 Mar 01; 81(5):1312-22. PubMed ID: 8382971
    [Abstract] [Full Text] [Related]

  • 11. Regulation of fibrinolysis by C-terminal lysines operates through plasminogen and plasmin but not tissue-type plasminogen activator.
    Silva MM, Thelwell C, Williams SC, Longstaff C.
    J Thromb Haemost; 2012 Nov 01; 10(11):2354-60. PubMed ID: 22974122
    [Abstract] [Full Text] [Related]

  • 12. Plasmin-mediated fibrinolysis by variant recombinant tissue plasminogen activators.
    Urano S, Metzger AR, Castellino FJ.
    Proc Natl Acad Sci U S A; 1989 Apr 01; 86(8):2568-71. PubMed ID: 2523073
    [Abstract] [Full Text] [Related]

  • 13. Characterization of the interactions of plasminogen and tissue and vampire bat plasminogen activators with fibrinogen, fibrin, and the complex of D-dimer noncovalently linked to fragment E.
    Stewart RJ, Fredenburgh JC, Weitz JI.
    J Biol Chem; 1998 Jul 17; 273(29):18292-9. PubMed ID: 9660794
    [Abstract] [Full Text] [Related]

  • 14. Tissue-type plasminogen activator and its substrate Glu-plasminogen share common binding sites in limited plasmin-digested fibrin.
    de Vries C, Veerman H, Koornneef E, Pannekoek H.
    J Biol Chem; 1990 Aug 15; 265(23):13547-52. PubMed ID: 2143185
    [Abstract] [Full Text] [Related]

  • 15. Functional characterization of monoclonal antibodies directed against fibrin binding domains of tissue-type plasminogen activator.
    Wojta J, Beckmann R, Turcu L, Wagner OF, van Zonneveld AJ, Binder BR.
    J Biol Chem; 1989 May 15; 264(14):7957-61. PubMed ID: 2470738
    [Abstract] [Full Text] [Related]

  • 16. Binding of tissue-type plasminogen activator to lysine, lysine analogues, and fibrin fragments.
    de Munk GA, Caspers MP, Chang GT, Pouwels PH, Enger-Valk BE, Verheijen JH.
    Biochemistry; 1989 Sep 05; 28(18):7318-25. PubMed ID: 2510823
    [Abstract] [Full Text] [Related]

  • 17. Functional properties of the recombinant kringle-2 domain of tissue plasminogen activator produced in Escherichia coli.
    Wilhelm OG, Jaskunas SR, Vlahos CJ, Bang NU.
    J Biol Chem; 1990 Aug 25; 265(24):14606-11. PubMed ID: 2117612
    [Abstract] [Full Text] [Related]

  • 18. The role of the lysyl binding site of tissue-type plasminogen activator in the interaction with a forming fibrin clot.
    Bakker AH, Weening-Verhoeff EJ, Verheijen JH.
    J Biol Chem; 1995 May 26; 270(21):12355-60. PubMed ID: 7759476
    [Abstract] [Full Text] [Related]

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  • 20. Kinetic characterization of tissue-type plasminogen activator (t-PA) and t-PA deletion mutants.
    de Vries C, Veerman H, Nesheim ME, Pannekoek H.
    Thromb Haemost; 1991 Mar 04; 65(3):280-5. PubMed ID: 1904654
    [Abstract] [Full Text] [Related]

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