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165 related items for PubMed ID: 8395981

  • 1. Inhibition of the signalling enzyme phosphatidylinositol-3-kinase by antitumor ether lipid analogues.
    Berggren MI, Gallegos A, Dressler LA, Modest EJ, Powis G.
    Cancer Res; 1993 Sep 15; 53(18):4297-302. PubMed ID: 8395981
    [Abstract] [Full Text] [Related]

  • 2. Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues.
    Powis G, Seewald MJ, Gratas C, Melder D, Riebow J, Modest EJ.
    Cancer Res; 1992 May 15; 52(10):2835-40. PubMed ID: 1316230
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of growth factor-dependent inositol phosphate Ca2+ signaling by antitumor ether lipid analogues.
    Seewald MJ, Olsen RA, Sehgal I, Melder DC, Modest EJ, Powis G.
    Cancer Res; 1990 Aug 01; 50(15):4458-63. PubMed ID: 2369723
    [Abstract] [Full Text] [Related]

  • 4. Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (Edelfosine): molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-X(L).
    Mollinedo F, Fernández-Luna JL, Gajate C, Martín-Martín B, Benito A, Martínez-Dalmau R, Modolell M.
    Cancer Res; 1997 Apr 01; 57(7):1320-8. PubMed ID: 9102220
    [Abstract] [Full Text] [Related]

  • 5. The antitumor ether lipid 1-Q-octadecyl-2-O-methyl-rac-glycerophosphocholine (ET-18-OCH3) inhibits the association between Ras and Raf-1.
    Samadder P, Richards C, Bittman R, Bhullar RP, Arthur G.
    Anticancer Res; 2003 Apr 01; 23(3B):2291-5. PubMed ID: 12894505
    [Abstract] [Full Text] [Related]

  • 6. ET-18-OCH3 inhibits the phosphorylation and activation of p70 S6 kinase in MCF-7 cells.
    Arthur G, Samadder P, Bittman R.
    Anticancer Res; 2005 Apr 01; 25(1A):95-100. PubMed ID: 15816524
    [Abstract] [Full Text] [Related]

  • 7. Correlation of ether lipid content of human leukemia cell lines and their susceptibility to 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine.
    Chabot MC, Wykle RL, Modest EJ, Daniel LW.
    Cancer Res; 1989 Aug 15; 49(16):4441-5. PubMed ID: 2743333
    [Abstract] [Full Text] [Related]

  • 8. Platelet-derived growth factor stimulates synthesis of PtdIns(3,4,5)P3 by activating a PtdIns(4,5)P2 3-OH kinase.
    Hawkins PT, Jackson TR, Stephens LR.
    Nature; 1992 Jul 09; 358(6382):157-9. PubMed ID: 1319558
    [Abstract] [Full Text] [Related]

  • 9. Multiparametric flow cytometry of the modulation of tumor cell membrane permeability by developmental antitumor ether lipid SRI 62-834 in EMT6 mouse mammary tumor and HL-60 human promyelocytic leukemia cells.
    Dive C, Watson JV, Workman P.
    Cancer Res; 1991 Feb 01; 51(3):799-806. PubMed ID: 1988120
    [Abstract] [Full Text] [Related]

  • 10. Decreased sensitivity to 1-O-octadecyl-2-O-methyl-glycerophosphocholine in MCF-7 cells adapted for serum-free growth correlates with constitutive association of Raf-1 with cellular membranes.
    Samadder P, Arthur G.
    Cancer Res; 1999 Oct 01; 59(19):4808-15. PubMed ID: 10519389
    [Abstract] [Full Text] [Related]

  • 11. Cell kill and cytostasis by ET-18-OCH3 and heat.
    Fujiwara K, Modest EJ, Wallen CA.
    Anticancer Res; 1995 Oct 01; 15(4):1333-8. PubMed ID: 7654017
    [Abstract] [Full Text] [Related]

  • 12. Advances with phospholipid signalling as a target for anticancer drug development.
    Powis G, Berggren M, Gallegos A, Frew T, Hill S, Kozikowski A, Bonjouklian R, Zalkow L, Abraham R, Ashendel C.
    Acta Biochim Pol; 1995 Oct 01; 42(4):395-403. PubMed ID: 8852330
    [Abstract] [Full Text] [Related]

  • 13. Characterization of phosphatidylinositol and phosphatidylinositol-4-phosphate kinases in human neutrophils.
    Pike MC, Arndt C.
    J Immunol; 1988 Mar 15; 140(6):1967-73. PubMed ID: 2831274
    [Abstract] [Full Text] [Related]

  • 14. 1-O-octadecyl-2-O-methyl-glycerophosphocholine inhibits the transduction of growth signals via the MAPK cascade in cultured MCF-7 cells.
    Zhou X, Lu X, Richard C, Xiong W, Litchfield DW, Bittman R, Arthur G.
    J Clin Invest; 1996 Aug 15; 98(4):937-44. PubMed ID: 8770865
    [Abstract] [Full Text] [Related]

  • 15. The effect of ether lipid 1-O-octadecyl-2-O-methoxy-rac-glycero-3-phosphocholine and its analogues platelet activating factor and carbamyl-platelet activating factor on the biosynthesis of interleukin-6 in human thymic epithelial cells cultivated in vitro.
    Cardile V, Mascarucci P, De Simoni MG, Jiang X, Bindoni M.
    Cytokine; 1996 Sep 15; 8(9):698-701. PubMed ID: 8932980
    [Abstract] [Full Text] [Related]

  • 16. Glycosylated antitumor ether lipids are more effective against oncogene-transformed fibroblasts than alkyllysophospholipids.
    Samadder P, Byun HS, Bittman R, Arthur G.
    Anticancer Res; 1998 Sep 15; 18(1A):465-70. PubMed ID: 9568121
    [Abstract] [Full Text] [Related]

  • 17. Enhanced therapeutic effects of liposome-associated 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine.
    Ahmad I, Filep JJ, Franklin JC, Janoff AS, Masters GR, Pattassery J, Peters A, Schupsky JJ, Zha Y, Mayhew E.
    Cancer Res; 1997 May 15; 57(10):1915-21. PubMed ID: 9157985
    [Abstract] [Full Text] [Related]

  • 18. Effects of ether lipid 1-O-octadecyl-2-methoxy-rac-glycero- 3-phosphocholine and its analogs PAF and CPAF on the release of nitric oxide in primary cultures of rat astrocytes.
    Cardile V, Jiang X, Renis M, Bindoni M.
    Brain Res; 1996 Apr 09; 715(1-2):98-103. PubMed ID: 8739627
    [Abstract] [Full Text] [Related]

  • 19. The antitumor ether lipid edelfosine (ET-18-O-CH3) induces apoptosis in H-ras transformed human breast epithelial cells: by blocking ERK1/2 and p38 mitogen-activated protein kinases as potential targets.
    Na HK, Surh YJ.
    Asia Pac J Clin Nutr; 2008 Apr 09; 17 Suppl 1():204-7. PubMed ID: 18296338
    [Abstract] [Full Text] [Related]

  • 20. Dissociation of the effects of the antitumour ether lipid ET-18-OCH3 on cytosolic calcium and on apoptosis.
    Alonso MT, Gajate C, Mollinedo F, Modolell M, Alvarez J, García-Sancho J.
    Br J Pharmacol; 1997 Aug 09; 121(7):1364-8. PubMed ID: 9257915
    [Abstract] [Full Text] [Related]

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