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Journal Abstract Search

293 related items for PubMed ID: 8421499

  • 21. Catalytic strategies of self-cleaving ribozymes.
    Cochrane JC, Strobel SA.
    Acc Chem Res; 2008 Aug; 41(8):1027-35. PubMed ID: 18652494
    [Abstract] [Full Text] [Related]

  • 22. Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis.
    Jabri E, Aigner S, Cech TR.
    Biochemistry; 1997 Dec 23; 36(51):16345-54. PubMed ID: 9405070
    [Abstract] [Full Text] [Related]

  • 23. Protonated 2'-aminoguanosine as a probe of the electrostatic environment of the active site of the Tetrahymena group I ribozyme.
    Shan SO, Narlikar GJ, Herschlag D.
    Biochemistry; 1999 Aug 24; 38(34):10976-88. PubMed ID: 10460152
    [Abstract] [Full Text] [Related]

  • 24. Role of an active site guanine in hairpin ribozyme catalysis probed by exogenous nucleobase rescue.
    Kuzmin YI, Da Costa CP, Fedor MJ.
    J Mol Biol; 2004 Jul 02; 340(2):233-51. PubMed ID: 15201049
    [Abstract] [Full Text] [Related]

  • 25. Promiscuous catalysis by the tetrahymena group I ribozyme.
    Forconi M, Herschlag D.
    J Am Chem Soc; 2005 May 04; 127(17):6160-1. PubMed ID: 15853307
    [Abstract] [Full Text] [Related]

  • 26. Substitution of the 2'-hydroxyl group at position 2.1 by an amino group interferes with Mg(2+) binding and efficient cleavage by hammerhead ribozyme.
    Sioud M, Leirdal M.
    Biochem Biophys Res Commun; 1999 Aug 27; 262(2):461-6. PubMed ID: 10462497
    [Abstract] [Full Text] [Related]

  • 27. Exocyclic amine of the conserved G.U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization.
    Strobel SA, Cech TR.
    Biochemistry; 1996 Jan 30; 35(4):1201-11. PubMed ID: 8573575
    [Abstract] [Full Text] [Related]

  • 28. Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction.
    Shan S, Kravchuk AV, Piccirilli JA, Herschlag D.
    Biochemistry; 2001 May 01; 40(17):5161-71. PubMed ID: 11318638
    [Abstract] [Full Text] [Related]

  • 29. Structure and function of the hairpin ribozyme.
    Fedor MJ.
    J Mol Biol; 2000 Mar 24; 297(2):269-91. PubMed ID: 10715200
    [Abstract] [Full Text] [Related]

  • 30. Metal ion binding sites in a group II intron core.
    Sigel RK, Vaidya A, Pyle AM.
    Nat Struct Biol; 2000 Dec 24; 7(12):1111-6. PubMed ID: 11101891
    [Abstract] [Full Text] [Related]

  • 31. Probing general acid catalysis in the hammerhead ribozyme.
    Thomas JM, Perrin DM.
    J Am Chem Soc; 2009 Jan 28; 131(3):1135-43. PubMed ID: 19154176
    [Abstract] [Full Text] [Related]

  • 32. The role of the cleavage site 2'-hydroxyl in the Tetrahymena group I ribozyme reaction.
    Yoshida A, Shan So, Herschlag D, Piccirilli JA.
    Chem Biol; 2000 Feb 28; 7(2):85-96. PubMed ID: 10662698
    [Abstract] [Full Text] [Related]

  • 33. Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
    Brautigam CA, Sun S, Piccirilli JA, Steitz TA.
    Biochemistry; 1999 Jan 12; 38(2):696-704. PubMed ID: 9888810
    [Abstract] [Full Text] [Related]

  • 34. Divalent metal ions promote the formation of the 5'-splice site recognition complex in a self-splicing group II intron.
    Kruschel D, Sigel RK.
    J Inorg Biochem; 2008 Dec 12; 102(12):2147-54. PubMed ID: 18842303
    [Abstract] [Full Text] [Related]

  • 35. The cleavage step of ribonuclease P catalysis is determined by ribozyme-substrate interactions both distal and proximal to the cleavage site.
    Loria A, Pan T.
    Biochemistry; 1999 Jul 06; 38(27):8612-20. PubMed ID: 10393536
    [Abstract] [Full Text] [Related]

  • 36. The role of phosphate groups in the VS ribozyme-substrate interaction.
    Kovacheva YS, Tzokov SB, Murray IA, Grasby JA.
    Nucleic Acids Res; 2004 Jul 06; 32(21):6240-50. PubMed ID: 15576350
    [Abstract] [Full Text] [Related]

  • 37. Characterization of P8 and J8/7 elements in the conserved core of the tetrahymena group I intron ribozyme.
    Ikawa Y, Shiraishi H, Inoue T.
    Biochem Biophys Res Commun; 2000 Jan 07; 267(1):85-90. PubMed ID: 10623579
    [Abstract] [Full Text] [Related]

  • 38. A Pneumocystis carinii group I intron ribozyme that does not require 2' OH groups on its 5' exon mimic for binding to the catalytic core.
    Testa SM, Haidaris CG, Gigliotti F, Turner DH.
    Biochemistry; 1997 Dec 09; 36(49):15303-14. PubMed ID: 9398259
    [Abstract] [Full Text] [Related]

  • 39. The tetrahymena ribozyme cleaves a 5'-methylene phosphonate monoester approximately 10(2)-fold faster than a normal phosphate diester: implications for enzyme catalysis of phosphoryl transfer reactions.
    Liao X, Anjaneyulu PS, Curley JF, Hsu M, Boehringer M, Caruthers MH, Piccirilli JA.
    Biochemistry; 2001 Sep 18; 40(37):10911-26. PubMed ID: 11551186
    [Abstract] [Full Text] [Related]

  • 40. Identification of an active site ligand for a group I ribozyme catalytic metal ion.
    Szewczak AA, Kosek AB, Piccirilli JA, Strobel SA.
    Biochemistry; 2002 Feb 26; 41(8):2516-25. PubMed ID: 11851398
    [Abstract] [Full Text] [Related]

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