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Journal Abstract Search


221 related items for PubMed ID: 8421689

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  • 3. B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice.
    Brinkmann U, Pai LH, FitzGerald DJ, Willingham M, Pastan I.
    Proc Natl Acad Sci U S A; 1991 Oct 01; 88(19):8616-20. PubMed ID: 1924323
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  • 4. Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv.
    Reiter Y, Brinkmann U, Webber KO, Jung SH, Lee B, Pastan I.
    Protein Eng; 1994 May 01; 7(5):697-704. PubMed ID: 8073039
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  • 7. Stabilization of the Fv fragments in recombinant immunotoxins by disulfide bonds engineered into conserved framework regions.
    Reiter Y, Brinkmann U, Kreitman RJ, Jung SH, Lee B, Pastan I.
    Biochemistry; 1994 May 10; 33(18):5451-9. PubMed ID: 7910034
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  • 8. Recombinant single-chain and disulfide-stabilized Fv-immunotoxins that cause complete regression of a human colon cancer xenograft in nude mice.
    Reiter Y, Wright AF, Tonge DW, Pastan I.
    Int J Cancer; 1996 Jul 03; 67(1):113-23. PubMed ID: 8690511
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  • 9. A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
    Brinkmann U, Reiter Y, Jung SH, Lee B, Pastan I.
    Proc Natl Acad Sci U S A; 1993 Aug 15; 90(16):7538-42. PubMed ID: 8356052
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  • 12. Cytotoxic and antitumor activity of a recombinant immunotoxin composed of disulfide-stabilized anti-Tac Fv fragment and truncated Pseudomonas exotoxin.
    Reiter Y, Kreitman RJ, Brinkmann U, Pastan I.
    Int J Cancer; 1994 Jul 01; 58(1):142-9. PubMed ID: 8014011
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  • 13. Construction and in vitro evaluation of RFT5(scFv)-ETA', a new recombinant single-chain immunotoxin with specific cytotoxicity toward CD25+ Hodgkin-derived cell lines.
    Barth S, Huhn M, Wels W, Diehl V, Engert A.
    Int J Mol Med; 1998 Jan 01; 1(1):249-56. PubMed ID: 9852227
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  • 14. Cloning, expression and characterization of the Fv fragments of the anti-carbohydrate mAbs B1 and B5 as single-chain immunotoxins.
    Benhar I, Pastan I.
    Protein Eng; 1994 Dec 01; 7(12):1509-15. PubMed ID: 7716163
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  • 17. The recombinant immunotoxin anti-Tac(Fv)-Pseudomonas exotoxin 40 is cytotoxic toward peripheral blood malignant cells from patients with adult T-cell leukemia.
    Kreitman RJ, Chaudhary VK, Waldmann T, Willingham MC, FitzGerald DJ, Pastan I.
    Proc Natl Acad Sci U S A; 1990 Nov 01; 87(21):8291-5. PubMed ID: 2236041
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  • 18. Single-chain immunotoxin fusions between anti-Tac and Pseudomonas exotoxin: relative importance of the two toxin disulfide bonds.
    Kreitman RJ, Batra JK, Seetharam S, Chaudhary VK, FitzGerald DJ, Pastan I.
    Bioconjug Chem; 1993 Nov 01; 4(2):112-20. PubMed ID: 7873642
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  • 20. Improved binding and antitumor activity of a recombinant anti-erbB2 immunotoxin by disulfide stabilization of the Fv fragment.
    Reiter Y, Brinkmann U, Jung SH, Lee B, Kasprzyk PG, King CR, Pastan I.
    J Biol Chem; 1994 Jul 15; 269(28):18327-31. PubMed ID: 7913461
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