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Journal Abstract Search

180 related items for PubMed ID: 8421693

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  • 2. Nonlocal structural perturbations in a mutant human insulin: sequential resonance assignment and 13C-isotope-aided 2D-NMR studies of [PheB24-->Gly]insulin with implications for receptor recognition.
    Hua QX, Shoelson SE, Weiss MA.
    Biochemistry; 1992 Dec 01; 31(47):11940-51. PubMed ID: 1445924
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  • 3. Mutations at the dimer, hexamer, and receptor-binding surfaces of insulin independently affect insulin-insulin and insulin-receptor interactions.
    Shoelson SE, Lu ZX, Parlautan L, Lynch CS, Weiss MA.
    Biochemistry; 1992 Feb 18; 31(6):1757-67. PubMed ID: 1737029
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  • 6. A structural switch in a mutant insulin exposes key residues for receptor binding.
    Ludvigsen S, Olsen HB, Kaarsholm NC.
    J Mol Biol; 1998 May 29; 279(1):1-7. PubMed ID: 9636695
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  • 7. Receptor binding redefined by a structural switch in a mutant human insulin.
    Hua QX, Shoelson SE, Kochoyan M, Weiss MA.
    Nature; 1991 Nov 21; 354(6350):238-41. PubMed ID: 1961250
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  • 10. Role of the phenylalanine B24 side chain in directing insulin interaction with its receptor. Importance of main chain conformation.
    Mirmira RG, Tager HS.
    J Biol Chem; 1989 Apr 15; 264(11):6349-54. PubMed ID: 2649499
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  • 12. Solution structure of the superactive monomeric des-[Phe(B25)] human insulin mutant: elucidation of the structural basis for the monomerization of des-[Phe(B25)] insulin and the dimerization of native insulin.
    Jørgensen AM, Olsen HB, Balschmidt P, Led JJ.
    J Mol Biol; 1996 Apr 05; 257(3):684-99. PubMed ID: 8648633
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  • 13. Flexibility and bioactivity of insulin: an NMR investigation of the solution structure and folding of an unusually flexible human insulin mutant with increased biological activity.
    Keller D, Clausen R, Josefsen K, Led JJ.
    Biochemistry; 2001 Sep 04; 40(35):10732-40. PubMed ID: 11524020
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  • 18. Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
    Weiss MA, Wan Z, Zhao M, Chu YC, Nakagawa SH, Burke GT, Jia W, Hellmich R, Katsoyannis PG.
    J Mol Biol; 2002 Jan 11; 315(2):103-11. PubMed ID: 11779231
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