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Journal Abstract Search

202 related items for PubMed ID: 8422359

  • 1. Effect of the Z mutation on the physical and inhibitory properties of alpha 1-antitrypsin.
    Lomas DA, Evans DL, Stone SR, Chang WS, Carrell RW.
    Biochemistry; 1993 Jan 19; 32(2):500-8. PubMed ID: 8422359
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  • 2. alpha 1-Antitrypsin Mmalton (Phe52-deleted) forms loop-sheet polymers in vivo. Evidence for the C sheet mechanism of polymerization.
    Lomas DA, Elliott PR, Sidhar SK, Foreman RC, Finch JT, Cox DW, Whisstock JC, Carrell RW.
    J Biol Chem; 1995 Jul 14; 270(28):16864-70. PubMed ID: 7622502
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  • 5. The mechanism of Z alpha 1-antitrypsin accumulation in the liver.
    Lomas DA, Evans DL, Finch JT, Carrell RW.
    Nature; 1992 Jun 18; 357(6379):605-7. PubMed ID: 1608473
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  • 6. A protein structural approach to the solution of biological problems: alpha 1-antitrypsin as a recent example.
    Lomas DA, Carrell RW.
    Am J Physiol; 1993 Sep 18; 265(3 Pt 1):L211-9. PubMed ID: 8214081
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  • 7. Preparation and characterization of latent alpha 1-antitrypsin.
    Lomas DA, Elliott PR, Chang WS, Wardell MR, Carrell RW.
    J Biol Chem; 1995 Mar 10; 270(10):5282-8. PubMed ID: 7890640
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  • 8. The Z type variation of human alpha 1-antitrypsin causes a protein folding defect.
    Yu MH, Lee KN, Kim J.
    Nat Struct Biol; 1995 May 10; 2(5):363-7. PubMed ID: 7664092
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  • 11. Probing the local conformational change of alpha1-antitrypsin.
    Baek JH, Im H, Kang UB, Seong KM, Lee C, Kim J, Yu MH.
    Protein Sci; 2007 Sep 10; 16(9):1842-50. PubMed ID: 17660256
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  • 13. A thermostable mutation located at the hydrophobic core of alpha 1-antitrypsin suppresses the folding defect of the Z-type variant.
    Kim J, Lee KN, Yi GS, Yu MH.
    J Biol Chem; 1995 Apr 14; 270(15):8597-601. PubMed ID: 7721761
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  • 14. 6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z alpha(1)-antitrypsin-related cirrhosis.
    Mahadeva R, Dafforn TR, Carrell RW, Lomas DA.
    J Biol Chem; 2002 Mar 01; 277(9):6771-4. PubMed ID: 11773044
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  • 15. The effect of the Z mutation on the ability of alpha 1-antitrypsin to prevent neutrophil mediated tissue damage.
    Llewellyn-Jones CG, Lomas DA, Carrell RW, Stockley RA.
    Biochim Biophys Acta; 1994 Nov 29; 1227(3):155-60. PubMed ID: 7986822
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  • 17. A single-chain variable fragment intrabody prevents intracellular polymerization of Z α1-antitrypsin while allowing its antiproteinase activity.
    Ordóñez A, Pérez J, Tan L, Dickens JA, Motamedi-Shad N, Irving JA, Haq I, Ekeowa U, Marciniak SJ, Miranda E, Lomas DA.
    FASEB J; 2015 Jun 29; 29(6):2667-78. PubMed ID: 25757566
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  • 18. Effects of mutations in the hinge region of serpins.
    Hopkins PC, Carrell RW, Stone SR.
    Biochemistry; 1993 Aug 03; 32(30):7650-7. PubMed ID: 8347575
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  • 19. Structural change in β-sheet A of Z α(1)-antitrypsin is responsible for accelerated polymerization and disease.
    Knaupp AS, Bottomley SP.
    J Mol Biol; 2011 Nov 04; 413(4):888-98. PubMed ID: 21945526
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