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Journal Abstract Search


141 related items for PubMed ID: 8427512

  • 1. Inhibition of interleukin 1 beta induced rat and human cartilage degradation in vitro by the metalloproteinase inhibitor U27391.
    Seed MP, Ismaiel S, Cheung CY, Thomson TA, Gardner CR, Atkins RM, Elson CJ.
    Ann Rheum Dis; 1993 Jan; 52(1):37-43. PubMed ID: 8427512
    [Abstract] [Full Text] [Related]

  • 2. Investigation of the role of metalloproteinases in recombinant human interleukin-1 beta-induced degradation of rat femoral head cartilage.
    Seed MP, Thomson TA, Gardner CR.
    Drugs Exp Clin Res; 1991 Jan; 17(7):355-61. PubMed ID: 1794302
    [Abstract] [Full Text] [Related]

  • 3. Studies on interleukin-1 beta induced glycosaminoglycan release from rat femoral head cartilage in-vitro.
    Clay K, Seed MP, Clements-Jewery S.
    J Pharm Pharmacol; 1989 Jul; 41(7):503-4. PubMed ID: 2570864
    [No Abstract] [Full Text] [Related]

  • 4. Recombinant human interleukin-1 alpha and recombinant human interleukin-1 beta stimulate cartilage matrix degradation and inhibit glycosaminoglycan synthesis.
    Smith RJ, Rohloff NA, Sam LM, Justen JM, Deibel MR, Cornette JC.
    Inflammation; 1989 Aug; 13(4):367-82. PubMed ID: 2668162
    [Abstract] [Full Text] [Related]

  • 5. Pharmacological influence of antirheumatic drugs on proteoglycans from interleukin-1 treated articular cartilage.
    Steinmeyer J, Daufeldt S.
    Biochem Pharmacol; 1997 Jun 01; 53(11):1627-35. PubMed ID: 9264315
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of articular cartilage degradation in culture by a novel nonpeptidic matrix metalloproteinase inhibitor.
    Billinghurst RC, O'Brien K, Poole AR, McIlwraith CW.
    Ann N Y Acad Sci; 1999 Jun 30; 878():594-7. PubMed ID: 10415783
    [No Abstract] [Full Text] [Related]

  • 7. Effects of the hydroxamic acid derivate Ro 31-4724 on the metabolism and morphology of interleukin-1-treated cartilage explants.
    Steinmeyer J, Daufeldt S, Kalbhen DA.
    Pharmacology; 1997 Aug 30; 55(2):95-108. PubMed ID: 9323309
    [Abstract] [Full Text] [Related]

  • 8. The proteoglycan metabolism, morphology and viability of articular cartilage treated with a synthetic matrix metalloproteinase inhibitor.
    Steinmeyer J, Daufeldt S, Kalbhen DA.
    Res Exp Med (Berl); 1997 Aug 30; 197(2):63-79. PubMed ID: 9380952
    [Abstract] [Full Text] [Related]

  • 9. Transforming growth factor-beta causes partial inhibition of interleukin 1-stimulated cartilage degradation in vitro.
    Andrews HJ, Edwards TA, Cawston TE, Hazleman BL.
    Biochem Biophys Res Commun; 1989 Jul 14; 162(1):144-50. PubMed ID: 2787634
    [Abstract] [Full Text] [Related]

  • 10. In vivo model of cartilage degradation--effects of a matrix metalloproteinase inhibitor.
    Karran EH, Young TJ, Markwell RE, Harper GP.
    Ann Rheum Dis; 1995 Aug 14; 54(8):662-9. PubMed ID: 7677443
    [Abstract] [Full Text] [Related]

  • 11. Matrix metalloproteinase inhibitor CGS 27023A protects COMP and proteoglycan in the bovine articular cartilage but not the release of their fragments from cartilage after prolonged stimulation in vitro with IL-1 alpha.
    Ganu V, Melton R, Wang W, Roberts D.
    Ann N Y Acad Sci; 1999 Jun 30; 878():607-11. PubMed ID: 10415786
    [No Abstract] [Full Text] [Related]

  • 12. IL-1 beta induces the degradation of equine articular cartilage by a mechanism that is not mediated by nitric oxide.
    Bird JL, Wells T, Platt D, Bayliss MT.
    Biochem Biophys Res Commun; 1997 Sep 08; 238(1):81-5. PubMed ID: 9299456
    [Abstract] [Full Text] [Related]

  • 13. Induction of articular cartilage degradation by recombinant interleukin 1 alpha and 1 beta.
    Smith RL, Allison AC, Schurman DJ.
    Connect Tissue Res; 1989 Sep 08; 18(4):307-16. PubMed ID: 2787228
    [Abstract] [Full Text] [Related]

  • 14. The effect of naproxen and interleukin-1 on proteoglycan catabolism and on neutral metalloproteinase activity in normal articular cartilage in vitro.
    Glazer PA, Rosenwasser MP, Ratcliffe A.
    J Clin Pharmacol; 1993 Feb 08; 33(2):109-14. PubMed ID: 8440758
    [Abstract] [Full Text] [Related]

  • 15. Effects of stromelysin activity on proteoglycan degradation of canine articular cartilage explants.
    Todhunter RJ, Yeh LA, Sheldon A, Grisanzio L, Walker SL, Burton-Wurster N, Lust G.
    Am J Vet Res; 1995 Sep 08; 56(9):1241-7. PubMed ID: 7486406
    [Abstract] [Full Text] [Related]

  • 16. Differential responses of human articular cartilage to retinol.
    Jubb RW.
    Ann Rheum Dis; 1984 Dec 08; 43(6):833-40. PubMed ID: 6524986
    [Abstract] [Full Text] [Related]

  • 17. Modulation by transforming growth factor-beta 1 and interleukin-1 beta of proteoglycan release and chondrodisaccharide composition in porcine articular cartilage.
    Zanni M, Tamburro A, Santone I, Rotilio D.
    Semin Thromb Hemost; 1994 Dec 08; 20(2):159-67. PubMed ID: 7997887
    [Abstract] [Full Text] [Related]

  • 18. Regulation of matrix metabolism in equine cartilage explant cultures by interleukin 1.
    MacDonald MH, Stover SM, Willits NH, Benton HP.
    Am J Vet Res; 1992 Dec 08; 53(12):2278-85. PubMed ID: 1476308
    [Abstract] [Full Text] [Related]

  • 19. Comparison of the degradation of type II collagen and proteoglycan in nasal and articular cartilages induced by interleukin-1 and the selective inhibition of type II collagen cleavage by collagenase.
    Billinghurst RC, Wu W, Ionescu M, Reiner A, Dahlberg L, Chen J, van Wart H, Poole AR.
    Arthritis Rheum; 2000 Mar 08; 43(3):664-72. PubMed ID: 10728761
    [Abstract] [Full Text] [Related]

  • 20. Effect of interleukin 1 on articular cartilage from young and aged horses and comparison with metabolism of osteoarthritic cartilage.
    Morris EA, Treadwell BV.
    Am J Vet Res; 1994 Jan 08; 55(1):138-46. PubMed ID: 8141486
    [Abstract] [Full Text] [Related]


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