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218 related items for PubMed ID: 8428728

  • 1. Clearance by the liver in cirrhosis. I. Relationship between propranolol metabolism in vitro and its extraction by the perfused liver in the rat.
    Fenyves D, Gariépy L, Villeneuve JP.
    Hepatology; 1993 Feb; 17(2):301-6. PubMed ID: 8428728
    [Abstract] [Full Text] [Related]

  • 2. Hepatic artery flow and propranolol metabolism in perfused cirrhotic rat liver.
    Le Couteur DG, Hickey H, Harvey PJ, Gready J, McLean AJ.
    J Pharmacol Exp Ther; 1999 Jun; 289(3):1553-8. PubMed ID: 10336552
    [Abstract] [Full Text] [Related]

  • 3. Intact hepatocyte theory of impaired drug metabolism in experimental cirrhosis in the rat.
    Wood AJ, Villeneuve JP, Branch RA, Rogers LW, Shand DG.
    Gastroenterology; 1979 Jun; 76(6):1358-62. PubMed ID: 437433
    [Abstract] [Full Text] [Related]

  • 4. Impaired elimination of propranolol due to right heart failure: drug clearance in the isolated liver and its relationship to intrinsic metabolic capacity.
    Ng CY, Ghabrial H, Morgan DJ, Ching MS, Smallwood RA, Angus PW.
    Drug Metab Dispos; 2000 Oct; 28(10):1217-21. PubMed ID: 10997943
    [Abstract] [Full Text] [Related]

  • 5. Hepatic enzyme activity is the major factor determining elimination rate of high-clearance drugs in cirrhosis.
    Callaghan R, Desmond PV, Paull P, Mashford ML.
    Hepatology; 1993 Jul; 18(1):54-60. PubMed ID: 8325621
    [Abstract] [Full Text] [Related]

  • 6. Reduced extraction of I-propranolol by perfused rat liver in the presence of uremic blood.
    Terao N, Shen DD.
    J Pharmacol Exp Ther; 1985 May; 233(2):277-84. PubMed ID: 3999018
    [Abstract] [Full Text] [Related]

  • 7. Clearance by the liver in cirrhosis. II. Characterization of propranolol uptake with the multiple-indicator dilution technique.
    Gariépy L, Fenyves D, Kassissia I, Villeneuve JP.
    Hepatology; 1993 Oct; 18(4):823-31. PubMed ID: 8406355
    [Abstract] [Full Text] [Related]

  • 8. Reduced hepatic clearance of propranolol induced by chronic carbon tetrachloride treatment in rats.
    Iwamoto K, Watanabe J, Araki K, Satoh M, Deguchi N.
    J Pharmacol Exp Ther; 1985 Aug; 234(2):470-5. PubMed ID: 4020680
    [Abstract] [Full Text] [Related]

  • 9. Carbon tetrachloride-induced cirrhosis in rats: influence of the acute effects of the toxin on glucose metabolism.
    Mion F, Géloën A, Agosto E, Minaire Y.
    Hepatology; 1996 Mar; 23(3):582-8. PubMed ID: 8617440
    [Abstract] [Full Text] [Related]

  • 10. Clearance by the liver in cirrhosis. III. Propranolol uptake by the isolated perfused human liver.
    Villeneuve JP, Dagenais M, Huet PM, Lapointe R, Roy A, Marleau D.
    Can J Physiol Pharmacol; 1996 Dec; 74(12):1327-32. PubMed ID: 9047043
    [Abstract] [Full Text] [Related]

  • 11. Reduction in hepatic endothelin-1 clearance in cirrhosis.
    Tran Duc AT, Schwab AJ, Simard A, Villeneuve L, Dupuis J.
    Clin Sci (Lond); 2003 Aug; 105(2):227-34. PubMed ID: 12708965
    [Abstract] [Full Text] [Related]

  • 12. Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance.
    Rane A, Wilkinson GR, Shand DG.
    J Pharmacol Exp Ther; 1977 Feb; 200(2):420-4. PubMed ID: 839445
    [Abstract] [Full Text] [Related]

  • 13. Determination of in vivo hepatic extraction ratio from in vitro metabolism by rat hepatocytes.
    Singh K, Tripp SL, Dunton AW, Douglas FL, Rakhit A.
    Drug Metab Dispos; 1991 Feb; 19(5):990-6. PubMed ID: 1686248
    [Abstract] [Full Text] [Related]

  • 14. Increased sensitivity of propranolol clearance to reduced oxygen delivery in the isolated perfused cirrhotic rat liver.
    Hickey PL, McLean AJ, Angus PW, Choo EF, Morgan DJ.
    Gastroenterology; 1996 Oct; 111(4):1039-48. PubMed ID: 8831600
    [Abstract] [Full Text] [Related]

  • 15. Alteration of the pharmacokinetics and metabolism of propranolol and antipyrine elicited by indwelling catheters in the rat.
    Chindavijak B, Belpaire FM, De Smet F, Bogaert MG.
    J Pharmacol Exp Ther; 1988 Sep; 246(3):1075-9. PubMed ID: 3418510
    [Abstract] [Full Text] [Related]

  • 16. Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation.
    Hung DY, Siebert GA, Chang P, Whitehouse MW, Fletcher L, Crawford DH, Roberts MS.
    Am J Physiol Gastrointest Liver Physiol; 2006 Feb; 290(2):G343-51. PubMed ID: 16166348
    [Abstract] [Full Text] [Related]

  • 17. Disposition kinetics of propranolol isomers in the perfused rat liver.
    Hung DY, Siebert GA, Chang P, Anissimov YG, Roberts MS.
    J Pharmacol Exp Ther; 2004 Nov; 311(2):822-9. PubMed ID: 15192084
    [Abstract] [Full Text] [Related]

  • 18. Ion-trapping, microsomal binding, and unbound drug distribution in the hepatic retention of basic drugs.
    Siebert GA, Hung DY, Chang P, Roberts MS.
    J Pharmacol Exp Ther; 2004 Jan; 308(1):228-35. PubMed ID: 14566005
    [Abstract] [Full Text] [Related]

  • 19. [Relationship of propranolol pharmacokinetic parameters with portosystemic shunt in CCl4-induced cirrhotic rats].
    Koh DH, Park GT, Kim JM, Yun YS, Lee SH, Kim DU, Kim JB, Choi YY, Kang JS, Choi HS, Hahm JS, Lee MH.
    Taehan Kan Hakhoe Chi; 2002 Sep; 8(3):277-87. PubMed ID: 12499785
    [Abstract] [Full Text] [Related]

  • 20. Effect of inflammation and proadifen on the disposition of antipyrine, lignocaine and propranolol in rat isolated perfused liver.
    Chindavijak B, Belpaire FM, Bogaert MG.
    J Pharm Pharmacol; 1987 Dec; 39(12):997-1002. PubMed ID: 2894448
    [Abstract] [Full Text] [Related]

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