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130 related items for PubMed ID: 8431514
1. Affinity purification and characterization of anti-Tac(Fv)-C3-PE38KDEL: A highly potent cytotoxic agent specific to cells bearing IL-2 receptors. Spence C, Nachman M, Gately MK, Kreitman RJ, Pastan I, Bailon P. Bioconjug Chem; 1993; 4(1):63-8. PubMed ID: 8431514 [Abstract] [Full Text] [Related]
2. Stabilization of the Fv fragments in recombinant immunotoxins by disulfide bonds engineered into conserved framework regions. Reiter Y, Brinkmann U, Kreitman RJ, Jung SH, Lee B, Pastan I. Biochemistry; 1994 May 10; 33(18):5451-9. PubMed ID: 7910034 [Abstract] [Full Text] [Related]
7. Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia. Kreitman RJ, Chaudhary VK, Kozak RW, FitzGerald DJ, Waldman TA, Pastan I. Blood; 1992 Nov 01; 80(9):2344-52. PubMed ID: 1421405 [Abstract] [Full Text] [Related]
9. A method for increasing the yield of properly folded recombinant fusion proteins: single-chain immunotoxins from renaturation of bacterial inclusion bodies. Buchner J, Pastan I, Brinkmann U. Anal Biochem; 1992 Sep 01; 205(2):263-70. PubMed ID: 1332541 [Abstract] [Full Text] [Related]
11. Anti-Tac(Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells. Batra JK, FitzGerald D, Gately M, Chaudhary VK, Pastan I. J Biol Chem; 1990 Sep 05; 265(25):15198-202. PubMed ID: 2118522 [Abstract] [Full Text] [Related]
12. Cytotoxicity of recombinant Fab and Fv immunotoxins on adult T-cell leukemia lymph node and blood cells in the presence of soluble interleukin-2 receptor. Saito T, Kreitman RJ, Hanada S, Makino T, Utsunomiya A, Sumizawa T, Arima T, Chang CN, Hudson D, Pastan I. Cancer Res; 1994 Feb 15; 54(4):1059-64. PubMed ID: 8313362 [Abstract] [Full Text] [Related]
13. Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv. Reiter Y, Brinkmann U, Webber KO, Jung SH, Lee B, Pastan I. Protein Eng; 1994 May 15; 7(5):697-704. PubMed ID: 8073039 [Abstract] [Full Text] [Related]
20. B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice. Brinkmann U, Pai LH, FitzGerald DJ, Willingham M, Pastan I. Proc Natl Acad Sci U S A; 1991 Oct 01; 88(19):8616-20. PubMed ID: 1924323 [Abstract] [Full Text] [Related] Page: [Next] [New Search]