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130 related items for PubMed ID: 8431514

  • 21. Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy.
    Chen H, Gao J, Lu Y, Kou G, Zhang H, Fan L, Sun Z, Guo Y, Zhong Y.
    J Control Release; 2008 Jun 24; 128(3):209-16. PubMed ID: 18450313
    [Abstract] [Full Text] [Related]

  • 22. Recombinant immunotoxin containing a disulfide-stabilized Fv directed at erbB2 that does not require proteolytic activation.
    Kuan CT, Pastan I.
    Biochemistry; 1996 Mar 05; 35(9):2872-7. PubMed ID: 8608123
    [Abstract] [Full Text] [Related]

  • 23. Recombinant immunotoxins containing the VH or VL domain of monoclonal antibody B3 fused to Pseudomonas exotoxin.
    Brinkmann U, Lee BK, Pastan I.
    J Immunol; 1993 Apr 01; 150(7):2774-82. PubMed ID: 8454854
    [Abstract] [Full Text] [Related]

  • 24. A bivalent disulfide-stabilized Fv with improved antigen binding to erbB2.
    Bera TK, Onda M, Brinkmann U, Pastan I.
    J Mol Biol; 1998 Aug 21; 281(3):475-83. PubMed ID: 9698563
    [Abstract] [Full Text] [Related]

  • 25. Recombinant single-chain and disulfide-stabilized Fv-immunotoxins that cause complete regression of a human colon cancer xenograft in nude mice.
    Reiter Y, Wright AF, Tonge DW, Pastan I.
    Int J Cancer; 1996 Jul 03; 67(1):113-23. PubMed ID: 8690511
    [Abstract] [Full Text] [Related]

  • 26. A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxin.
    Chaudhary VK, Gallo MG, FitzGerald DJ, Pastan I.
    Proc Natl Acad Sci U S A; 1990 Dec 03; 87(23):9491-4. PubMed ID: 2251289
    [Abstract] [Full Text] [Related]

  • 27. A recombinant immunotoxin that is active on prostate cancer cells and that is composed of the Fv region of monoclonal antibody PR1 and a truncated form of Pseudomonas exotoxin.
    Brinkmann U, Gallo M, Brinkmann E, Kunwar S, Pastan I.
    Proc Natl Acad Sci U S A; 1993 Jan 15; 90(2):547-51. PubMed ID: 8421689
    [Abstract] [Full Text] [Related]

  • 28. Characterization of B1(Fv)PE38 and B1(dsFv)PE38: single-chain and disulfide-stabilized Fv immunotoxins with increased activity that cause complete remissions of established human carcinoma xenografts in nude mice.
    Benhar I, Pastan I.
    Clin Cancer Res; 1995 Sep 15; 1(9):1023-9. PubMed ID: 9816075
    [Abstract] [Full Text] [Related]

  • 29. Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3.
    Benhar I, Pastan I.
    J Biol Chem; 1995 Oct 06; 270(40):23373-80. PubMed ID: 7559495
    [Abstract] [Full Text] [Related]

  • 30. TGF alpha-anti-Tac(Fv)-PE40: a bifunctional toxin cytotoxic for cells with EGF or IL2 receptors.
    Batra JK, Chaudhary VK, FitzGerald D, Pastan I.
    Biochem Biophys Res Commun; 1990 Aug 31; 171(1):1-6. PubMed ID: 2393383
    [Abstract] [Full Text] [Related]

  • 31. Expression and purification of recombinant immunotoxin--a fusion protein stabilizes a single-chain Fv (scFv) in denaturing condition.
    Kim SH.
    Protein Expr Purif; 2003 Jan 31; 27(1):85-9. PubMed ID: 12509988
    [Abstract] [Full Text] [Related]

  • 32. Human breast carcinoma cells express type II IL-4 receptors and are sensitive to antitumor activity of a chimeric IL-4-Pseudomonas exotoxin fusion protein in vitro and in vivo.
    Leland P, Taguchi J, Husain SR, Kreitman RJ, Pastan I, Puri RK.
    Mol Med; 2000 Mar 31; 6(3):165-78. PubMed ID: 10965493
    [Abstract] [Full Text] [Related]

  • 33. Recombinant anti-erbB2 immunotoxins containing Pseudomonas exotoxin.
    Batra JK, Kasprzyk PG, Bird RE, Pastan I, King CR.
    Proc Natl Acad Sci U S A; 1992 Jul 01; 89(13):5867-71. PubMed ID: 1352878
    [Abstract] [Full Text] [Related]

  • 34. Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.
    Benhar I, Padlan EA, Jung SH, Lee B, Pastan I.
    Proc Natl Acad Sci U S A; 1994 Dec 06; 91(25):12051-5. PubMed ID: 7991583
    [Abstract] [Full Text] [Related]

  • 35. Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity.
    Onda M, Nagata S, Tsutsumi Y, Vincent JJ, Wang Q, Kreitman RJ, Lee B, Pastan I.
    Cancer Res; 2001 Jul 01; 61(13):5070-7. PubMed ID: 11431343
    [Abstract] [Full Text] [Related]

  • 36. Construction, expression, and characterization of an anti-tumor immunotoxin containing the human anti-c-Met single-chain antibody and PE38KDEL.
    Liu Z, Feng Z, Zhu X, Xu W, Zhu J, Zhang X, Fan Z, Ji G.
    Immunol Lett; 2013 Jan 01; 149(1-2):30-40. PubMed ID: 23026237
    [Abstract] [Full Text] [Related]

  • 37. [Studies of the expression, purification, renaturation and biologic activity of an anti-CEA immunotoxin].
    Yang H, He D, Chao K, Lin Q, You S, Huang HL.
    Sheng Wu Gong Cheng Xue Bao; 2004 May 01; 20(3):348-51. PubMed ID: 15971603
    [Abstract] [Full Text] [Related]

  • 38. Purification of the IL-2 receptor (TAC) by ligand-affinity chromatography and utilization of the immobilized receptor for receptor-affinity chromatography (RAC) purification of IL-2, mutant IL-2, and IL-2 fusion proteins.
    Smart JE, Familletti PC, Weber DV, Keeney RF, Bailon P.
    J Invest Dermatol; 1990 Jun 01; 94(6 Suppl):158S-163S. PubMed ID: 2351848
    [Abstract] [Full Text] [Related]

  • 39. Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).
    Batra JK, Fitzgerald DJ, Chaudhary VK, Pastan I.
    Mol Cell Biol; 1991 Apr 01; 11(4):2200-5. PubMed ID: 2005905
    [Abstract] [Full Text] [Related]

  • 40. A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin.
    Chaudhary VK, Queen C, Junghans RP, Waldmann TA, FitzGerald DJ, Pastan I.
    Nature; 1989 Jun 01; 339(6223):394-7. PubMed ID: 2498664
    [Abstract] [Full Text] [Related]

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