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243 related items for PubMed ID: 8437592

  • 1. Characterization and expression in Streptomyces lividans of cefD and cefE genes from Nocardia lactamdurans: the organization of the cephamycin gene cluster differs from that in Streptomyces clavuligerus.
    Coque JJ, Martín JF, Liras P.
    Mol Gen Genet; 1993 Jan; 236(2-3):453-8. PubMed ID: 8437592
    [Abstract] [Full Text] [Related]

  • 2. The beta-lactam biosynthesis genes for isopenicillin N epimerase and deacetoxycephalosporin C synthetase are expressed from a single transcript in Streptomyces clavuligerus.
    Kovacevic S, Tobin MB, Miller JR.
    J Bacteriol; 1990 Jul; 172(7):3952-8. PubMed ID: 1694525
    [Abstract] [Full Text] [Related]

  • 3. A gene encoding lysine 6-aminotransferase, which forms the beta-lactam precursor alpha-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans.
    Coque JJ, Liras P, Laiz L, Martín JF.
    J Bacteriol; 1991 Oct; 173(19):6258-64. PubMed ID: 1917857
    [Abstract] [Full Text] [Related]

  • 4. Characterization of the cmcH genes of Nocardia lactamdurans and Streptomyces clavuligerus encoding a functional 3'-hydroxymethylcephem O-carbamoyltransferase for cephamycin biosynthesis.
    Coque JJ, Pérez-Llarena FJ, Enguita FJ, Fuente JL, Martín JF, Liras P.
    Gene; 1995 Aug 30; 162(1):21-7. PubMed ID: 7557411
    [Abstract] [Full Text] [Related]

  • 5. Isolation of deacetoxycephalosporin C from fermentation broths of Penicillium chrysogenum transformants: construction of a new fungal biosynthetic pathway.
    Cantwell C, Beckmann R, Whiteman P, Queener SW, Abraham EP.
    Proc Biol Sci; 1992 Jun 22; 248(1323):283-9. PubMed ID: 1354366
    [Abstract] [Full Text] [Related]

  • 6. Improved expression of a hybrid Streptomyces clavuligerus cefE gene in Penicillium chrysogenum.
    Queener SW, Beckmann RJ, Cantwell CA, Hodges RL, Fisher DL, Dotzlaf JE, Yeh WK, McGilvray D, Greaney M, Rosteck P.
    Ann N Y Acad Sci; 1994 May 02; 721():178-93. PubMed ID: 8010669
    [Abstract] [Full Text] [Related]

  • 7. Cloning and expression of a hybrid Streptomyces clavuligerus cefE gene in Penicillium chrysogenum.
    Cantwell CA, Beckmann RJ, Dotzlaf JE, Fisher DL, Skatrud PL, Yeh WK, Queener SW.
    Curr Genet; 1990 Mar 02; 17(3):213-21. PubMed ID: 2111228
    [Abstract] [Full Text] [Related]

  • 8. Amy as a reporter gene for promoter activity in Nocardia lactamdurans: comparison of promoters of the cephamycin cluster.
    Chary VK, de la Fuente JL, Liras P, Martin JF.
    Appl Environ Microbiol; 1997 Aug 02; 63(8):2977-82. PubMed ID: 9251185
    [Abstract] [Full Text] [Related]

  • 9. Cloning, characterization, and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase.
    Kovacevic S, Weigel BJ, Tobin MB, Ingolia TD, Miller JR.
    J Bacteriol; 1989 Feb 02; 171(2):754-60. PubMed ID: 2644235
    [Abstract] [Full Text] [Related]

  • 10. Glucose regulation of cephamycin biosynthesis in Streptomyces lactamdurans is exerted on the formation of alpha-aminoadipyl-cysteinyl-valine and deacetoxycephalosporin C synthase.
    Cortés J, Liras P, Castro JM, Martín JF.
    J Gen Microbiol; 1986 Jul 02; 132(7):1805-14. PubMed ID: 3794640
    [Abstract] [Full Text] [Related]

  • 11. Cloning and characterization of the isopenicillin N synthase gene of Streptomyces griseus NRRL 3851 and studies of expression and complementation of the cephamycin pathway in Streptomyces clavuligerus.
    García-Domínguez M, Liras P, Martín JF.
    Antimicrob Agents Chemother; 1991 Jan 02; 35(1):44-52. PubMed ID: 1901702
    [Abstract] [Full Text] [Related]

  • 12. The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenum.
    Coque JJ, Martín JF, Calzada JG, Liras P.
    Mol Microbiol; 1991 May 02; 5(5):1125-33. PubMed ID: 1956290
    [Abstract] [Full Text] [Related]

  • 13. Genes for a beta-lactamase, a penicillin-binding protein and a transmembrane protein are clustered with the cephamycin biosynthetic genes in Nocardia lactamdurans.
    Coque JJ, Liras P, Martín JF.
    EMBO J; 1993 Feb 02; 12(2):631-9. PubMed ID: 8440253
    [Abstract] [Full Text] [Related]

  • 14. Cloning and sequencing of the beta-lactam hydroxylase gene (cefF) from Streptomyces clavuligerus: gene duplication may have led to separate hydroxylase and expandase activities in the actinomycetes.
    Kovacevic S, Miller JR.
    J Bacteriol; 1991 Jan 02; 173(1):398-400. PubMed ID: 1987130
    [Abstract] [Full Text] [Related]

  • 15. Characterization of the cefF gene of Nocardia lactamdurans encoding a 3'-methylcephem hydroxylase different from the 7-cephem hydroxylase.
    Coque JJ, Enguita FJ, Cardoza RE, Martín JF, Liras P.
    Appl Microbiol Biotechnol; 1996 Jan 02; 44(5):605-9. PubMed ID: 8703431
    [Abstract] [Full Text] [Related]

  • 16. CcaR is an autoregulatory protein that binds to the ccaR and cefD-cmcI promoters of the cephamycin C-clavulanic acid cluster in Streptomyces clavuligerus.
    Santamarta I, Rodríguez-García A, Pérez-Redondo R, Martín JF, Liras P.
    J Bacteriol; 2002 Jun 02; 184(11):3106-13. PubMed ID: 12003953
    [Abstract] [Full Text] [Related]

  • 17. Cloning and location of a gene governing lysine epsilon-aminotransferase, an enzyme initiating beta-lactam biosynthesis in Streptomyces spp.
    Madduri K, Stuttard C, Vining LC.
    J Bacteriol; 1991 Feb 02; 173(3):985-8. PubMed ID: 1991735
    [Abstract] [Full Text] [Related]

  • 18. Organization and expression in Pseudomonas putida of the gene cluster involved in cephalosporin biosynthesis from Lysobacter lactamgenus YK90.
    Kimura H, Miyashita H, Sumino Y.
    Appl Microbiol Biotechnol; 1996 May 02; 45(4):490-501. PubMed ID: 8737573
    [Abstract] [Full Text] [Related]

  • 19. The nine genes of the Nocardia lactamdurans cephamycin cluster are transcribed into large mRNAs from three promoters, two of them located in a bidirectional promoter region.
    Enguita FJ, Coque JJ, Liras P, Martin JF.
    J Bacteriol; 1998 Oct 02; 180(20):5489-94. PubMed ID: 9765587
    [Abstract] [Full Text] [Related]

  • 20. Localization of the lysine epsilon-aminotransferase (lat) and delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcbAB) genes from Streptomyces clavuligerus and production of lysine epsilon-aminotransferase activity in Escherichia coli.
    Tobin MB, Kovacevic S, Madduri K, Hoskins JA, Skatrud PL, Vining LC, Stuttard C, Miller JR.
    J Bacteriol; 1991 Oct 02; 173(19):6223-9. PubMed ID: 1917855
    [Abstract] [Full Text] [Related]

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