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Journal Abstract Search


132 related items for PubMed ID: 8439517

  • 1. Azasteroids as inhibitors of testosterone 5 alpha-reductase in mammalian skin.
    Mellin TN, Busch RD, Rasmusson GH.
    J Steroid Biochem Mol Biol; 1993 Feb; 44(2):121-31. PubMed ID: 8439517
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and in vitro activity of 17 beta-(N-alkyl/arylformamido)- and 17 beta-[(N-alkyl/aryl)alkyl/arylamido]-4-methyl-4-aza-3-oxo-5 alpha-androstan-3-ones as inhibitors of human 5 alpha-reductases and antagonists of the androgen receptor.
    Li X, Singh SM, Labrie F.
    J Med Chem; 1995 Mar 31; 38(7):1158-73. PubMed ID: 7707319
    [Abstract] [Full Text] [Related]

  • 3. Human osteoblast-like cells express predominantly steroid 5alpha-reductase type 1.
    Issa S, Schnabel D, Feix M, Wolf L, Schaefer HE, Russell DW, Schweikert HU.
    J Clin Endocrinol Metab; 2002 Dec 31; 87(12):5401-7. PubMed ID: 12466325
    [Abstract] [Full Text] [Related]

  • 4. 4-Azasteroidal 5 alpha-reductase inhibitors without affinity for the androgen receptor.
    Liang T, Heiss CE, Cheung AH, Reynolds GF, Rasmusson GH.
    J Biol Chem; 1984 Jan 25; 259(2):734-9. PubMed ID: 6693392
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of 5 alpha-reductase activity and alteration of nuclear testosterone. Dihydrotestosterone ratio in human genital skin fibroblasts.
    Berkovitz GD, Brown TR, Migeon CJ.
    J Androl; 1984 Jan 25; 5(3):171-5. PubMed ID: 6746410
    [Abstract] [Full Text] [Related]

  • 6. 4-Methyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-N-aryl-carboxamides: an approach to combined androgen blockade [5alpha-reductase inhibition with androgen receptor binding in vitro].
    Tolman RL, Sahoo SP, Bakshi RK, Gratale D, Patel G, Patel S, Toney J, Chang B, Harris GS.
    J Steroid Biochem Mol Biol; 1997 Mar 25; 60(5-6):303-9. PubMed ID: 9219921
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of steroid 5 alpha-reductase from human skin fibroblasts by 17 beta-N,N-diethylcarbamoyl-4-methyl-4-aza-5 alpha-androstan-3-one.
    Leshin M, Wilson JD.
    J Steroid Biochem; 1982 Sep 25; 17(3):245-50. PubMed ID: 6957692
    [Abstract] [Full Text] [Related]

  • 8. 19-nor-10-azasteroids: a novel class of inhibitors for human steroid 5alpha-reductases 1 and 2.
    Guarna A, Belle C, Machetti F, Occhiato EG, Payne AH, Cassiani C, Comerci A, Danza G, De Bellis A, Dini S, Marrucci A, Serio M.
    J Med Chem; 1997 Mar 28; 40(7):1112-29. PubMed ID: 9089333
    [Abstract] [Full Text] [Related]

  • 9. The effects of N,N-diethyl-4-methyl-3-oxo-4-aza-5 alpha-androstane-17 beta-carboxamide, a 5 alpha-reductase inhibitor and antiandrogen, on the development of baldness in the stumptail macaque.
    Rittmaster RS, Uno H, Povar ML, Mellin TN, Loriaux DL.
    J Clin Endocrinol Metab; 1987 Jul 28; 65(1):188-93. PubMed ID: 3584395
    [Abstract] [Full Text] [Related]

  • 10. Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque.
    Diani AR, Mulholland MJ, Shull KL, Kubicek MF, Johnson GA, Schostarez HJ, Brunden MN, Buhl AE.
    J Clin Endocrinol Metab; 1992 Feb 28; 74(2):345-50. PubMed ID: 1309834
    [Abstract] [Full Text] [Related]

  • 11. Effect of a 4-methyl-4-aza steroid on androgen metabolism by rat ventral prostate epithelial and stromal cell cultures: selective inhibition of 5 alpha-reductase activity.
    Orlowski J, Clark AF.
    Prostate; 1988 Feb 28; 13(4):289-97. PubMed ID: 3217276
    [Abstract] [Full Text] [Related]

  • 12. Azasteroids: structure-activity relationships for inhibition of 5 alpha-reductase and of androgen receptor binding.
    Rasmusson GH, Reynolds GF, Steinberg NG, Walton E, Patel GF, Liang T, Cascieri MA, Cheung AH, Brooks JR, Berman C.
    J Med Chem; 1986 Nov 28; 29(11):2298-315. PubMed ID: 3783591
    [Abstract] [Full Text] [Related]

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  • 14. Activity of the type 1 5 alpha-reductase exhibits regional differences in isolated sebaceous glands and whole skin.
    Thiboutot D, Harris G, Iles V, Cimis G, Gilliland K, Hagari S.
    J Invest Dermatol; 1995 Aug 28; 105(2):209-14. PubMed ID: 7636302
    [Abstract] [Full Text] [Related]

  • 15. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.
    Hirsch KS, Jones CD, Audia JE, Andersson S, McQuaid L, Stamm NB, Neubauer BL, Pennington P, Toomey RE, Russell DW.
    Proc Natl Acad Sci U S A; 1993 Jun 01; 90(11):5277-81. PubMed ID: 8389478
    [Abstract] [Full Text] [Related]

  • 16. Selective inhibition of prostatic tumor 5 alpha-reductase by a 4-methyl-4-azasteroid.
    Kadohama N, Karr JP, Murphy GP, Sandberg AA.
    Cancer Res; 1984 Nov 01; 44(11):4947-54. PubMed ID: 6488158
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  • 18. Inhibition of the activity of 'basic' 5 alpha-reductase (type 1) detected in DU 145 cells and expressed in insect cells.
    Délos S, Iehlé C, Martin PM, Raynaud JP.
    J Steroid Biochem Mol Biol; 1994 Mar 01; 48(4):347-52. PubMed ID: 8142312
    [Abstract] [Full Text] [Related]

  • 19. Testosterone metabolism in primary cultures of human prostate epithelial cells and fibroblasts.
    Délos S, Carsol JL, Ghazarossian E, Raynaud JP, Martin PM.
    J Steroid Biochem Mol Biol; 1995 Dec 01; 55(3-4):375-83. PubMed ID: 8541234
    [Abstract] [Full Text] [Related]

  • 20. In vivo assay for conversion of testosterone to dihydrotestosterone by rat prostatic steroid 5 alpha-reductase and comparison of two inhibitors.
    Toomey RE, Goode RL, Petrow V, Neubauer BL.
    Prostate; 1991 Dec 01; 19(1):63-72. PubMed ID: 1876537
    [Abstract] [Full Text] [Related]


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