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Journal Abstract Search

168 related items for PubMed ID: 8440739

  • 21.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 22. Alteration of mitochondrial gene expression and disruption of respiratory function by the lipophilic antifolate pyrimethamine in mammalian cells.
    Sprecher H, Barr HM, Slotky JI, Tzukerman M, Eytan GD, Assaraf YG.
    J Biol Chem; 1995 Sep 01; 270(35):20668-76. PubMed ID: 7657646
    [Abstract] [Full Text] [Related]

  • 23.
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  • 24. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells.
    Matherly LH, Barlowe CK, Goldman ID.
    Cancer Res; 1986 Feb 01; 46(2):588-93. PubMed ID: 2416428
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  • 25.
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  • 26. Novel antifolate resistant mutations of Plasmodium falciparum dihydrofolate reductase selected in Escherichia coli.
    Chusacultanachai S, Thiensathit P, Tarnchompoo B, Sirawaraporn W, Yuthavong Y.
    Mol Biochem Parasitol; 2002 Mar 01; 120(1):61-72. PubMed ID: 11849706
    [Abstract] [Full Text] [Related]

  • 27. Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of endogenous DHFR activity, and overexpression of metallothionein II and folate receptor alpha that, upon folate repletion, confer drug resistance to CHL cells.
    Zhu WY, Bunni M, Priest DG, DiCapua JL, Dressler JM, Chen Z, Melera PW.
    J Exp Ther Oncol; 2002 Mar 01; 2(5):264-77. PubMed ID: 12416030
    [Abstract] [Full Text] [Related]

  • 28. Increased activity of a novel low pH folate transporter associated with lipophilic antifolate resistance in chinese hamster ovary cells.
    Assaraf YG, Babani S, Goldman ID.
    J Biol Chem; 1998 Apr 03; 273(14):8106-11. PubMed ID: 9525913
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  • 29.
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  • 30. A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.
    Jansen G, Mauritz R, Drori S, Sprecher H, Kathmann I, Bunni M, Priest DG, Noordhuis P, Schornagel JH, Pinedo HM, Peters GJ, Assaraf YG.
    J Biol Chem; 1998 Nov 13; 273(46):30189-98. PubMed ID: 9804775
    [Abstract] [Full Text] [Related]

  • 31. Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells.
    Affleck JG, Al-Batayneh KM, Neumann K, Cole SP, Walker VK.
    Eur J Pharmacol; 2006 Jan 04; 529(1-3):71-8. PubMed ID: 16325803
    [Abstract] [Full Text] [Related]

  • 32.
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  • 33. Anticancer antifolates: current status and future directions.
    McGuire JJ.
    Curr Pharm Des; 2003 Jan 04; 9(31):2593-613. PubMed ID: 14529544
    [Abstract] [Full Text] [Related]

  • 34. Uptake, cytotoxicity and metabolism of m-azidopyrimethamine and related lipophilic antifolates in SV-K14 human keratinocytes in vivo.
    Baker ND, Griffin RJ, Irwin WJ, Reichert U, Schmidt R.
    Biochem Pharmacol; 1991 Dec 11; 42 Suppl():S39-46. PubMed ID: 1768284
    [Abstract] [Full Text] [Related]

  • 35. Kinetic and molecular properties of the dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant clones of the human malaria parasite Plasmodium falciparum.
    Chen GX, Mueller C, Wendlinger M, Zolg JW.
    Mol Pharmacol; 1987 Apr 11; 31(4):430-7. PubMed ID: 3553892
    [Abstract] [Full Text] [Related]

  • 36.
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  • 37. Different antifolate-resistant L1210 cell variants with either increased or decreased folylpolyglutamate synthetase gene expression at the level of mRNA transcription.
    Roy K, Mitsugi K, Sirlin S, Shane B, Sirotnak FM.
    J Biol Chem; 1995 Nov 10; 270(45):26918-22. PubMed ID: 7592937
    [Abstract] [Full Text] [Related]

  • 38. Changes in enzyme activity and expression of DHFR of Toxoplasma gondii by antifolates.
    Baek EJ, Nam HW.
    Korean J Parasitol; 1998 Sep 10; 36(3):191-8. PubMed ID: 9755590
    [Abstract] [Full Text] [Related]

  • 39. Cytotoxicity of trimetrexate against antifolate-resistant human T-cell leukemia cell lines developed in oxidized or reduced folate.
    Miyachi H, Takemura Y, Kobayashi H, Ando Y.
    Jpn J Cancer Res; 1997 Sep 10; 88(9):900-6. PubMed ID: 9369939
    [Abstract] [Full Text] [Related]

  • 40. Cross-resistance to the lipid-soluble antifolate trimetrexate in human carcinoma cells with the multidrug-resistant phenotype.
    Assaraf YG, Molina A, Schimke RT.
    J Natl Cancer Inst; 1989 Feb 15; 81(4):290-4. PubMed ID: 2521520
    [Abstract] [Full Text] [Related]

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