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Journal Abstract Search

168 related items for PubMed ID: 8440739

  • 41. A single point mutation in Drosophila dihydrofolate reductase confers methotrexate resistance to a transgenic CHO cell line.
    Neumann K, Al-Batayneh KM, Kuiper MJ, Parsons-Sheldrake J, Tyshenko MG, Flintoff WF, Cole SP, Walker VK.
    Genome; 2003 Aug; 46(4):707-15. PubMed ID: 12897877
    [Abstract] [Full Text] [Related]

  • 42. The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis.
    Assaraf YG.
    Drug Resist Updat; 2006 Aug; 9(4-5):227-46. PubMed ID: 17092765
    [Abstract] [Full Text] [Related]

  • 43. Antifolate drug interactions: enhancement of growth inhibition due to the antipurine 5,10-dideazatetrahydrofolic acid by the lipophilic dihydrofolate reductase inhibitors metoprine and trimetrexate.
    Galivan J, Nimec Z, Rhee M, Boschelli D, Oronsky AL, Kerwar SS.
    Cancer Res; 1988 May 01; 48(9):2421-5. PubMed ID: 2965613
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  • 45. Heterologous expression and characterization of the bifunctional dihydrofolate reductase-thymidylate synthase enzyme of Toxoplasma gondii.
    Trujillo M, Donald RG, Roos DS, Greene PJ, Santi DV.
    Biochemistry; 1996 May 21; 35(20):6366-74. PubMed ID: 8639582
    [Abstract] [Full Text] [Related]

  • 46. Variable expression of RFC1 in human leukemia cell lines resistant to antifolates.
    Kobayashi H, Takemura Y, Ohnuma T.
    Cancer Lett; 1998 Feb 27; 124(2):135-42. PubMed ID: 9500202
    [Abstract] [Full Text] [Related]

  • 47. Biochemical pharmacology of the lipophilic antifolate, trimetrexate.
    Jackson RC, Fry DW, Boritzki TJ, Besserer JA, Leopold WR, Sloan BJ, Elslager EF.
    Adv Enzyme Regul; 1984 Feb 27; 22():187-206. PubMed ID: 6236675
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  • 48. Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression.
    Mayer-Kuckuk P, Banerjee D, Malhotra S, Doubrovin M, Iwamoto M, Akhurst T, Balatoni J, Bornmann W, Finn R, Larson S, Fong Y, Gelovani Tjuvajev J, Blasberg R, Bertino JR.
    Proc Natl Acad Sci U S A; 2002 Mar 19; 99(6):3400-5. PubMed ID: 11891321
    [Abstract] [Full Text] [Related]

  • 49. Towards species-specific antifolates.
    Chan DC, Anderson AC.
    Curr Med Chem; 2006 Mar 19; 13(4):377-98. PubMed ID: 16475929
    [Abstract] [Full Text] [Related]

  • 50. Trypanosomal dihydrofolate reductase reveals natural antifolate resistance.
    Vanichtanankul J, Taweechai S, Yuvaniyama J, Vilaivan T, Chitnumsub P, Kamchonwongpaisan S, Yuthavong Y.
    ACS Chem Biol; 2011 Sep 16; 6(9):905-11. PubMed ID: 21650210
    [Abstract] [Full Text] [Related]

  • 51. Kinetic properties of dihydrofolate reductase from wild-type and mutant Plasmodium vivax expressed in Escherichia coli.
    Tahar R, de Pécoulas PE, Basco LK, Chiadmi M, Mazabraud A.
    Mol Biochem Parasitol; 2001 Apr 06; 113(2):241-9. PubMed ID: 11295178
    [Abstract] [Full Text] [Related]

  • 52. The toxicity of antifolates in Babesia bovis.
    Nott SE, Bagnara AS.
    Int J Parasitol; 1993 May 06; 23(3):399-402. PubMed ID: 8359989
    [Abstract] [Full Text] [Related]

  • 53. Dihydrofolate reductase binding and cellular uptake of nonpolyglutamatable antifolates: correlates of cytotoxicity toward methotrexate-sensitive and -resistant human head and neck squamous carcinoma cells.
    Chen G, Wright JE, Rosowsky A.
    Mol Pharmacol; 1995 Oct 06; 48(4):758-65. PubMed ID: 7476904
    [Abstract] [Full Text] [Related]

  • 54. Homology modeling of wild type and pyrimethamine/cycloguanil-cross resistant mutant type Plasmodium falciparum dihydrofolate reductase. A model for antimalarial chemotherapy resistance.
    Santos-Filho OA, de Alencastro RB, Figueroa-Villar JD.
    Biophys Chem; 2001 Jul 24; 91(3):305-17. PubMed ID: 11551441
    [Abstract] [Full Text] [Related]

  • 55. Mutations leading to antifolate resistance in Chinese hamster ovary cells after exposure to the alkylating agent ethylmethanesulfonate.
    Fanin R, Banerjee D, Volkenandt M, Waltham M, Li WW, Dicker AP, Schweitzer BI, Bertino JR.
    Mol Pharmacol; 1993 Jul 24; 44(1):13-21. PubMed ID: 8341268
    [Abstract] [Full Text] [Related]

  • 56. Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application.
    McIvor RS.
    Bone Marrow Transplant; 1996 Dec 24; 18 Suppl 3():S50-4. PubMed ID: 8971409
    [Abstract] [Full Text] [Related]

  • 57. Mutagenesis of dihydrofolate reductase from Plasmodium falciparum: analysis in Saccharomyces cerevisiae of triple mutant alleles resistant to pyrimethamine or WR99210.
    Ferlan JT, Mookherjee S, Okezie IN, Fulgence L, Sibley CH.
    Mol Biochem Parasitol; 2001 Mar 24; 113(1):139-50. PubMed ID: 11254962
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  • 59. Comparison of the protection of cells from antifolates by transduced human dihydrofolate reductase mutants.
    Patel M, Sleep SE, Lewis WS, Spencer HT, Mareya SM, Sorrentino BP, Blakley RL.
    Hum Gene Ther; 1997 Nov 20; 8(17):2069-77. PubMed ID: 9414255
    [Abstract] [Full Text] [Related]

  • 60. Use of the Escherichia coli chromosomal DHFR gene as selection marker in mammalian cells.
    Asselbergs FA, Widmer R.
    J Biotechnol; 1995 Dec 01; 43(2):133-8. PubMed ID: 8562018
    [Abstract] [Full Text] [Related]

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