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202 related items for PubMed ID: 8443814

  • 1. Increased NAD(P)H:(quinone-acceptor)oxidoreductase activity is associated with density-dependent growth inhibition of normal but not transformed cells.
    Schlager JJ, Hoerl BJ, Riebow J, Scott DP, Gasdaska P, Scott RE, Powis G.
    Cancer Res; 1993 Mar 15; 53(6):1338-42. PubMed ID: 8443814
    [Abstract] [Full Text] [Related]

  • 2. Over-expression of DT-diaphorase in transfected NIH 3T3 cells does not lead to increased anticancer quinone drug sensitivity: a questionable role for the enzyme as a target for bioreductively activated anticancer drugs.
    Powis G, Gasdaska PY, Gallegos A, Sherrill K, Goodman D.
    Anticancer Res; 1995 Mar 15; 15(4):1141-5. PubMed ID: 7653992
    [Abstract] [Full Text] [Related]

  • 3. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A.
    Cancer Chemother Pharmacol; 2002 Feb 15; 49(2):101-10. PubMed ID: 11862423
    [Abstract] [Full Text] [Related]

  • 4. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D, Gibson NW, Preusch PC, Ross D.
    Cancer Res; 1990 Nov 15; 50(22):7293-300. PubMed ID: 2121335
    [Abstract] [Full Text] [Related]

  • 5. Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase.
    Wu K, Knox R, Sun XZ, Joseph P, Jaiswal AK, Zhang D, Deng PS, Chen S.
    Arch Biochem Biophys; 1997 Nov 15; 347(2):221-8. PubMed ID: 9367528
    [Abstract] [Full Text] [Related]

  • 6. A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent.
    Winski SL, Hargreaves RH, Butler J, Ross D.
    Clin Cancer Res; 1998 Dec 15; 4(12):3083-8. PubMed ID: 9865924
    [Abstract] [Full Text] [Related]

  • 7. Cellular kinetics of induction by oltipraz and its keto derivative of detoxication enzymes in human colon adenocarcinoma cells.
    O'Dwyer PJ, Clayton M, Halbherr T, Myers CB, Yao Ks.
    Clin Cancer Res; 1997 May 15; 3(5):783-91. PubMed ID: 9815750
    [Abstract] [Full Text] [Related]

  • 8. Demonstration of the activation of prodrug CB 1954 using human DT-diaphorase mutant Q104Y-transfected MDA-MB-231 cells and mouse xenograft model.
    Wu K, Eng E, Knox R, Chen S.
    Arch Biochem Biophys; 2001 Jan 01; 385(1):203-8. PubMed ID: 11361019
    [Abstract] [Full Text] [Related]

  • 9. The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
    Qiu XB, Cadenas E.
    Arch Biochem Biophys; 1997 Oct 15; 346(2):241-51. PubMed ID: 9343371
    [Abstract] [Full Text] [Related]

  • 10. Cell cycle variation in 125I-labeled epidermal growth factor binding in chemically transformed cells.
    Robinson RA, Branum EL, Volkenant ME, Moses HL.
    Cancer Res; 1982 Jul 15; 42(7):2633-8. PubMed ID: 6979383
    [Abstract] [Full Text] [Related]

  • 11. Induction of DT-diaphorase in cancer chemoprevention and chemotherapy.
    Begleiter A, Leith MK, Curphey TJ, Doherty GP.
    Oncol Res; 1997 Jul 15; 9(6-7):371-82. PubMed ID: 9406243
    [Abstract] [Full Text] [Related]

  • 12. Activity profile of the novel aziridinylbenzoquinones MeDZQ and RH1 in human tumour xenografts.
    Cummings J, Ritchie A, Butler J, Ward TH, Langdon S.
    Anticancer Res; 2003 Jul 15; 23(5A):3979-83. PubMed ID: 14666706
    [Abstract] [Full Text] [Related]

  • 13. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under hypoxia.
    Begleiter A, Robotham E, Leith MK.
    Mol Pharmacol; 1992 Apr 15; 41(4):677-82. PubMed ID: 1373799
    [Abstract] [Full Text] [Related]

  • 14. An alternatively spliced form of NQO1 (DT-diaphorase) messenger RNA lacking the putative quinone substrate binding site is present in human normal and tumor tissues.
    Gasdaska PY, Fisher H, Powis G.
    Cancer Res; 1995 Jun 15; 55(12):2542-7. PubMed ID: 7780966
    [Abstract] [Full Text] [Related]

  • 15. Involvement of activator protein-1 and nuclear factor-kappaB transcription factors in the control of the DT-diaphorase expression induced by mitomycin C treatment.
    Yao KS, Hageboutros A, Ford P, O'Dwyer PJ.
    Mol Pharmacol; 1997 Mar 15; 51(3):422-30. PubMed ID: 9058597
    [Abstract] [Full Text] [Related]

  • 16. Cigarette smoking is a determinant of DT-diaphorase gene expression in human non-small cell lung carcinoma.
    Gasdaska PY, Powis G, Hyman P, Fisher H.
    Cancer Res; 1993 Nov 15; 53(22):5458-61. PubMed ID: 8221686
    [Abstract] [Full Text] [Related]

  • 17. Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase.
    Wang X, Doherty GP, Leith MK, Curphey TJ, Begleiter A.
    Br J Cancer; 1999 Jun 15; 80(8):1223-30. PubMed ID: 10376975
    [Abstract] [Full Text] [Related]

  • 18. [Mitomycin C and its bioreduction: relevance of NAD(P)H: quinone oxidoreductase activity to mitomycin C-induced DNA damage and cytotoxicity].
    Nishiyama M, Saeki S, Aogi K, Hirabayashi N, Toge T.
    Gan To Kagaku Ryoho; 1993 Jun 15; 20(8):1037-41. PubMed ID: 7685584
    [Abstract] [Full Text] [Related]

  • 19. Expression and activity of NAD(P)H:quinone oxidoreductase (NMO1) in human osteoblastic cells.
    Collin P, Lomri A, Marie PJ.
    Bone; 2001 Jan 15; 28(1):9-13. PubMed ID: 11165937
    [Abstract] [Full Text] [Related]

  • 20. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under acidic conditions.
    Begleiter A, Leith MK.
    Mol Pharmacol; 1993 Jul 15; 44(1):210-5. PubMed ID: 8341273
    [Abstract] [Full Text] [Related]

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