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303 related items for PubMed ID: 8444418

  • 1. Accumulation of organic anion in intracellular vesicles of cultured rat hepatocytes is mediated by the canalicular multispecific organic anion transporter.
    Oude Elferink RP, Bakker CT, Roelofsen H, Middelkoop E, Ottenhoff R, Heijn M, Jansen PL.
    Hepatology; 1993 Mar; 17(3):434-44. PubMed ID: 8444418
    [Abstract] [Full Text] [Related]

  • 2. Redistribution of canalicular organic anion transport activity in isolated and cultured rat hepatocytes.
    Roelofsen H, Bakker CT, Schoemaker B, Heijn M, Jansen PL, Elferink RP.
    Hepatology; 1995 Jun; 21(6):1649-57. PubMed ID: 7768511
    [Abstract] [Full Text] [Related]

  • 3. Defective ATP-dependent bile canalicular transport of organic anions in mutant (TR-) rats with conjugated hyperbilirubinemia.
    Kitamura T, Jansen P, Hardenbrook C, Kamimoto Y, Gatmaitan Z, Arias IM.
    Proc Natl Acad Sci U S A; 1990 May; 87(9):3557-61. PubMed ID: 2333302
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of glutathione-conjugate secretion from isolated hepatocytes by dipolar bile acids and other organic anions.
    Oude Elferink RP, Ottenhoff R, Radominska A, Hofmann AF, Kuipers F, Jansen PL.
    Biochem J; 1991 Feb 15; 274 ( Pt 1)(Pt 1):281-6. PubMed ID: 2001244
    [Abstract] [Full Text] [Related]

  • 5. Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione.
    Paulusma CC, van Geer MA, Evers R, Heijn M, Ottenhoff R, Borst P, Oude Elferink RP.
    Biochem J; 1999 Mar 01; 338 ( Pt 2)(Pt 2):393-401. PubMed ID: 10024515
    [Abstract] [Full Text] [Related]

  • 6. ATP-dependent organic anion transport system in normal and TR- rat liver canalicular membranes.
    Nishida T, Hardenbrook C, Gatmaitan Z, Arias IM.
    Am J Physiol; 1992 Apr 01; 262(4 Pt 1):G629-35. PubMed ID: 1566846
    [Abstract] [Full Text] [Related]

  • 7. Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes.
    Mayer R, Kartenbeck J, Büchler M, Jedlitschky G, Leier I, Keppler D.
    J Cell Biol; 1995 Oct 01; 131(1):137-50. PubMed ID: 7559771
    [Abstract] [Full Text] [Related]

  • 8. Different pathways of canalicular secretion of sulfated and non-sulfated fluorescent bile acids: a study in isolated hepatocyte couplets and TR- rats.
    Mills CO, Milkiewicz P, Müller M, Roma MG, Havinga R, Coleman R, Kuipers F, Jansen PL, Elias E.
    J Hepatol; 1999 Oct 01; 31(4):678-84. PubMed ID: 10551392
    [Abstract] [Full Text] [Related]

  • 9. Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver.
    Beuers U, Bilzer M, Chittattu A, Kullak-Ublick GA, Keppler D, Paumgartner G, Dombrowski F.
    Hepatology; 2001 May 01; 33(5):1206-16. PubMed ID: 11343250
    [Abstract] [Full Text] [Related]

  • 10. Participation of the multispecific organic anion transporter in hepatobiliary excretion of glutathione S-conjugates, drugs and other xenobiotics.
    Makowski P, Pikuła S.
    Pol J Pharmacol; 1997 May 01; 49(6):387-94. PubMed ID: 9566041
    [Abstract] [Full Text] [Related]

  • 11. Species differences in the transport activity for organic anions across the bile canalicular membrane.
    Ishizuka H, Konno K, Shiina T, Naganuma H, Nishimura K, Ito K, Suzuki H, Sugiyama Y.
    J Pharmacol Exp Ther; 1999 Sep 01; 290(3):1324-30. PubMed ID: 10454510
    [Abstract] [Full Text] [Related]

  • 12. Cyclic AMP stimulates sorting of the canalicular organic anion transporter (Mrp2/cMoat) to the apical domain in hepatocyte couplets.
    Roelofsen H, Soroka CJ, Keppler D, Boyer JL.
    J Cell Sci; 1998 Apr 01; 111 ( Pt 8)():1137-45. PubMed ID: 9512509
    [Abstract] [Full Text] [Related]

  • 13. Transport characteristics of three fluorescent conjugated bile acid analogs in isolated rat hepatocytes and couplets.
    Maglova LM, Jackson AM, Meng XJ, Carruth MW, Schteingart CD, Ton-Nu HT, Hofmann AF, Weinman SA.
    Hepatology; 1995 Aug 01; 22(2):637-47. PubMed ID: 7635434
    [Abstract] [Full Text] [Related]

  • 14. Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats.
    Fernández-Checa JC, Takikawa H, Horie T, Ookhtens M, Kaplowitz N.
    J Biol Chem; 1992 Jan 25; 267(3):1667-73. PubMed ID: 1730711
    [Abstract] [Full Text] [Related]

  • 15. Preserved organic anion transport in mutant TR- rats with a hepatobiliary secretion defect.
    Jansen PL, van Klinken JW, van Gelder M, Ottenhoff R, Elferink RP.
    Am J Physiol; 1993 Sep 25; 265(3 Pt 1):G445-52. PubMed ID: 8214066
    [Abstract] [Full Text] [Related]

  • 16. Impaired activity of the bile canalicular organic anion transporter (Mrp2/cmoat) is not the main cause of ethinylestradiol-induced cholestasis in the rat.
    Koopen NR, Wolters H, Havinga R, Vonk RJ, Jansen PL, Müller M, Kuipers F.
    Hepatology; 1998 Feb 25; 27(2):537-45. PubMed ID: 9462655
    [Abstract] [Full Text] [Related]

  • 17. Primary active transport of organic anions on bile canalicular membrane in humans.
    Niinuma K, Kato Y, Suzuki H, Tyson CA, Weizer V, Dabbs JE, Froehlich R, Green CE, Sugiyama Y.
    Am J Physiol; 1999 May 25; 276(5):G1153-64. PubMed ID: 10330006
    [Abstract] [Full Text] [Related]

  • 18. Two distinct mechanisms for bilirubin glucuronide transport by rat bile canalicular membrane vesicles. Demonstration of defective ATP-dependent transport in rats (TR-) with inherited conjugated hyperbilirubinemia.
    Nishida T, Gatmaitan Z, Roy-Chowdhry J, Arias IM.
    J Clin Invest; 1992 Nov 25; 90(5):2130-5. PubMed ID: 1430236
    [Abstract] [Full Text] [Related]

  • 19. Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuronide.
    Niinuma K, Takenaka O, Horie T, Kobayashi K, Kato Y, Suzuki H, Sugiyama Y.
    J Pharmacol Exp Ther; 1997 Aug 25; 282(2):866-72. PubMed ID: 9262353
    [Abstract] [Full Text] [Related]

  • 20. ATP-dependent multispecific organic anion transport system in rat erythrocyte membrane vesicles.
    Heijn M, Oude Elferink RP, Jansen PL.
    Am J Physiol; 1992 Jan 25; 262(1 Pt 1):C104-10. PubMed ID: 1531100
    [Abstract] [Full Text] [Related]


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