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273 related items for PubMed ID: 8449930

  • 1. Transfected m2 muscarinic acetylcholine receptors couple to G alpha i2 and G alpha i3 in Chinese hamster ovary cells. Activation and desensitization of the phospholipase C signaling pathway.
    Dell'Acqua ML, Carroll RC, Peralta EG.
    J Biol Chem; 1993 Mar 15; 268(8):5676-85. PubMed ID: 8449930
    [Abstract] [Full Text] [Related]

  • 2. Heterotrimeric G proteins containing G alpha i3 regulate multiple effector enzymes in the same cell. Activation of phospholipases C and A2 and inhibition of adenylyl cyclase.
    Hunt TW, Carroll RC, Peralta EG.
    J Biol Chem; 1994 Nov 25; 269(47):29565-70. PubMed ID: 7961942
    [Abstract] [Full Text] [Related]

  • 3. Coincidence detection at the level of phospholipase C activation mediated by the m4 muscarinic acetylcholine receptor.
    Carroll RC, Morielli AD, Peralta EG.
    Curr Biol; 1995 May 01; 5(5):536-44. PubMed ID: 7583103
    [Abstract] [Full Text] [Related]

  • 4. Coupling of muscarinic m1, m2 and m3 acetylcholine receptors, expressed in Chinese hamster ovary cells, to pertussis toxin-sensitive/insensitive guanine nucleotide-binding proteins.
    Burford NT, Tobin AB, Nahorski SR.
    Eur J Pharmacol; 1995 Apr 28; 289(2):343-51. PubMed ID: 7621908
    [Abstract] [Full Text] [Related]

  • 5. Complex involvement of pertussis toxin-sensitive G proteins in the regulation of type 1alpha metabotropic glutamate receptor signaling in baby hamster kidney cells.
    Hermans E, Saunders R, Selkirk JV, Mistry R, Nahorski SR, Challiss RA.
    Mol Pharmacol; 2000 Aug 28; 58(2):352-60. PubMed ID: 10908303
    [Abstract] [Full Text] [Related]

  • 6. G protein subunits and the stimulation of phospholipase C by Gs-and Gi-coupled receptors: Lack of receptor selectivity of Galpha(16) and evidence for a synergic interaction between Gbeta gamma and the alpha subunit of a receptor activated G protein.
    Zhu X, Birnbaumer L.
    Proc Natl Acad Sci U S A; 1996 Apr 02; 93(7):2827-31. PubMed ID: 8610126
    [Abstract] [Full Text] [Related]

  • 7. Delineation of muscarinic receptor domains conferring selectivity of coupling to guanine nucleotide-binding proteins and second messengers.
    Wess J, Bonner TI, Dörje F, Brann MR.
    Mol Pharmacol; 1990 Oct 02; 38(4):517-23. PubMed ID: 2172767
    [Abstract] [Full Text] [Related]

  • 8. Differential calcium signalling by m2 and m3 muscarinic acetylcholine receptors in a single cell type.
    Schmidt M, Bienek C, van Koppen CJ, Michel MC, Jakobs KH.
    Naunyn Schmiedebergs Arch Pharmacol; 1995 Nov 02; 352(5):469-76. PubMed ID: 8751074
    [Abstract] [Full Text] [Related]

  • 9. m3 Muscarinic receptor-induced and Gi-mediated heterologous potentiation of phospholipase C stimulation: role of phosphoinositide synthesis.
    Schmidt M, Nehls C, Rümenapp U, Jakobs KH.
    Mol Pharmacol; 1996 Oct 02; 50(4):1038-46. PubMed ID: 8863852
    [Abstract] [Full Text] [Related]

  • 10. Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors.
    Wylie PG, Challiss RA, Blank JL.
    Biochem J; 1999 Mar 15; 338 ( Pt 3)(Pt 3):619-28. PubMed ID: 10051431
    [Abstract] [Full Text] [Related]

  • 11. Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11.
    Offermanns S, Wieland T, Homann D, Sandmann J, Bombien E, Spicher K, Schultz G, Jakobs KH.
    Mol Pharmacol; 1994 May 15; 45(5):890-8. PubMed ID: 8190105
    [Abstract] [Full Text] [Related]

  • 12. The m2 muscarinic acetylcholine receptors are coupled to multiple signaling pathways via pertussis toxin-sensitive guanine nucleotide regulatory proteins.
    Lai J, Waite SL, Bloom JW, Yamamura HI, Roeske WR.
    J Pharmacol Exp Ther; 1991 Sep 15; 258(3):938-44. PubMed ID: 1653846
    [Abstract] [Full Text] [Related]

  • 13. Galpha(i2), Galpha(i3)and Galpha(o) are all required for normal muscarinic inhibition of the cardiac calcium channels in nodal/atrial-like cultured cardiocytes.
    Ye C, Sowell MO, Vassilev PM, Milstone DS, Mortensen RM.
    J Mol Cell Cardiol; 1999 Sep 15; 31(9):1771-81. PubMed ID: 10471359
    [Abstract] [Full Text] [Related]

  • 14. Phospholipase C, protein kinase C, Ca(2+)/calmodulin-dependent protein kinase II, and tyrosine phosphorylation are involved in carbachol-induced phospholipase D activation in Chinese hamster ovary cells expressing muscarinic acetylcholine receptor of Caenorhabditis elegans.
    Min DS, Cho NJ, Yoon SH, Lee YH, Hahn SJ, Lee KH, Kim MS, Jo YH.
    J Neurochem; 2000 Jul 15; 75(1):274-81. PubMed ID: 10854271
    [Abstract] [Full Text] [Related]

  • 15. Rapid and persistent desensitization of m3 muscarinic acetylcholine receptor-stimulated phospholipase D. Concomitant sensitization of phospholipase C.
    Schmidt M, Fasselt B, Rümenapp U, Bienek C, Wieland T, van Koppen CJ, Jakobs KH.
    J Biol Chem; 1995 Aug 25; 270(34):19949-56. PubMed ID: 7650010
    [Abstract] [Full Text] [Related]

  • 16. Strong and persistent activation of inositol lipid breakdown induces early mitogenic events but not Go to S phase progression in hamster fibroblasts. Comparison of thrombin and carbachol action in cells expressing M1 muscarinic acetylcholine receptors.
    Seuwen K, Kahan C, Hartmann T, Pouyssegur J.
    J Biol Chem; 1990 Dec 25; 265(36):22292-9. PubMed ID: 2176213
    [Abstract] [Full Text] [Related]

  • 17. Hamster alpha 1B-adrenergic receptor directly activates Gs in the transfected Chinese hamster ovary cells.
    Horie K, Itoh H, Tsujimoto G.
    Mol Pharmacol; 1995 Sep 25; 48(3):392-400. PubMed ID: 7565618
    [Abstract] [Full Text] [Related]

  • 18. Differential coupling of m1, m2 and m3 muscarinic receptor subtypes to inositol 1,4,5-trisphosphate and adenosine 3',5'-cyclic monophosphate accumulation in Chinese hamster ovary cells.
    Burford NT, Tobin AB, Nahorski SR.
    J Pharmacol Exp Ther; 1995 Jul 25; 274(1):134-42. PubMed ID: 7616390
    [Abstract] [Full Text] [Related]

  • 19. Distinct internalization of M2 muscarinic acetylcholine receptors confers selective and long-lasting desensitization of signaling to phospholipase C.
    Krudewig R, Langer B, Vögler O, Markschies N, Erl M, Jakobs KH, van Koppen CJ.
    J Neurochem; 2000 Apr 25; 74(4):1721-30. PubMed ID: 10737631
    [Abstract] [Full Text] [Related]

  • 20. Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs.
    Eason MG, Kurose H, Holt BD, Raymond JR, Liggett SB.
    J Biol Chem; 1992 Aug 05; 267(22):15795-801. PubMed ID: 1322406
    [Abstract] [Full Text] [Related]

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