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Journal Abstract Search

131 related items for PubMed ID: 8459396

  • 1. Centrally acting serotonergic agents. Synthesis and structure-activity relationships of C-1- or C-3-substituted derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin.
    Lin CH, Haadsma-Svensson SR, Lahti RA, McCall RB, Piercey MF, Schreur PJ, VonVoigtlander PF, Chidester CG.
    J Med Chem; 1993 Mar 19; 36(6):671-82. PubMed ID: 8459396
    [Abstract] [Full Text] [Related]

  • 2. Centrally acting serotonergic and dopaminergic agents. 2. Synthesis and structure-activity relationships of 2,3,3a,4,9,9a-hexahydro-1H-benz[f]indole derivatives.
    Lin CH, Haadsma-Svensson SR, Phillips G, Lahti RA, McCall RB, Piercey MF, Schreur PJ, Von Voigtlander PF, Smith MW, Chidester CG.
    J Med Chem; 1993 Apr 16; 36(8):1069-83. PubMed ID: 8097538
    [Abstract] [Full Text] [Related]

  • 3. Centrally acting serotonergic and dopaminergic agents. 1. Synthesis and structure-activity relationships of 2,3,3a,4,5,9b-hexahydro-1H-benz[e]indole derivatives.
    Lin CH, Haadsma-Svensson SR, Lahti RA, McCall RB, Piercey MF, Schreur PJ, Von Voigtlander PF, Smith MW, Chidester CG.
    J Med Chem; 1993 Apr 16; 36(8):1053-68. PubMed ID: 8097537
    [Abstract] [Full Text] [Related]

  • 4. Differential serotoninergic and dopaminergic activities of the (R)- and the (S)-enantiomers of 2-(di-n-propylamino)tetralin.
    Yu H, Liu Y, Malmberg A, Mohell N, Hacksell U, Lewander T.
    Eur J Pharmacol; 1996 May 15; 303(3):151-62. PubMed ID: 8813561
    [Abstract] [Full Text] [Related]

  • 5. Interactions of (+)- and (-)-8- and 7-hydroxy-2-(di-n-propylamino)tetralin at human (h)D3, hD2 and h serotonin1A receptors and their modulation of the activity of serotoninergic and dopaminergic neurones in rats.
    Lejeune F, Newman-Tancredi A, Audinot V, Millan MJ.
    J Pharmacol Exp Ther; 1997 Mar 15; 280(3):1241-9. PubMed ID: 9067310
    [Abstract] [Full Text] [Related]

  • 6. (S)- and (R)-8-(di-n-propylamino)-6,7,8,9-tetrahydro-3H-benz[e]indole-1- carbaldehyde: a new class of orally active 5-HT1A-receptor agonists.
    Stjernlöf P, Gullme M, Elebring T, Andersson B, Wikström H, Lagerquist S, Svensson K, Ekman A, Carlsson A, Sundell S.
    J Med Chem; 1993 Jul 23; 36(15):2059-65. PubMed ID: 8340910
    [Abstract] [Full Text] [Related]

  • 7. 2-(Alkylamino)tetralin derivatives: interaction with 5-HT1A serotonin binding sites.
    Naiman N, Lyon RA, Bullock AE, Rydelek LT, Titeler M, Glennon RA.
    J Med Chem; 1989 Jan 23; 32(1):253-6. PubMed ID: 2521252
    [Abstract] [Full Text] [Related]

  • 8. (+)-cis-8-Hydroxy-1-methyl-2-(di-n-propylamino)tetralin: a potent and highly stereoselective 5-hydroxytryptamine receptor agonist.
    Arvidsson LE, Johansson AM, Hacksell U, Nilsson JL, Svensson K, Hjorth S, Magnusson T, Carlsson A, Andersson B, Wikström H.
    J Med Chem; 1987 Nov 23; 30(11):2105-9. PubMed ID: 2959776
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of novel 5-substituted 3-amino-3,4-dihydro-2H-1-benzopyran derivatives and their interactions with the 5-HT1A receptor.
    Hammarberg E, Nordvall G, Leideborg R, Nylöf M, Hanson S, Johansson L, Thorberg SO, Tolf BR, Jerning E, Svantesson GT, Mohell N, Ahlgren C, Westlind-Danielsson A, Csöregh I, Johansson R.
    J Med Chem; 2000 Jul 27; 43(15):2837-50. PubMed ID: 10956192
    [Abstract] [Full Text] [Related]

  • 10. Central dopaminergic and 5-hydroxytryptaminergic effects of C3-methylated derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin.
    Mellin C, Björk L, Karlén A, Johansson AM, Sundell S, Kenne L, Nelson DL, Andén NE, Hacksell U.
    J Med Chem; 1988 Jun 27; 31(6):1130-40. PubMed ID: 2967376
    [Abstract] [Full Text] [Related]

  • 11. Derivatives of (R)- and (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: synthesis and interactions with 5-HT1A receptors.
    Höök BB, Cortizo L, Johansson AM, Westlind-Danielsson A, Mohell N, Hacksell U.
    J Med Chem; 1996 Sep 27; 39(20):4036-43. PubMed ID: 8831769
    [Abstract] [Full Text] [Related]

  • 12. A series of N4-imidoethyl derivatives of 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine as 5-HT1A receptor ligands: synthesis and structure-affinity relationships.
    van Steen BJ, van Wijngaarden I, Tulp MT, Soudijn W.
    J Med Chem; 1995 Oct 13; 38(21):4303-8. PubMed ID: 7473558
    [Abstract] [Full Text] [Related]

  • 13. 2-aminotetralin-derived substituted benzamides with mixed dopamine D2, D3, and serotonin 5-HT1A receptor binding properties: a novel class of potential atypical antipsychotic agents.
    Homan EJ, Copinga S, Elfström L, van der Veen T, Hallema JP, Mohell N, Unelius L, Johansson R, Wikström HV, Grol CJ.
    Bioorg Med Chem; 1998 Nov 13; 6(11):2111-26. PubMed ID: 9881101
    [Abstract] [Full Text] [Related]

  • 14. Derivatives of cis-2-amino-8-hydroxy-1-methyltetralin: mixed 5-HT1A-receptor agonists and dopamine D2-receptor antagonists.
    Liu Y, Yu H, Mohell N, Nordvall G, Lewander T, Hacksell U.
    J Med Chem; 1995 Jan 06; 38(1):150-60. PubMed ID: 7530773
    [Abstract] [Full Text] [Related]

  • 15. (R)- and (S)-8-acetyl-2-(dipropylamino)tetralin (LY-41): two novel 5-HT1A receptor agonists.
    Yu H, Liu Y, Hacksell U, Lewander T.
    Eur J Pharmacol; 1993 Jan 26; 231(1):69-76. PubMed ID: 8444282
    [Abstract] [Full Text] [Related]

  • 16. Intrinsic activity of enantiomers of 8-hydroxy-2-(di-n-propylamino)tetralin and its analogs at 5-hydroxytryptamine1A receptors that are negatively coupled to adenylate cyclase.
    Cornfield LJ, Lambert G, Arvidsson LE, Mellin C, Vallgårda J, Hacksell U, Nelson DL.
    Mol Pharmacol; 1991 Jun 26; 39(6):780-7. PubMed ID: 1828859
    [Abstract] [Full Text] [Related]

  • 17. Differential regulation of somatodendritic serotonin 5-HT1A receptors by 2-week treatments with the selective agonists alnespirone (S-20499) and 8-hydroxy-2-(Di-n-propylamino)tetralin: microdialysis and autoradiographic studies in rat brain.
    Casanovas JM, Vilaró MT, Mengod G, Artigas F.
    J Neurochem; 1999 Jan 26; 72(1):262-72. PubMed ID: 9886078
    [Abstract] [Full Text] [Related]

  • 18. Orally active central dopamine and serotonin receptor ligands: 5-, 6-, 7-, and 8-[[trifluoromethyl)sulfonyl]oxy]-2-(di-n-propylamino)tetralins and the formation of active metabolites in vivo.
    Sonesson C, Boije M, Svensson K, Ekman A, Carlsson A, Romero AG, Martin IJ, Duncan JN, King LJ, Wikström H.
    J Med Chem; 1993 Oct 29; 36(22):3409-16. PubMed ID: 8230131
    [Abstract] [Full Text] [Related]

  • 19. Effects of WAY 100635 and (-)-5-Me-8-OH-DPAT, a novel 5-HT1A receptor antagonist, on 8-OH-DPAT responses.
    Trillat AC, Malagié I, Mathé-Allainmat M, Anmela MC, Jacquot C, Langlois M, Gardier AM.
    Eur J Pharmacol; 1998 Apr 17; 347(1):41-9. PubMed ID: 9650846
    [Abstract] [Full Text] [Related]

  • 20. 5-hydroxytryptamine (5-HT)1A receptors and the tail-flick response. I. 8-hydroxy-2-(di-n-propylamino) tetralin HBr-induced spontaneous tail-flicks in the rat as an in vivo model of 5-HT1A receptor-mediated activity.
    Millan MJ, Bervoets K, Colpaert FC.
    J Pharmacol Exp Ther; 1991 Mar 17; 256(3):973-82. PubMed ID: 1826033
    [Abstract] [Full Text] [Related]

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