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151 related items for PubMed ID: 8462127

  • 1. Glutathione depletion increases the cytotoxicity of melphalan to PC-3, an androgen-insensitive prostate cancer cell line.
    Canada A, Herman L, Kidd K, Robertson C, Trump D.
    Cancer Chemother Pharmacol; 1993; 32(1):73-7. PubMed ID: 8462127
    [Abstract] [Full Text] [Related]

  • 2. Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione.
    Ozols RF, Louie KG, Plowman J, Behrens BC, Fine RL, Dykes D, Hamilton TC.
    Biochem Pharmacol; 1987 Jan 01; 36(1):147-53. PubMed ID: 3801051
    [Abstract] [Full Text] [Related]

  • 3. Characteristics of the glutathione/glutathione-S-transferase detoxification system in melphalan resistant human prostate cancer cells.
    Ripple M, Mulcahy RT, Wilding G.
    J Urol; 1993 Jul 01; 150(1):209-14. PubMed ID: 8510259
    [Abstract] [Full Text] [Related]

  • 4. Nitrogen mustard-DNA interaction in melphalan-resistant mammary carcinoma cells with elevated intracellular glutathione and glutathione-S-transferase activity.
    Alaoui-Jamali MA, Panasci L, Centurioni GM, Schecter R, Lehnert S, Batist G.
    Cancer Chemother Pharmacol; 1992 Jul 01; 30(5):341-7. PubMed ID: 1505071
    [Abstract] [Full Text] [Related]

  • 5. Role of cellular glutathione and glutathione S-transferase in the expression of alkylating agent cytotoxicity in human breast cancer cells.
    Chen G, Waxman DJ.
    Biochem Pharmacol; 1994 Mar 15; 47(6):1079-87. PubMed ID: 8147907
    [Abstract] [Full Text] [Related]

  • 6. Relationship between melanogenesis, glutathione levels and melphalan toxicity in human melanoma cells.
    Benathan M, Alvero-Jackson H, Mooy AM, Scaletta C, Frenk E.
    Melanoma Res; 1992 Dec 15; 2(5-6):305-14. PubMed ID: 1337997
    [Abstract] [Full Text] [Related]

  • 7. Effect of treatment duration and glutathione depletion on mitomycin C cytotoxicity in vitro.
    Perry RR, Greaves BR, Rasberry U, Barranco SC.
    Cancer Res; 1992 Sep 01; 52(17):4608-12. PubMed ID: 1511428
    [Abstract] [Full Text] [Related]

  • 8. Cytotoxic effects of glutathione synthesis inhibition by L-buthionine-(SR)-sulfoximine on human and murine tumor cells.
    Dorr RT, Liddil JD, Soble MJ.
    Invest New Drugs; 1986 Sep 01; 4(4):305-13. PubMed ID: 3583642
    [Abstract] [Full Text] [Related]

  • 9. Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion.
    Green JA, Vistica DT, Young RC, Hamilton TC, Rogan AM, Ozols RF.
    Cancer Res; 1984 Nov 01; 44(11):5427-31. PubMed ID: 6488194
    [Abstract] [Full Text] [Related]

  • 10. Chemosensitization of L-phenylalanine mustard by the thiol-modulating agent buthionine sulfoximine.
    Kramer RA, Greene K, Ahmad S, Vistica DT.
    Cancer Res; 1987 Mar 15; 47(6):1593-7. PubMed ID: 3815359
    [Abstract] [Full Text] [Related]

  • 11. The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines.
    Mistry P, Kelland LR, Abel G, Sidhar S, Harrap KR.
    Br J Cancer; 1991 Aug 15; 64(2):215-20. PubMed ID: 1892748
    [Abstract] [Full Text] [Related]

  • 12. Effects of glutathione depletion by buthionine sulfoximine on the sensitivity of EMT6/SF cells to chemotherapy agents or X radiation.
    Shrieve DC, Harris JW.
    Int J Radiat Oncol Biol Phys; 1986 Jul 15; 12(7):1171-4. PubMed ID: 3744936
    [Abstract] [Full Text] [Related]

  • 13. Glutathione depletion by L-buthionine sulfoximine antagonizes taxol cytotoxicity.
    Liebmann JE, Hahn SM, Cook JA, Lipschultz C, Mitchell JB, Kaufman DC.
    Cancer Res; 1993 May 01; 53(9):2066-70. PubMed ID: 8097674
    [Abstract] [Full Text] [Related]

  • 14. Synergistic cytotoxicity of buthionine sulfoximine (BSO) and intensive melphalan (L-PAM) for neuroblastoma cell lines established at relapse after myeloablative therapy.
    Anderson CP, Reynolds CP.
    Bone Marrow Transplant; 2002 Aug 01; 30(3):135-40. PubMed ID: 12189530
    [Abstract] [Full Text] [Related]

  • 15. Enhancement of melphalan activity by buthionine sulfoximine and electroporation in melanoma cells.
    Ongaro A, Pellati A, De Mattei M, De Terlizzi F, Rossi CR, Campana LG.
    Anticancer Drugs; 2015 Mar 01; 26(3):284-92. PubMed ID: 25514113
    [Abstract] [Full Text] [Related]

  • 16. Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (L-phenylalanine mustard) in human colorectal cancer cells.
    Vahrmeijer AL, van Dierendonck JH, Schutrups J, van de Velde CJ, Mulder GJ.
    Biochem Pharmacol; 1999 Aug 15; 58(4):655-64. PubMed ID: 10413303
    [Abstract] [Full Text] [Related]

  • 17. Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer.
    O'Dwyer PJ, Hamilton TC, LaCreta FP, Gallo JM, Kilpatrick D, Halbherr T, Brennan J, Bookman MA, Hoffman J, Young RC, Comis RL, Ozols RF.
    J Clin Oncol; 1996 Jan 15; 14(1):249-56. PubMed ID: 8558205
    [Abstract] [Full Text] [Related]

  • 18. In vivo therapeutic potential of combination thiol depletion and alkylating chemotherapy.
    Siemann DW, Beyers KL.
    Br J Cancer; 1993 Dec 15; 68(6):1071-9. PubMed ID: 8260357
    [Abstract] [Full Text] [Related]

  • 19. Changes in glutathione content and resistance to anticancer agents in human stomach cancer cells induced by treatments with melphalan in vitro.
    Barranco SC, Townsend CM, Weintraub B, Beasley EG, MacLean KK, Shaeffer J, Liu NH, Schellenberg K.
    Cancer Res; 1990 Jun 15; 50(12):3614-8. PubMed ID: 2340510
    [Abstract] [Full Text] [Related]

  • 20. Enhanced melphalan cytotoxicity following buthionine sulfoximine-mediated glutathione depletion in a human medulloblastoma xenograft in athymic mice.
    Skapek SX, Colvin OM, Griffith OW, Elion GB, Bigner DD, Friedman HS.
    Cancer Res; 1988 May 15; 48(10):2764-7. PubMed ID: 3359437
    [Abstract] [Full Text] [Related]

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