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Journal Abstract Search


151 related items for PubMed ID: 8462127

  • 21. Effects of glutathione depletion on the cytotoxicity of agents toward a human colonic tumour cell line.
    Jordan J, d'Arcy Doherty M, Cohen GM.
    Br J Cancer; 1987 Jun; 55(6):627-31. PubMed ID: 3620304
    [Abstract] [Full Text] [Related]

  • 22. Sensitivity of human melanoma cells to L-dopa and DL-buthionine (S,R)-sulfoximine.
    Kable EP, Favier D, Parsons PG.
    Cancer Res; 1989 May 01; 49(9):2327-31. PubMed ID: 2706620
    [Abstract] [Full Text] [Related]

  • 23. Time-dependent pharmacodynamic models in cancer chemotherapy: population pharmacodynamic model for glutathione depletion following modulation by buthionine sulfoximine (BSO) in a Phase I trial of melphalan and BSO.
    Gallo JM, Brennan J, Hamilton TC, Halbherr T, Laub PB, Ozols RF, O'Dwyer PJ.
    Cancer Res; 1995 Oct 15; 55(20):4507-11. PubMed ID: 7553617
    [Abstract] [Full Text] [Related]

  • 24. Reduced thiol content in L1210 cells treated with BSO increases DNA crosslinking by melphalan.
    Dorr RT.
    Biochem Biophys Res Commun; 1987 Apr 14; 144(1):47-52. PubMed ID: 3579919
    [Abstract] [Full Text] [Related]

  • 25. Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.
    Russo A, DeGraff W, Friedman N, Mitchell JB.
    Cancer Res; 1986 Jun 14; 46(6):2845-8. PubMed ID: 2421885
    [Abstract] [Full Text] [Related]

  • 26. Effect of D,L-buthionine-S,R-sulfoximine on cytotoxicity and DNA cross-linking induced by bifunctional DNA-reactive cytostatic drugs in human melanoma cells.
    Hansson J, Edgren M, Ehrsson H, Ringborg U, Nilsson B.
    Cancer Res; 1988 Jan 01; 48(1):19-26. PubMed ID: 3334994
    [Abstract] [Full Text] [Related]

  • 27. Mitomycin C sensitivity in human bladder cancer cells: possible role of glutathione and glutathione transferase in resistance.
    Xu BH, Gupta V, Singh SV.
    Arch Biochem Biophys; 1994 Jan 01; 308(1):164-70. PubMed ID: 8311448
    [Abstract] [Full Text] [Related]

  • 28. Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.
    Hamilton TC, Winker MA, Louie KG, Batist G, Behrens BC, Tsuruo T, Grotzinger KR, McKoy WM, Young RC, Ozols RF.
    Biochem Pharmacol; 1985 Jul 15; 34(14):2583-6. PubMed ID: 4040369
    [No Abstract] [Full Text] [Related]

  • 29. Depletion of a discrete nuclear glutathione pool by oxidative stress, but not by buthionine sulfoximine. Correlation with enhanced alkylating agent cytotoxicity to human melanoma cells in vitro.
    Jevtović-Todorović V, Guenthner TM.
    Biochem Pharmacol; 1992 Oct 06; 44(7):1383-93. PubMed ID: 1417960
    [Abstract] [Full Text] [Related]

  • 30. Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
    Ali-Osman F, Antoun G, Wang H, Rajagopal S, Gagucas E.
    Mol Pharmacol; 1996 Jun 06; 49(6):1012-20. PubMed ID: 8649339
    [Abstract] [Full Text] [Related]

  • 31. Potentiation of the cytostatic effect of melphalan on colorectal cancer hepatic metastases by infusion of buthionine sulfoximine (BSO) in the rat: enhanced tumor glutathione depletion by infusion of BSO in the hepatic artery.
    Vahrmeijer AL, van Dierendonck JH, Schutrups J, van de Velde CJ, Mulder GJ.
    Cancer Chemother Pharmacol; 1999 Jun 06; 44(2):111-6. PubMed ID: 10412944
    [Abstract] [Full Text] [Related]

  • 32. Effects of glutathione depletion by buthionine sulfoximine on radiosensitization by oxygen and misonidazole in vitro.
    Shrieve DC, Denekamp J, Minchinton AI.
    Radiat Res; 1985 Jun 06; 102(3):283-94. PubMed ID: 4070545
    [Abstract] [Full Text] [Related]

  • 33. Reversal of melphalan resistance in vivo and in vitro by modulation of glutathione metabolism.
    Medh RD, Gupta V, Awasthi YC.
    Biochem Pharmacol; 1991 Jul 05; 42(2):439-41. PubMed ID: 1859455
    [No Abstract] [Full Text] [Related]

  • 34. Effect of buthionine sulfoximine on PtII and PtIV drug accumulation and the formation of glutathione conjugates in human ovarian-carcinoma cell lines.
    Mistry P, Loh SY, Kelland LR, Harrap KR.
    Int J Cancer; 1993 Nov 11; 55(5):848-56. PubMed ID: 8244583
    [Abstract] [Full Text] [Related]

  • 35. Buthionine sulfoximine and myeloablative concentrations of melphalan overcome resistance in a melphalan-resistant neuroblastoma cell line.
    Anderson CP, Seeger RC, Satake N, Monforte-Munoz HL, Keshelava N, Bailey HH, Reynolds CP.
    J Pediatr Hematol Oncol; 2001 Nov 11; 23(8):500-5. PubMed ID: 11878777
    [Abstract] [Full Text] [Related]

  • 36. Pharmacokinetics of buthionine sulfoximine (NSC 326231) and its effect on melphalan-induced toxicity in mice.
    Smith AC, Liao JT, Page JG, Wientjes MG, Grieshaber CK.
    Cancer Res; 1989 Oct 01; 49(19):5385-91. PubMed ID: 2766304
    [Abstract] [Full Text] [Related]

  • 37. Effects of glutathione depletion on cadmium-induced metallothionein synthesis, cytotoxicity, and proto-oncogene expression in cultured rat myoblasts.
    Shimizu M, Hochadel JF, Waalkes MP.
    J Toxicol Environ Health; 1997 Aug 29; 51(6):609-21. PubMed ID: 9242231
    [Abstract] [Full Text] [Related]

  • 38. Effects of buthionine sulfoximine treatment on cellular glutathione levels and cytotoxicities of cisplatin, carboplatin and radiation in human stomach and ovarian cancer cell lines.
    Lee KS, Kim HK, Moon HS, Hong YS, Kang JH, Kim DJ, Park JG.
    Korean J Intern Med; 1992 Jul 29; 7(2):111-7. PubMed ID: 1306072
    [Abstract] [Full Text] [Related]

  • 39. Buthionine sulphoximine alone and in combination with melphalan (L-PAM) is highly cytotoxic for human neuroblastoma cell lines.
    Anderson CP, Tsai J, Chan W, Park CK, Tian L, Lui RM, Forman HJ, Reynolds CP.
    Eur J Cancer; 1997 Oct 29; 33(12):2016-9. PubMed ID: 9516845
    [Abstract] [Full Text] [Related]

  • 40. Depletion of glutathione after gamma irradiation modifies survival.
    Saunders EL, Meredith MJ, Eisert DR, Freeman ML.
    Radiat Res; 1991 Mar 29; 125(3):267-76. PubMed ID: 2000450
    [Abstract] [Full Text] [Related]


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