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Journal Abstract Search

329 related items for PubMed ID: 8464037

  • 1. Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets.
    Kawasaki AM, Casper MD, Freier SM, Lesnik EA, Zounes MC, Cummins LL, Gonzalez C, Cook PD.
    J Med Chem; 1993 Apr 02; 36(7):831-41. PubMed ID: 8464037
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  • 2. Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression.
    Monia BP, Lesnik EA, Gonzalez C, Lima WF, McGee D, Guinosso CJ, Kawasaki AM, Cook PD, Freier SM.
    J Biol Chem; 1993 Jul 05; 268(19):14514-22. PubMed ID: 8390996
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  • 3. Potent gene-specific inhibitory properties of mixed-backbone antisense oligonucleotides comprised of 2'-deoxy-2'-fluoro-D-arabinose and 2'-deoxyribose nucleotides.
    Lok CN, Viazovkina E, Min KL, Nagy E, Wilds CJ, Damha MJ, Parniak MA.
    Biochemistry; 2002 Mar 12; 41(10):3457-67. PubMed ID: 11876654
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  • 4. Site and mechanism of antisense inhibition by C-5 propyne oligonucleotides.
    Moulds C, Lewis JG, Froehler BC, Grant D, Huang T, Milligan JF, Matteucci MD, Wagner RW.
    Biochemistry; 1995 Apr 18; 34(15):5044-53. PubMed ID: 7536034
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  • 7. Inhibition of translation of hepatitis C virus RNA by 2-modified antisense oligonucleotides.
    Brown-Driver V, Eto T, Lesnik E, Anderson KP, Hanecak RC.
    Antisense Nucleic Acid Drug Dev; 1999 Apr 18; 9(2):145-54. PubMed ID: 10355821
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  • 10. Characterization of antisense oligonucleotides comprising 2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (FANA): specificity, potency, and duration of activity.
    Ferrari N, Bergeron D, Tedeschi AL, Mangos MM, Paquet L, Renzi PM, Damha MJ.
    Ann N Y Acad Sci; 2006 Oct 18; 1082():91-102. PubMed ID: 17145930
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  • 11. Phosphorothioate-phosphodiester oligonucleotide co-polymers: assessment for antisense application.
    Ghosh MK, Ghosh K, Cohen JS.
    Anticancer Drug Des; 1993 Feb 18; 8(1):15-32. PubMed ID: 8386513
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  • 12. Synthesis of chimeric oligonucleotides containing phosphodiester, phosphorothioate, and phosphoramidate linkages.
    Maier MA, Guzaev AP, Manoharan M.
    Org Lett; 2000 Jun 29; 2(13):1819-22. PubMed ID: 10891166
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  • 13. Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-alpha by the incorporation of 2'-O-propyl modifications.
    McKay RA, Cummins LL, Graham MJ, Lesnik EA, Owens SR, Winniman M, Dean NM.
    Nucleic Acids Res; 1996 Feb 01; 24(3):411-7. PubMed ID: 8602351
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  • 14. Synthetic oligonucleotides for biomedical applications.
    Seliger H, Fröhlich A, Gröger G, Krist B, Montenarh M, Rösch H, Rösch R, Ortigao FR.
    Nucleic Acids Symp Ser; 1991 Feb 01; (24):193-6. PubMed ID: 1726743
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  • 15. Phosphorothioate oligonucleotides block reverse transcription by the Rnase H activity associated with the HIV-1 polymerase.
    Hatta T, Takai K, Yokoyama S, Nakashima H, Yamamoto N, Takaku H.
    Biochem Biophys Res Commun; 1995 Jun 26; 211(3):1041-6. PubMed ID: 7541196
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  • 17. Chimeric oligodeoxynucleotide analogues: enhanced cell uptake of structures which direct ribonuclease H with high specificity.
    Giles RV, Spiller DG, Tidd DM.
    Anticancer Drug Des; 1993 Feb 26; 8(1):33-51. PubMed ID: 8386514
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  • 18. RNase H cleavage of RNA hybridized to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bonds.
    Furdon PJ, Dominski Z, Kole R.
    Nucleic Acids Res; 1989 Nov 25; 17(22):9193-204. PubMed ID: 2555787
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  • 19. Antisense oligonuclotides with oxetane-constrained cytidine enhance heteroduplex stability, and elicit satisfactory RNase H response as well as showing improved resistance to both exo and endonucleases.
    Pradeepkumar PI, Amirkhanov NV, Chattopadhyaya J.
    Org Biomol Chem; 2003 Jan 07; 1(1):81-92. PubMed ID: 12929393
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  • 20. Fine tuning of electrostatics around the internucleotidic phosphate through incorporation of modified 2',4'-carbocyclic-LNAs and -ENAs leads to significant modulation of antisense properties.
    Zhou C, Liu Y, Andaloussi M, Badgujar N, Plashkevych O, Chattopadhyaya J.
    J Org Chem; 2009 Jan 02; 74(1):118-34. PubMed ID: 19055352
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