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150 related items for PubMed ID: 8464042

  • 1. Adenosine-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase.
    Liu S, Wnuk SF, Yuan C, Robins MJ, Borchardt RT.
    J Med Chem; 1993 Apr 02; 36(7):883-7. PubMed ID: 8464042
    [Abstract] [Full Text] [Related]

  • 2. Aristeromycin-5'-carboxaldehyde: a potent inhibitor of S-adenosyl-L-homocysteine hydrolase.
    Liu S, Yuan CS, Borchardt RT.
    J Med Chem; 1996 Jun 07; 39(12):2347-53. PubMed ID: 8691429
    [Abstract] [Full Text] [Related]

  • 3. The mechanism of inactivation of human placental S-adenosylhomocysteine hydrolase by (E)-4',5'-didehydro-5'-methoxyadenosine and adenosine 5'-carboxaldehyde oxime.
    Huang H, Yuan CS, Wnuk SF, Robins MJ, Borchardt RT.
    Arch Biochem Biophys; 1997 Jul 01; 343(1):109-17. PubMed ID: 9210652
    [Abstract] [Full Text] [Related]

  • 4. Nucleic acid related compounds. 84. Synthesis of 6'-(E and Z)-halohomovinyl derivatives of adenosine, inactivation of S-adenosyl-L-homocysteine hydrolase, and correlation of anticancer and antiviral potencies with enzyme inhibition.
    Wnuk SF, Yuan CS, Borchardt RT, Balzarini J, De Clercq E, Robins MJ.
    J Med Chem; 1994 Oct 14; 37(21):3579-87. PubMed ID: 7932585
    [Abstract] [Full Text] [Related]

  • 5. Inactivation of S-adenosyl-L-homocysteine hydrolase with fluorinated analogs of 2'- and 3'-deoxy-5'-methylthioadenosine.
    Guillerm D, Guillerm G, Witkowski-Vandenplas C.
    Nucleosides Nucleotides Nucleic Acids; 2001 Oct 14; 20(4-7):689-93. PubMed ID: 11563093
    [Abstract] [Full Text] [Related]

  • 6. (E)-5',6'-didehydro-6'-deoxy-6'-fluorohomoadenosine: a substrate that measures the hydrolytic activity of S-adenosylhomocysteine hydrolase.
    Yuan CS, Wnuk SF, Liu S, Robins MJ, Borchardt RT.
    Biochemistry; 1994 Oct 11; 33(40):12305-11. PubMed ID: 7918452
    [Abstract] [Full Text] [Related]

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  • 8. Mechanism of inactivation of S-adenosyl-L-homocysteine hydrolase by 5'-deoxy-5'-S-allenylthioadenosine and 5'-deoxy-5'-S-propynylthioadenosine.
    Guillerm G, Guillerm D, Witkowski-Vandenplas C.
    Nucleosides Nucleotides Nucleic Acids; 2001 Oct 11; 20(4-7):685-8. PubMed ID: 11563092
    [Abstract] [Full Text] [Related]

  • 9. Targeting "hydrolytic" activity of the S-adenosyl-L-homocysteine hydrolase.
    Wnuk SF.
    Mini Rev Med Chem; 2001 Sep 11; 1(3):307-16. PubMed ID: 12369977
    [Abstract] [Full Text] [Related]

  • 10. The mechanism of inhibition of S-adenosyl-L-homocysteine hydrolase by fluorine-containing adenosine analogs.
    Mehdi S, Jarvi ET, Koehl JR, McCarthy JR, Bey P.
    J Enzyme Inhib; 1990 Sep 11; 4(1):1-13. PubMed ID: 2094766
    [Abstract] [Full Text] [Related]

  • 11. Anticancer and antiviral effects and inactivation of S-adenosyl-L-homocysteine hydrolase with 5'-carboxaldehydes and oximes synthesized from adenosine and sugar-modified analogues.
    Wnuk SF, Yuan CS, Borchardt RT, Balzarini J, De Clercq E, Robins MJ.
    J Med Chem; 1997 May 23; 40(11):1608-18. PubMed ID: 9171871
    [Abstract] [Full Text] [Related]

  • 12. Mechanism of inactivation of S-adenosylhomocysteine hydrolase by (Z)-4',5'-didehydro-5'-deoxy-5'-fluoroadenosine.
    Yuan CS, Yeh J, Liu S, Borchardt RT.
    J Biol Chem; 1993 Aug 15; 268(23):17030-7. PubMed ID: 8349591
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of an alpha-aminophosphonate nucleoside as an inhibitor of S-adenosyl-L-homocysteine hydrolase.
    Steere JA, Sampson PB, Honek JF.
    Bioorg Med Chem Lett; 2002 Feb 11; 12(3):457-60. PubMed ID: 11814819
    [Abstract] [Full Text] [Related]

  • 14. The mechanism of inactivation of S-adenosylhomocysteine hydrolase by fluorinated analogs of 5'-methylthioadenosine.
    Muzard M, Vandenplas C, Guillerm D, Guillerm G.
    J Enzyme Inhib; 1998 Sep 11; 13(6):443-56. PubMed ID: 9825307
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of homologated halovinyl derivatives from aristeromycin and their inhibition of human placental S-adenosyl-L-homocysteine hydrolase.
    Wnuk SF, Yuan CS, Borchardt RT, Robins MJ.
    Nucleosides Nucleotides; 1998 Sep 11; 17(1-3):99-113. PubMed ID: 9708344
    [Abstract] [Full Text] [Related]

  • 16. Effects of 4'-modified analogs of aristeromycin on the metabolism of S-adenosyl-L-homocysteine in murine L929 cells.
    Ault-Riché DB, Lee Y, Yuan CS, Hasobe M, Wolfe MS, Borcherding DR, Borchardt RT.
    Mol Pharmacol; 1993 Jun 11; 43(6):989-97. PubMed ID: 8316227
    [Abstract] [Full Text] [Related]

  • 17. 4',5'-unsaturated 5'-halogenated nucleosides. Mechanism-based and competitive inhibitors of S-adenosyl-L-homocysteine hydrolase.
    Jarvi ET, McCarthy JR, Mehdi S, Matthews DP, Edwards ML, Prakash NJ, Bowlin TL, Sunkara PS, Bey P.
    J Med Chem; 1991 Feb 11; 34(2):647-56. PubMed ID: 1995889
    [Abstract] [Full Text] [Related]

  • 18. Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosine analogues (4'-haloacetylene analogues derived from adenosine).
    Robins MJ, Wnuk SF, Yang X, Yuan CS, Borchardt RT, Balzarini J, De Clercq E.
    J Med Chem; 1998 Sep 24; 41(20):3857-64. PubMed ID: 9748360
    [Abstract] [Full Text] [Related]

  • 19. New neplanocin analogues. 12. Alternative synthesis and antimalarial effect of (6'R)-6'-C-methylneplanocin A, a potent AdoHcy hydrolase inhibitor.
    Shuto S, Minakawa N, Niizuma S, Kim HS, Wataya Y, Matsuda A.
    J Med Chem; 2002 Jan 31; 45(3):748-51. PubMed ID: 11806727
    [Abstract] [Full Text] [Related]

  • 20. Synthesis of S-adenosyl-L-homocysteine hydrolase inhibitors and their biological activities.
    Kitade Y, Kozaki A, Gotoh T, Miwa T, Nakanishi M, Yatome C.
    Nucleic Acids Symp Ser; 1999 Jan 31; (42):25-6. PubMed ID: 10780361
    [Abstract] [Full Text] [Related]

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