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Journal Abstract Search

77 related items for PubMed ID: 8464076

  • 1. Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductase.
    Stammers DK, Delves C, Ballantine S, Jones EY, Stuart DI, Achari A, Bryant PK, Champness JN.
    J Mol Biol; 1993 Mar 20; 230(2):679-80. PubMed ID: 8464076
    [Abstract] [Full Text] [Related]

  • 2. Refolding of recombinant Pneumocystis carinii dihydrofolate reductase and characterization of the enzyme.
    Delves CJ, Ballantine SP, Tansik RL, Baccanari DP, Stammers DK.
    Protein Expr Purif; 1993 Feb 20; 4(1):16-23. PubMed ID: 8425104
    [Abstract] [Full Text] [Related]

  • 3. Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+.
    Cody V, Galitsky N, Rak D, Luft JR, Pangborn W, Queener SF.
    Biochemistry; 1999 Apr 06; 38(14):4303-12. PubMed ID: 10194348
    [Abstract] [Full Text] [Related]

  • 4. New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions.
    Cody V, Pace J, Chisum K, Rosowsky A.
    Proteins; 2006 Dec 01; 65(4):959-69. PubMed ID: 17019704
    [Abstract] [Full Text] [Related]

  • 5. Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase.
    Cody V, Galitsky N, Luft JR, Pangborn W, Queener SF, Gangjee A.
    Acta Crystallogr D Biol Crystallogr; 2002 Sep 01; 58(Pt 9):1393-9. PubMed ID: 12198294
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  • 7. Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry.
    Cody V, Luft JR, Pangborn W, Gangjee A, Queener SF.
    Acta Crystallogr D Biol Crystallogr; 2004 Apr 01; 60(Pt 4):646-55. PubMed ID: 15039552
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  • 9. Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523.
    Cody V, Galitsky N, Luft JR, Pangborn W, Rosowsky A, Blakley RL.
    Biochemistry; 1997 Nov 11; 36(45):13897-903. PubMed ID: 9374868
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  • 10. Inhibitory properties and X-ray crystallographic study of the binding of AR-101, AR-102 and iclaprim in ternary complexes with NADPH and dihydrofolate reductase from Staphylococcus aureus.
    Oefner C, Parisi S, Schulz H, Lociuro S, Dale GE.
    Acta Crystallogr D Biol Crystallogr; 2009 Aug 11; 65(Pt 8):751-7. PubMed ID: 19622858
    [Abstract] [Full Text] [Related]

  • 11. The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution.
    Champness JN, Achari A, Ballantine SP, Bryant PK, Delves CJ, Stammers DK.
    Structure; 1994 Oct 15; 2(10):915-24. PubMed ID: 7866743
    [Abstract] [Full Text] [Related]

  • 12. Calorimetric studies of ligand binding in R67 dihydrofolate reductase.
    Jackson M, Chopra S, Smiley RD, Maynord PO, Rosowsky A, London RE, Levy L, Kalman TI, Howell EE.
    Biochemistry; 2005 Sep 20; 44(37):12420-33. PubMed ID: 16156655
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  • 13. Unusual binding stoichiometries and cooperativity are observed during binary and ternary complex formation in the single active pore of R67 dihydrofolate reductase, a D2 symmetric protein.
    Bradrick TD, Beechem JM, Howell EE.
    Biochemistry; 1996 Sep 03; 35(35):11414-24. PubMed ID: 8784197
    [Abstract] [Full Text] [Related]

  • 14. Thermal denaturation of bacterial and bovine dihydrofolate reductases and their complexes with NADPH, trimethoprim and methotrexate.
    Sasso S, Protasevich I, Gilli R, Makarov A, Briand C.
    J Biomol Struct Dyn; 1995 Apr 03; 12(5):1023-32. PubMed ID: 7626237
    [Abstract] [Full Text] [Related]

  • 15. Characterization, crystallization and preliminary X-ray analysis of bifunctional dihydrofolate reductase-thymidylate synthase from Plasmodium falciparum.
    Chitnumsub P, Yuvaniyama J, Vanichtanankul J, Kamchonwongpaisan S, Walkinshaw MD, Yuthavong Y.
    Acta Crystallogr D Biol Crystallogr; 2004 Apr 03; 60(Pt 4):780-3. PubMed ID: 15039585
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  • 17. Structural comparison of chromosomal and exogenous dihydrofolate reductase from Staphylococcus aureus in complex with the potent inhibitor trimethoprim.
    Heaslet H, Harris M, Fahnoe K, Sarver R, Putz H, Chang J, Subramanyam C, Barreiro G, Miller JR.
    Proteins; 2009 Aug 15; 76(3):706-17. PubMed ID: 19280600
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  • 18. Crystallization and preliminary crystallographic studies of the D59A mutant of MicA, a YycF response-regulator homologue from Streptococcus pneumoniae.
    Riboldi-Tunnicliffe A, Trombe MC, Bent CJ, Isaacs NW, Mitchell TJ.
    Acta Crystallogr D Biol Crystallogr; 2004 May 15; 60(Pt 5):950-1. PubMed ID: 15103149
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  • 19. Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs.
    Li R, Sirawaraporn R, Chitnumsub P, Sirawaraporn W, Wooden J, Athappilly F, Turley S, Hol WG.
    J Mol Biol; 2000 Jan 14; 295(2):307-23. PubMed ID: 10623528
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