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Journal Abstract Search
77 related items for PubMed ID: 8464076
41. Protein-drug interactions: characterization of inhibitor binding in complexes of DHFR with trimethoprim and related derivatives. Fleischman SH, Brooks CL. Proteins; 1990; 7(1):52-61. PubMed ID: 2330368 [Abstract] [Full Text] [Related]
42. Overexpression, crystallization and preliminary X-ray crystallographic analysis of dihydrofolate reductase from bacteriophage T4. Oh YK, Moon J, Lee JY, Cho SW, Shin W, Suh SW. Acta Crystallogr D Biol Crystallogr; 2000 Jun; 56(Pt 6):775-7. PubMed ID: 10818362 [Abstract] [Full Text] [Related]
43. The structure of mouse L1210 dihydrofolate reductase-drug complexes and the construction of a model of human enzyme. Stammers DK, Champness JN, Beddell CR, Dann JG, Eliopoulos E, Geddes AJ, Ogg D, North AC. FEBS Lett; 1987 Jun 22; 218(1):178-84. PubMed ID: 3595861 [Abstract] [Full Text] [Related]
44. Purification, crystallization and preliminary X-ray analysis of L-sorbose reductase from Gluconobacter frateurii complexed with L-sorbose or NADPH. Kubota K, Nagata K, Miyazono K, Toyama H, Matsushita K, Tanokura M. Acta Crystallogr Sect F Struct Biol Cryst Commun; 2009 Jun 01; 65(Pt 6):562-4. PubMed ID: 19478431 [Abstract] [Full Text] [Related]
46. Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase. Cody V, Pace J, Piraino J, Queener SF. J Struct Biol; 2011 Oct 01; 176(1):52-9. PubMed ID: 21684339 [Abstract] [Full Text] [Related]
49. Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Bourne CR, Bunce RA, Bourne PC, Berlin KD, Barrow EW, Barrow WW. Antimicrob Agents Chemother; 2009 Jul 01; 53(7):3065-73. PubMed ID: 19364848 [Abstract] [Full Text] [Related]
50. Structural analysis of Pneumocystis carinii dihydrofolate reductase complexed with NADPH and 2,4-diamino-6-[2-(5-carboxypent-1-yn-1-yl)-5-methoxybenzyl]-5-methylpyrido[2,3-d]pyrimidine. Cody V, Pace J, Stewart E. Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Apr 01; 68(Pt 4):418-23. PubMed ID: 22505410 [Abstract] [Full Text] [Related]
51. 1H and 31P NMR characterization of two conformations of the trimethoprim-NADP+-dihydrofolate reductase complex. Gronenborn A, Birdsall B, Hyde E, Roberts G, Feeney J, Burgen A. Mol Pharmacol; 1981 Jul 01; 20(1):145-53. PubMed ID: 6793843 [No Abstract] [Full Text] [Related]
56. The effect of codon 31 on the relative affinities for the binding of designed 8-alkyl-pterins to dihydrofolate reductase: a statistical perturbation theory and molecular dynamics simulation study. Cummins PL, Gready JE. Adv Exp Med Biol; 1993 Jul 01; 338():511-4. PubMed ID: 8304169 [No Abstract] [Full Text] [Related]
59. Preliminary crystallographic data for NAD(P)H quinone reductase isolated from the Walker 256 rat carcinoma cell line. Skelly JV, Suter DA, Knox RJ, Garman E, Stuart DI, Sanderson MR, Roberts JJ, Neidle S. J Mol Biol; 1989 Feb 05; 205(3):623-4. PubMed ID: 2494346 [Abstract] [Full Text] [Related]