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Journal Abstract Search


168 related items for PubMed ID: 8466542

  • 1. Hepatic and intrahepatic targeting of an anti-inflammatory agent with human serum albumin and neoglycoproteins as carrier molecules.
    Franssen EJ, Jansen RW, Vaalburg M, Meijer DK.
    Biochem Pharmacol; 1993 Mar 24; 45(6):1215-26. PubMed ID: 8466542
    [Abstract] [Full Text] [Related]

  • 2. Targeting of naproxen covalently linked to HSA to sinusoidal cell types of the liver.
    Melgert BN, Wartna E, Lebbe C, Albrecht C, Molema G, Poelstra K, Reichen J, Meijer DK.
    J Drug Target; 1998 Mar 24; 5(5):329-42. PubMed ID: 9771615
    [Abstract] [Full Text] [Related]

  • 3. Effect of chronic bile duct obstruction and LPS upon targeting of naproxen to the liver using naproxen-albumin conjugate.
    Albrecht C, Melgert BN, Reichen J, Poelstra K, Meijer DK.
    J Drug Target; 1998 Mar 24; 6(2):105-17. PubMed ID: 9886235
    [Abstract] [Full Text] [Related]

  • 4. Targeting naproxen coupled to human serum albumin to nonparenchymal cells reduces endotoxin-induced mortality in rats with biliary cirrhosis.
    Albrecht C, Meijer DK, Lebbe C, Sägesser H, Melgert BN, Poelstra K, Reichen J.
    Hepatology; 1997 Dec 24; 26(6):1553-9. PubMed ID: 9397997
    [Abstract] [Full Text] [Related]

  • 5. Hepatic endocytosis of various types of mannose-terminated albumins. What is important, sugar recognition, net charge, or the combination of these features.
    Jansen RW, Molema G, Ching TL, Oosting R, Harms G, Moolenaar F, Hardonk MJ, Meijer DK.
    J Biol Chem; 1991 Feb 15; 266(5):3343-8. PubMed ID: 1993707
    [Abstract] [Full Text] [Related]

  • 6. Coupling of the antiviral drug ara-AMP to lactosaminated albumin leads to specific uptake in rat and human hepatocytes.
    Jansen RW, Kruijt JK, van Berkel TJ, Meijer DK.
    Hepatology; 1993 Jul 15; 18(1):146-52. PubMed ID: 7686877
    [Abstract] [Full Text] [Related]

  • 7. Low molecular weight proteins as carriers for renal drug targeting: naproxen coupled to lysozyme via the spacer L-lactic acid.
    Franssen EJ, Moolenaar F, de Zeeuw D, Meijer DK.
    Pharm Res; 1993 Jul 15; 10(7):963-9. PubMed ID: 8378258
    [Abstract] [Full Text] [Related]

  • 8. Drug targeting to the liver with lactosylated albumins: does the glycoprotein target the drug or is the drug targeting the glycoprotein?
    van der Sluijs P, Bootsma HP, Postema B, Moolenaar F, Meijer DK.
    Hepatology; 1986 Jul 15; 6(4):723-8. PubMed ID: 3089897
    [Abstract] [Full Text] [Related]

  • 9. Targeting of sugar- and charge-modified albumins to fibrotic rat livers: the accessibility of hepatic cells after chronic bile duct ligation.
    Beljaars L, Poelstra K, Molema G, Meijer DK.
    J Hepatol; 1998 Oct 15; 29(4):579-88. PubMed ID: 9824267
    [Abstract] [Full Text] [Related]

  • 10. Low molecular weight proteins as carriers for renal drug targeting: naproxen-lysozyme.
    Franssen EJ, van Amsterdam RG, Visser J, Moolenaar F, de Zeeuw D, Meijer DK.
    Pharm Res; 1991 Oct 15; 8(10):1223-30. PubMed ID: 1796038
    [Abstract] [Full Text] [Related]

  • 11. Pharmacokinetic analysis and cellular distribution of the anti-HIV compound succinylated human serum albumin (Suc-HSA) in vivo and in the isolated perfused rat liver.
    Jansen RW, Olinga P, Harms G, Meijer DK.
    Pharm Res; 1993 Nov 15; 10(11):1611-4. PubMed ID: 8290473
    [Abstract] [Full Text] [Related]

  • 12. Targeting dexamethasone to Kupffer cells: effects on liver inflammation and fibrosis in rats.
    Melgert BN, Olinga P, Van Der Laan JM, Weert B, Cho J, Schuppan D, Groothuis GM, Meijer DK, Poelstra K.
    Hepatology; 2001 Oct 15; 34(4 Pt 1):719-28. PubMed ID: 11584368
    [Abstract] [Full Text] [Related]

  • 13. Comparative pharmacokinetic, immunologic and hematologic studies on the anti-HIV-1/2 compounds aconitylated and succinylated HSA.
    Swart PJ, Beljaars E, Smit C, Pasma A, Schuitemaker H, Meijer DK.
    J Drug Target; 1996 Oct 15; 4(2):109-16. PubMed ID: 8894971
    [Abstract] [Full Text] [Related]

  • 14. Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells.
    Kamps JA, Morselt HW, Swart PJ, Meijer DK, Scherphof GL.
    Proc Natl Acad Sci U S A; 1997 Oct 14; 94(21):11681-5. PubMed ID: 9326670
    [Abstract] [Full Text] [Related]

  • 15. Differentiation between naproxen, naproxen-protein conjugates, and naproxen-lysine in plasma via micellar electrokinetic capillary chromatography--a new approach in the bioanalysis of drug targeting preparations.
    Albrecht C, Reichen J, Visser J, Meijer DK, Thormann W.
    Clin Chem; 1997 Nov 14; 43(11):2083-90. PubMed ID: 9365392
    [Abstract] [Full Text] [Related]

  • 16. Synthesis of a targeting drug for antifibrosis of liver; a conjugate for delivering glycyrrhetin to hepatic stellate cells.
    Zhang J, Zhang QS, Chen XM, Tian GY.
    Glycoconj J; 2002 Jul 14; 19(6):423-9. PubMed ID: 14707489
    [Abstract] [Full Text] [Related]

  • 17. Disease-induced drug targeting using novel peptide-ligand albumins.
    Meijer DK, Beljaars L, Molema G, Poelstra K.
    J Control Release; 2001 May 14; 72(1-3):157-64. PubMed ID: 11389994
    [Abstract] [Full Text] [Related]

  • 18. Albumin modified with mannose 6-phosphate: A potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells.
    Beljaars L, Molema G, Weert B, Bonnema H, Olinga P, Groothuis GM, Meijer DK, Poelstra K.
    Hepatology; 1999 May 14; 29(5):1486-93. PubMed ID: 10216133
    [Abstract] [Full Text] [Related]

  • 19. Dexamethasone coupled to albumin is selectively taken up by rat nonparenchymal liver cells and attenuates LPS-induced activation of hepatic cells.
    Melgert BN, Olinga P, Jack VK, Molema G, Meijer DK, Poelstra K.
    J Hepatol; 2000 Apr 14; 32(4):603-11. PubMed ID: 10782909
    [Abstract] [Full Text] [Related]

  • 20. Stereoselective binding properties of naproxen glucuronide diastereomers to proteins.
    Bischer A, Zia-Amirhosseini P, Iwaki M, McDonagh AF, Benet LZ.
    J Pharmacokinet Biopharm; 1995 Aug 14; 23(4):379-95. PubMed ID: 8882746
    [Abstract] [Full Text] [Related]


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