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Journal Abstract Search

174 related items for PubMed ID: 8471072

  • 1. Differential effects of active isomers, segments, and analogs of dolastatin 10 on ligand interactions with tubulin. Correlation with cytotoxicity.
    Bai R, Roach MC, Jayaram SK, Barkoczy J, Pettit GR, Ludueña RF, Hamel E.
    Biochem Pharmacol; 1993 Apr 06; 45(7):1503-15. PubMed ID: 8471072
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  • 2. Structure-activity studies with chiral isomers and with segments of the antimitotic marine peptide dolastatin 10.
    Bai RL, Pettit GR, Hamel E.
    Biochem Pharmacol; 1990 Oct 15; 40(8):1859-64. PubMed ID: 2242019
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  • 3. Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain.
    Bai R, Pettit GR, Hamel E.
    Biochem Pharmacol; 1990 Jun 15; 39(12):1941-9. PubMed ID: 2353935
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  • 8. Inhibition of tubulin polymerization by vitilevuamide, a bicyclic marine peptide, at a site distinct from colchicine, the vinca alkaloids, and dolastatin 10.
    Edler MC, Fernandez AM, Lassota P, Ireland CM, Barrows LR.
    Biochem Pharmacol; 2002 Feb 15; 63(4):707-15. PubMed ID: 11992639
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  • 9. Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites.
    Bai RL, Pettit GR, Hamel E.
    J Biol Chem; 1990 Oct 05; 265(28):17141-9. PubMed ID: 2211617
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  • 10. Direct photoaffinity labeling by dolastatin 10 of the amino-terminal peptide of beta-tubulin containing cysteine 12.
    Bai R, Covell DG, Taylor GF, Kepler JA, Copeland TD, Nguyen NY, Pettit GR, Hamel E.
    J Biol Chem; 2004 Jul 16; 279(29):30731-40. PubMed ID: 15123603
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  • 12. Interaction of marine toxin dolastatin 10 with porcine brain tubulin: competitive inhibition of rhizoxin and phomopsin A binding.
    Li Y, Kobayashi H, Hashimoto Y, Shirai R, Hirata A, Hayashi K, Hamada Y, Shioiri T, Iwasaki S.
    Chem Biol Interact; 1994 Dec 16; 93(3):175-83. PubMed ID: 7923438
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  • 13. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
    Bai R, Cichacz ZA, Herald CL, Pettit GR, Hamel E.
    Mol Pharmacol; 1993 Oct 16; 44(4):757-66. PubMed ID: 8232226
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  • 14. Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin.
    Cruz-Monserrate Z, Vervoort HC, Bai R, Newman DJ, Howell SB, Los G, Mullaney JT, Williams MD, Pettit GR, Fenical W, Hamel E.
    Mol Pharmacol; 2003 Jun 16; 63(6):1273-80. PubMed ID: 12761336
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  • 15. Antineoplastic agents 337. Synthesis of dolastatin 10 structural modifications.
    Pettit GR, Srirangam JK, Barkoczy J, Williams MD, Durkin KP, Boyd MR, Bai R, Hamel E, Schmidt JM, Chapuis JC.
    Anticancer Drug Des; 1995 Oct 16; 10(7):529-44. PubMed ID: 7495477
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  • 16. Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data.
    Bai RL, Paull KD, Herald CL, Malspeis L, Pettit GR, Hamel E.
    J Biol Chem; 1991 Aug 25; 266(24):15882-9. PubMed ID: 1874739
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  • 17. Characterization of the interaction of TZT-1027, a potent antitumor agent, with tubulin.
    Natsume T, Watanabe J, Tamaoki S, Fujio N, Miyasaka K, Kobayashi M.
    Jpn J Cancer Res; 2000 Jul 25; 91(7):737-47. PubMed ID: 10920282
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  • 18. Interaction of ustiloxin A with bovine brain tubulin.
    Ludueńa RF, Roach MC, Prasad V, Banerjee M, Koiso Y, Li Y, Iwasaki S.
    Biochem Pharmacol; 1994 Apr 29; 47(9):1593-9. PubMed ID: 8185673
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  • 19. Antineoplastic agents 365. Dolastatin 10 SAR probes.
    Pettit GR, Srirangam JK, Barkoczy J, Williams MD, Boyd MR, Hamel E, Pettit RK, Hogan F, Bai R, Chapuis JC, McAllister SC, Schmidt JM.
    Anticancer Drug Des; 1998 Jun 29; 13(4):243-77. PubMed ID: 9627667
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  • 20. In vitro activities and postantifungal effects of the potent dolastatin 10 derivative auristatin PHE.
    Woyke T, Pettit GR, Winkelmann G, Pettit RK.
    Antimicrob Agents Chemother; 2001 Dec 29; 45(12):3580-4. PubMed ID: 11709343
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