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280 related items for PubMed ID: 8474431

  • 1. Regulation of thymidylate synthase in human colon cancer cells treated with 5-fluorouracil and interferon-gamma.
    Chu E, Koeller DM, Johnston PG, Zinn S, Allegra CJ.
    Mol Pharmacol; 1993 Apr; 43(4):527-33. PubMed ID: 8474431
    [Abstract] [Full Text] [Related]

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  • 3. Induction of thymidylate synthase associated with multidrug resistance in human breast and colon cancer cell lines.
    Chu E, Drake JC, Koeller DM, Zinn S, Jamis-Dow CA, Yeh GC, Allegra CJ.
    Mol Pharmacol; 1991 Feb; 39(2):136-43. PubMed ID: 1704999
    [Abstract] [Full Text] [Related]

  • 4. Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines.
    Johnston PG, Drake JC, Trepel J, Allegra CJ.
    Cancer Res; 1992 Aug 15; 52(16):4306-12. PubMed ID: 1643628
    [Abstract] [Full Text] [Related]

  • 5. Cell cycle regulation of the G0/G1 transition in 5-fluorouracil-sensitive and -resistant human colon cancer cell lines.
    McGinn CJ, Pestalozzi BC, Drake JC, Glennon MC, Kunugi K, Otterson G, Allegra CJ, Johnston PG, Kinsella TJ.
    Cancer J; 2000 Aug 15; 6(4):234-42. PubMed ID: 11038143
    [Abstract] [Full Text] [Related]

  • 6. The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates.
    Longley DB, Boyer J, Allen WL, Latif T, Ferguson PR, Maxwell PJ, McDermott U, Lynch M, Harkin DP, Johnston PG.
    Cancer Res; 2002 May 01; 62(9):2644-9. PubMed ID: 11980662
    [Abstract] [Full Text] [Related]

  • 7. Regulation of p53 expression in response to 5-fluorouracil in human cancer RKO cells.
    Ju J, Schmitz JC, Song B, Kudo K, Chu E.
    Clin Cancer Res; 2007 Jul 15; 13(14):4245-51. PubMed ID: 17634554
    [Abstract] [Full Text] [Related]

  • 8. Chronic exposure of colorectal cancer cells in culture to fluoropyrimidine analogs induces thymidylate synthase and suppresses p53. A molecular explanation for the mechanism of 5-FU resistance.
    Subbarayan PR, Sarkar M, Nelson G, Benitez E, Singhal S, Ardalan B.
    Anticancer Res; 2010 Apr 15; 30(4):1149-56. PubMed ID: 20530421
    [Abstract] [Full Text] [Related]

  • 9. Detection and quantitation of thymidylate synthase mRNA in human colon adenocarcinoma cell line resistant to 5-fluorouracil by competitive PCR.
    Shibata J, Aiba K, Shibata H, Minowa S, Horikoshi N.
    Anticancer Res; 1998 Apr 15; 18(3A):1457-63. PubMed ID: 9673356
    [Abstract] [Full Text] [Related]

  • 10. Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer.
    Xi Y, Nakajima G, Schmitz JC, Chu E, Ju J.
    BMC Genomics; 2006 Apr 03; 7():68. PubMed ID: 16584549
    [Abstract] [Full Text] [Related]

  • 11. Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil.
    Copur S, Aiba K, Drake JC, Allegra CJ, Chu E.
    Biochem Pharmacol; 1995 May 17; 49(10):1419-26. PubMed ID: 7763285
    [Abstract] [Full Text] [Related]

  • 12. Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
    Nita ME, Tominaga O, Nagawa H, Tsuruo T, Muto T.
    Hepatogastroenterology; 1998 May 17; 45(24):2117-22. PubMed ID: 9951876
    [Abstract] [Full Text] [Related]

  • 13. Enhancement of 5-fluorouracil sensitivity by an rTS signaling mimic in H630 colon cancer cells.
    Dolnick R, Wu Q, Angelino NJ, Stephanie LV, Chow KC, Sufrin JR, Dolnick BJ.
    Cancer Res; 2005 Jul 01; 65(13):5917-24. PubMed ID: 15994970
    [Abstract] [Full Text] [Related]

  • 14. Differential regulation of carcinoembryonic antigen and biliary glycoprotein by gamma-interferon.
    Takahashi H, Okai Y, Paxton RJ, Hefta LJ, Shively JE.
    Cancer Res; 1993 Apr 01; 53(7):1612-9. PubMed ID: 8453631
    [Abstract] [Full Text] [Related]

  • 15. Determinants of cytotoxicity with prolonged exposure to fluorouracil in human colon cancer cells.
    Ren Q, Van Groeningen CJ, Hardcastle A, Aherne GW, Geoffroy F, Allegra CJ, Johnston PG, Grem JL.
    Oncol Res; 1997 Apr 01; 9(2):77-88. PubMed ID: 9167189
    [Abstract] [Full Text] [Related]

  • 16. Interferon beta increases antitumor activity of 5-fluorouracil against human colon carcinoma cells in vitro and in vivo.
    Kase S, Kubota T, Watanabe M, Furukawa T, Tanino H, Ishibiki K, Teramoto T, Kitajima M.
    Anticancer Res; 1993 Apr 01; 13(2):369-73. PubMed ID: 8517649
    [Abstract] [Full Text] [Related]

  • 17. The transfection of thymidylate synthase antisense suppresses oncogenic properties of a human colon cancer cell line and augments the antitumor effect of fluorouracil.
    Matsuoka K, Tsukuda K, Suda M, Kobayashi K, Ota T, Okita A, Watanabe K, Suzuki E, Murakami M, Doihara H, Shimizu N.
    Int J Oncol; 2004 Jan 01; 24(1):217-22. PubMed ID: 14654960
    [Abstract] [Full Text] [Related]

  • 18. Prolonged and enhanced suppression of thymidylate synthase by weekly 24-h infusion of high-dose 5-fluorouracil.
    Yeh KH, Yeh SH, Hsu CH, Wang TM, Ma IF, Cheng AL.
    Br J Cancer; 2000 Dec 01; 83(11):1510-5. PubMed ID: 11076661
    [Abstract] [Full Text] [Related]

  • 19. Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors.
    Wang W, Marsh S, Cassidy J, McLeod HL.
    Cancer Res; 2001 Jul 15; 61(14):5505-10. PubMed ID: 11454699
    [Abstract] [Full Text] [Related]

  • 20. Effect of the combined treatment with 5-fluorouracil, gamma-interferon or folinic acid on carcinoembryonic antigen expression in colon cancer cells.
    Aquino A, Prete SP, Greiner JW, Giuliani A, Graziani G, Turriziani M, De Filippi R, Masci G, Bonmassar E, De Vecchis L.
    Clin Cancer Res; 1998 Oct 15; 4(10):2473-81. PubMed ID: 9796980
    [Abstract] [Full Text] [Related]

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