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652 related items for PubMed ID: 8479540

  • 1. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.
    Rozakis-Adcock M, Fernley R, Wade J, Pawson T, Bowtell D.
    Nature; 1993 May 06; 363(6424):83-5. PubMed ID: 8479540
    [Abstract] [Full Text] [Related]

  • 2. Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.
    Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J.
    Nature; 1993 May 06; 363(6424):85-8. PubMed ID: 8479541
    [Abstract] [Full Text] [Related]

  • 3. MAP kinase phosphorylation of mSos1 promotes dissociation of mSos1-Shc and mSos1-EGF receptor complexes.
    Rozakis-Adcock M, van der Geer P, Mbamalu G, Pawson T.
    Oncogene; 1995 Oct 05; 11(7):1417-26. PubMed ID: 7478566
    [Abstract] [Full Text] [Related]

  • 4. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.
    Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA.
    Nature; 1993 May 06; 363(6424):45-51. PubMed ID: 8479536
    [Abstract] [Full Text] [Related]

  • 5. Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras.
    Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, Bar-Sagi D.
    Nature; 1993 May 06; 363(6424):88-92. PubMed ID: 8386805
    [Abstract] [Full Text] [Related]

  • 6. Coupling of the murine protein tyrosine phosphatase PEST to the epidermal growth factor (EGF) receptor through a Src homology 3 (SH3) domain-mediated association with Grb2.
    Charest A, Wagner J, Kwan M, Tremblay ML.
    Oncogene; 1997 Apr 10; 14(14):1643-51. PubMed ID: 9135065
    [Abstract] [Full Text] [Related]

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  • 9. Autophosphorylation mutants of the EGF-receptor signal through auxiliary mechanisms involving SH2 domain proteins.
    Li N, Schlessinger J, Margolis B.
    Oncogene; 1994 Dec 10; 9(12):3457-65. PubMed ID: 7970705
    [Abstract] [Full Text] [Related]

  • 10. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases.
    Rozakis-Adcock M, McGlade J, Mbamalu G, Pelicci G, Daly R, Li W, Batzer A, Thomas S, Brugge J, Pelicci PG, Schlessinger J, Pawson T.
    Nature; 1992 Dec 17; 360(6405):689-92. PubMed ID: 1465135
    [Abstract] [Full Text] [Related]

  • 11. Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2.
    Xu XX, Yi T, Tang B, Lambeth JD.
    Oncogene; 1998 Mar 26; 16(12):1561-9. PubMed ID: 9569023
    [Abstract] [Full Text] [Related]

  • 12. Sos1 rapidly associates with Grb2 and is hypophosphorylated when complexed with the EGF receptor after EGF stimulation.
    Hu Y, Bowtell DD.
    Oncogene; 1996 May 02; 12(9):1865-72. PubMed ID: 8649846
    [Abstract] [Full Text] [Related]

  • 13. Tyrosine kinase signalling pathways.
    Pawson T.
    Princess Takamatsu Symp; 1994 May 02; 24():303-22. PubMed ID: 8983084
    [Abstract] [Full Text] [Related]

  • 14. Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
    Nioche P, Liu WQ, Broutin I, Charbonnier F, Latreille MT, Vidal M, Roques B, Garbay C, Ducruix A.
    J Mol Biol; 2002 Feb 01; 315(5):1167-77. PubMed ID: 11827484
    [Abstract] [Full Text] [Related]

  • 15. SH2 domain specificity and activity modified by a single residue.
    Marengere LE, Songyang Z, Gish GD, Schaller MD, Parsons JT, Stern MJ, Cantley LC, Pawson T.
    Nature; 1994 Jun 09; 369(6480):502-5. PubMed ID: 7515480
    [Abstract] [Full Text] [Related]

  • 16. A new function for phospholipase C-gamma1: coupling to the adaptor protein GRB2.
    Pei Z, Maloney JA, Yang L, Williamson JR.
    Arch Biochem Biophys; 1997 Sep 01; 345(1):103-10. PubMed ID: 9281317
    [Abstract] [Full Text] [Related]

  • 17. Activation of tyrosine kinases by alpha1A-adrenergic and growth factor receptors in transfected PC12 cells.
    Zhong H, Minneman KP.
    Biochem J; 1999 Dec 15; 344 Pt 3(Pt 3):889-94. PubMed ID: 10585878
    [Abstract] [Full Text] [Related]

  • 18. Role of Shc in the activation of Ras in response to epidermal growth factor and nerve growth factor.
    Basu T, Warne PH, Downward J.
    Oncogene; 1994 Dec 15; 9(12):3483-91. PubMed ID: 7970708
    [Abstract] [Full Text] [Related]

  • 19. Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling.
    Najib S, Sánchez-Margalet V.
    J Cell Biochem; 2002 Dec 15; 86(1):99-106. PubMed ID: 12112020
    [Abstract] [Full Text] [Related]

  • 20. Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor Shc.
    Kranenburg O, Verlaan I, Hordijk PL, Moolenaar WH.
    EMBO J; 1997 Jun 02; 16(11):3097-105. PubMed ID: 9214627
    [Abstract] [Full Text] [Related]

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