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465 related items for PubMed ID: 8479541

  • 1. Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.
    Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J.
    Nature; 1993 May 06; 363(6424):85-8. PubMed ID: 8479541
    [Abstract] [Full Text] [Related]

  • 2. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.
    Rozakis-Adcock M, Fernley R, Wade J, Pawson T, Bowtell D.
    Nature; 1993 May 06; 363(6424):83-5. PubMed ID: 8479540
    [Abstract] [Full Text] [Related]

  • 3. Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras.
    Gale NW, Kaplan S, Lowenstein EJ, Schlessinger J, Bar-Sagi D.
    Nature; 1993 May 06; 363(6424):88-92. PubMed ID: 8386805
    [Abstract] [Full Text] [Related]

  • 4. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.
    Egan SE, Giddings BW, Brooks MW, Buday L, Sizeland AM, Weinberg RA.
    Nature; 1993 May 06; 363(6424):45-51. PubMed ID: 8479536
    [Abstract] [Full Text] [Related]

  • 5. Coupling of the murine protein tyrosine phosphatase PEST to the epidermal growth factor (EGF) receptor through a Src homology 3 (SH3) domain-mediated association with Grb2.
    Charest A, Wagner J, Kwan M, Tremblay ML.
    Oncogene; 1997 Apr 10; 14(14):1643-51. PubMed ID: 9135065
    [Abstract] [Full Text] [Related]

  • 6. A Grb2-associated docking protein in EGF- and insulin-receptor signalling.
    Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK, Wong AJ.
    Nature; 1996 Feb 08; 379(6565):560-4. PubMed ID: 8596638
    [Abstract] [Full Text] [Related]

  • 7. Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling.
    Zhang T, Ma J, Cao X.
    Biochem J; 2003 Dec 01; 376(Pt 2):457-64. PubMed ID: 14498832
    [Abstract] [Full Text] [Related]

  • 8. Autophosphorylation mutants of the EGF-receptor signal through auxiliary mechanisms involving SH2 domain proteins.
    Li N, Schlessinger J, Margolis B.
    Oncogene; 1994 Dec 01; 9(12):3457-65. PubMed ID: 7970705
    [Abstract] [Full Text] [Related]

  • 9. Sos1 rapidly associates with Grb2 and is hypophosphorylated when complexed with the EGF receptor after EGF stimulation.
    Hu Y, Bowtell DD.
    Oncogene; 1996 May 02; 12(9):1865-72. PubMed ID: 8649846
    [Abstract] [Full Text] [Related]

  • 10. Phosphorylation of growth factor receptor binding protein-2 by pp60c-src tyrosine kinase.
    Jones DA, Benjamin CW.
    Arch Biochem Biophys; 1997 Jan 15; 337(2):143-8. PubMed ID: 9016807
    [Abstract] [Full Text] [Related]

  • 11. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases.
    Rozakis-Adcock M, McGlade J, Mbamalu G, Pelicci G, Daly R, Li W, Batzer A, Thomas S, Brugge J, Pelicci PG, Schlessinger J, Pawson T.
    Nature; 1992 Dec 17; 360(6405):689-92. PubMed ID: 1465135
    [Abstract] [Full Text] [Related]

  • 12. Grb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.
    Boerner JL, Danielsen AJ, Lovejoy CA, Wang Z, Juneja SC, Faupel-Badger JM, Darce JR, Maihle NJ.
    Oncogene; 2003 Oct 02; 22(43):6679-89. PubMed ID: 14555981
    [Abstract] [Full Text] [Related]

  • 13. Activation of tyrosine kinases by alpha1A-adrenergic and growth factor receptors in transfected PC12 cells.
    Zhong H, Minneman KP.
    Biochem J; 1999 Dec 15; 344 Pt 3(Pt 3):889-94. PubMed ID: 10585878
    [Abstract] [Full Text] [Related]

  • 14. Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2.
    Janes PW, Daly RJ, deFazio A, Sutherland RL.
    Oncogene; 1994 Dec 15; 9(12):3601-8. PubMed ID: 7970720
    [Abstract] [Full Text] [Related]

  • 15. N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway.
    Nakamura T, Sanokawa R, Sasaki Y, Ayusawa D, Oishi M, Mori N.
    Oncogene; 1996 Sep 19; 13(6):1111-21. PubMed ID: 8808684
    [Abstract] [Full Text] [Related]

  • 16. Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
    Nioche P, Liu WQ, Broutin I, Charbonnier F, Latreille MT, Vidal M, Roques B, Garbay C, Ducruix A.
    J Mol Biol; 2002 Feb 01; 315(5):1167-77. PubMed ID: 11827484
    [Abstract] [Full Text] [Related]

  • 17. A new function for phospholipase C-gamma1: coupling to the adaptor protein GRB2.
    Pei Z, Maloney JA, Yang L, Williamson JR.
    Arch Biochem Biophys; 1997 Sep 01; 345(1):103-10. PubMed ID: 9281317
    [Abstract] [Full Text] [Related]

  • 18. SH2 domain specificity and activity modified by a single residue.
    Marengere LE, Songyang Z, Gish GD, Schaller MD, Parsons JT, Stern MJ, Cantley LC, Pawson T.
    Nature; 1994 Jun 09; 369(6480):502-5. PubMed ID: 7515480
    [Abstract] [Full Text] [Related]

  • 19. Differential response of the Ras exchange factor, Ras-GRF to tyrosine kinase and G protein mediated signals.
    Shou C, Wurmser A, Suen KL, Barbacid M, Feig LA, Ling K.
    Oncogene; 1995 May 18; 10(10):1887-93. PubMed ID: 7761090
    [Abstract] [Full Text] [Related]

  • 20. Tyrosine kinase signalling pathways.
    Pawson T.
    Princess Takamatsu Symp; 1994 May 18; 24():303-22. PubMed ID: 8983084
    [Abstract] [Full Text] [Related]

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