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171 related items for PubMed ID: 8493983

  • 1. Selection of a new generation of orally active alpha-ketohydroxypyridine iron chelators intended for use in the treatment of iron overload.
    Kontoghiorghes GJ, Barr J, Nortey P, Sheppard L.
    Am J Hematol; 1993 Apr; 42(4):340-9. PubMed ID: 8493983
    [Abstract] [Full Text] [Related]

  • 2. Orally active alpha-ketohydroxypyridine iron chelators: studies in mice.
    Kontoghiorghes GJ.
    Mol Pharmacol; 1986 Dec; 30(6):670-3. PubMed ID: 3785144
    [Abstract] [Full Text] [Related]

  • 3. Orally active alpha-ketohydroxypyridine iron chelators: effects on iron and other metal mobilisations.
    Kontoghiorghes GJ.
    Acta Haematol; 1987 Dec; 78(2-3):212-6. PubMed ID: 3120474
    [Abstract] [Full Text] [Related]

  • 4. In vivo evaluation of hydroxypyridone iron chelators in a mouse model.
    Gyparaki M, Porter JB, Hirani S, Streater M, Hider RC, Huehns ER.
    Acta Haematol; 1987 Dec; 78(2-3):217-21. PubMed ID: 3120475
    [Abstract] [Full Text] [Related]

  • 5. Iron chelation studies using desferrioxamine and the potential oral chelator, 1,2-dimethyl-3-hydroxypyrid-4-one, in normal and iron loaded rats.
    Kontoghiorghes GJ, Sheppard L, Hoffbrand AV, Charalambous J, Tikerpae J, Pippard MJ.
    J Clin Pathol; 1987 Apr; 40(4):404-8. PubMed ID: 3584483
    [Abstract] [Full Text] [Related]

  • 6. Dose response studies using desferrioxamine and orally active chelators in a mouse model.
    Kontoghiorghes GJ.
    Scand J Haematol; 1986 Jul; 37(1):63-70. PubMed ID: 3764334
    [Abstract] [Full Text] [Related]

  • 7. Effect of novel 1-alkyl-3-hydroxy-2-methylpyrid-4-one chelators on uptake and release of iron from macrophages.
    Brock JH, Licéaga J, Arthur HM, Kontoghiorghes GJ.
    Am J Hematol; 1990 May; 34(1):21-5. PubMed ID: 2327400
    [Abstract] [Full Text] [Related]

  • 8. Comparative study of iron mobilization from haemosiderin, ferritin and iron(III) precipitates by chelators.
    Kontoghiorghes GJ, Chambers S, Hoffbrand AV.
    Biochem J; 1987 Jan 01; 241(1):87-92. PubMed ID: 3566714
    [Abstract] [Full Text] [Related]

  • 9. Comparative efficacy and toxicity of desferrioxamine, deferiprone and other iron and aluminium chelating drugs.
    Kontoghiorghes GJ.
    Toxicol Lett; 1995 Oct 01; 80(1-3):1-18. PubMed ID: 7482575
    [Abstract] [Full Text] [Related]

  • 10. Effective chelation of iron in beta thalassaemia with the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one.
    Kontoghiorghes GJ, Aldouri MA, Hoffbrand AV, Barr J, Wonke B, Kourouclaris T, Sheppard L.
    Br Med J (Clin Res Ed); 1987 Dec 12; 295(6612):1509-12. PubMed ID: 3122880
    [Abstract] [Full Text] [Related]

  • 11. The effect of 2,4-dihydroxypyridine-N-oxide, a new orally active iron chelator, on iron excretion in mice.
    Kontoghiorghes GJ.
    Clin Chim Acta; 1987 Mar 16; 163(2):137-41. PubMed ID: 3568416
    [Abstract] [Full Text] [Related]

  • 12. Orally active alpha-ketohydroxy pyridine iron chelators intended for clinical use: in vivo studies in rabbits.
    Kontoghiorghes GJ, Hoffbrand AV.
    Br J Haematol; 1986 Apr 16; 62(4):607-13. PubMed ID: 3964556
    [Abstract] [Full Text] [Related]

  • 13. Relative oral efficacy and acute toxicity of hydroxypyridin-4-one iron chelators in mice.
    Porter JB, Morgan J, Hoyes KP, Burke LC, Huehns ER, Hider RC.
    Blood; 1990 Dec 01; 76(11):2389-96. PubMed ID: 2257308
    [Abstract] [Full Text] [Related]

  • 14. Studies of aluminium mobilization in renal dialysis patients using the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one.
    Kontoghiorghes GJ, Barr J, Baillod RA.
    Arzneimittelforschung; 1994 Apr 01; 44(4):522-6. PubMed ID: 8011008
    [Abstract] [Full Text] [Related]

  • 15. PCTH: a novel orally active chelator of the aroylhydrazone class that induces iron excretion from mice.
    Wong CS, Kwok JC, Richardson DR.
    Biochim Biophys Acta; 2004 Dec 24; 1739(1):70-80. PubMed ID: 15607119
    [Abstract] [Full Text] [Related]

  • 16. Site specificity of iron removal from transferrin by alpha-ketohydroxypyridine chelators.
    Kontoghiorghes GJ, Evans RW.
    FEBS Lett; 1985 Sep 09; 189(1):141-4. PubMed ID: 4029396
    [Abstract] [Full Text] [Related]

  • 17. Studies of in vivo iron mobilization by chelators in the ferrocene-loaded rat.
    Florence A, Ward RJ, Peters TJ, Crichton RR.
    Biochem Pharmacol; 1992 Sep 25; 44(6):1023-7. PubMed ID: 1417929
    [Abstract] [Full Text] [Related]

  • 18. New synthetic approach and iron chelating studies of 1-alkyl-2-methyl-3-hydroxypyrid-4-ones.
    Kontoghiorghes GJ, Sheppard L, Chambers S.
    Arzneimittelforschung; 1987 Oct 25; 37(10):1099-102. PubMed ID: 3435580
    [Abstract] [Full Text] [Related]

  • 19. Free radical and cytotoxic effects of chelators and their iron complexes in the hepatocyte.
    Mostert LJ, Van Dorst JA, Koster JF, Van Eijk HG, Kontoghiorghes GJ.
    Free Radic Res Commun; 1987 Oct 25; 3(6):379-88. PubMed ID: 3508452
    [Abstract] [Full Text] [Related]

  • 20. Chelation of aluminium by combining DFO and L1 in rats.
    Blanusa M, Prester L, Varnai VM, Pavlović D, Kostial K, Jones MM, Singh PK.
    Toxicology; 2000 Jul 05; 147(3):151-6. PubMed ID: 10924797
    [Abstract] [Full Text] [Related]

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