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Journal Abstract Search


110 related items for PubMed ID: 8517874

  • 1. Effect of substituting fluorine for hydrogen at C-26 and C-27 on the side chain of 1,25-dihydroxyvitamin D3.
    Inaba M, Okuno S, Nishizawa Y, Imanishi Y, Katsumata T, Sugata I, Morii H.
    Biochem Pharmacol; 1993 Jun 09; 45(11):2331-6. PubMed ID: 8517874
    [Abstract] [Full Text] [Related]

  • 2. Modification of 1 alpha,25-dihydroxyvitamin D3 metabolism by introduction of 26,26,26,27,27,27-hexafluoro atoms in human promyelocytic leukaemia (HL-60) cells: isolation and identification of a novel bioactive metabolite, 26,26,26,27,27,27-hexafluoro-1 alpha,23(S),25-trihydroxyvitamin D3.
    Honda A, Nakashima N, Shida Y, Mori Y, Nagata A, Ishizuka S.
    Biochem J; 1993 Oct 15; 295 ( Pt 2)(Pt 2):509-16. PubMed ID: 8240250
    [Abstract] [Full Text] [Related]

  • 3. Biological activities of 26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3 on human promyelocytic leukemic HL-60 cells: effects of fetal bovine serum and of incubation time.
    Okuno S, Inaba M, Nishizawa Y, Morii H.
    Miner Electrolyte Metab; 1995 Oct 15; 21(1-3):211-6. PubMed ID: 7565452
    [Abstract] [Full Text] [Related]

  • 4. Metabolism of 26,27-hexafluoro-1 alpha,25-dihydroxyvitamin D3 and 26,27-hexafluoro-1 alpha,23(S)25-trihydroxyvitamin D3 in ROS17/2.8 cells transfected with a plasmid expressing CYP24.
    Miyahara T, Gomyo S, Ueda Y, Ohyama Y, Sigeno C, Kozakai A, Takamura T, Yamazaki R, Higuchi S, Yamamoto M, Sakuma T, Nemoto N.
    Xenobiotica; 2000 Nov 15; 30(11):1055-62. PubMed ID: 11197067
    [Abstract] [Full Text] [Related]

  • 5. Comparison of 26,27-hexafluoro-1 alpha,25-dihydroxyvitamin D3 and 1 alpha,25-dihydroxyvitamin D3 on the resorption of bone explants ex vivo.
    Miyahara T, Harada M, Kozakai A, Matsumoto M, Hashimoto K, Inoue H, Yoda K, Nakatsu T, Kajita S, Yamazaki R, Higuchi S, Kozuka H, Nemoto N.
    J Nutr Sci Vitaminol (Tokyo); 1999 Jun 15; 45(3):239-49. PubMed ID: 10524344
    [Abstract] [Full Text] [Related]

  • 6. Effects on cultured neonatal mouse calvaria of 1 alpha,25-dihydroxyvitamin D3, 26,26,26,27,27,27-hexafluoro-1 alpha,25-dihydroxyvitamin D3 and 26,26,26,27,27,27-hexafluoro-1 alpha,23S,25-trihydroxyvitamin D3.
    Harada M, Miyahara T, Miyata M, Tomita I, Okayachi H, Ikemoto Y, Higuchi S, Otomo S, Kozuka H, Ikekawa N.
    Bone Miner; 1992 Jul 15; 18(1):41-9. PubMed ID: 1422297
    [Abstract] [Full Text] [Related]

  • 7. Biological activity of fluorinated vitamin D analogs at C-26 and C-27 on human promyelocytic leukemia cells, HL-60.
    Inaba M, Okuno S, Nishizawa Y, Yukioka K, Otani S, Matsui-Yuasa I, Morisawa S, DeLuca HF, Morii H.
    Arch Biochem Biophys; 1987 Nov 01; 258(2):421-5. PubMed ID: 2823715
    [Abstract] [Full Text] [Related]

  • 8. Effects of vitamin D-binding proteins on HL-60 cell differentiation induced by 26,26,26,27,27,27-hexafluoro-1 alpha,25-dihydroxyvitamin D.
    Honda A, Nakashima N, Mori Y, Katsumata T, Ishizuka S.
    J Steroid Biochem Mol Biol; 1992 Jan 01; 41(1):109-12. PubMed ID: 1310414
    [Abstract] [Full Text] [Related]

  • 9. Effect of a highly potent fluoro analog of 1,25-dihydroxyvitamin D3 on human bone-derived cells.
    Kiriyama T, Okamoto S, Ejima E, Kurihara N, Hakeda Y, Ito N, Izumi M, Kumegawa M, Nagataki S.
    Endocrinology; 1991 Jan 01; 128(1):81-6. PubMed ID: 1846118
    [Abstract] [Full Text] [Related]

  • 10. Increased biological potency of hexafluorinated analogs of 1,25-dihydroxyvitamin D3 on bovine parathyroid cells.
    Imanishi Y, Inaba M, Seki H, Koyama H, Nishizawa Y, Morii H, Otani S.
    J Steroid Biochem Mol Biol; 1999 Jan 01; 70(4-6):243-8. PubMed ID: 10622414
    [Abstract] [Full Text] [Related]

  • 11. A highly potent 26,27-Hexafluoro-1a,25-dihydroxyvitamin D3 on calcification in SV40-transformed human fetal osteoblastic cells.
    Miyahara T, Simoura T, Osahune N, Uchida Y, Sakuma T, Nemoto N, Kozakai A, Takamura T, Yamazaki R, Higuchi S, Chiba H, Iba K, Sawada N.
    Calcif Tissue Int; 2002 Jun 01; 70(6):488-95. PubMed ID: 12016462
    [Abstract] [Full Text] [Related]

  • 12. 1alpha,25-dihydroxyvitamin D3-24-hydroxylase (CYP24) hydroxylates the carbon at the end of the side chain (C-26) of the C-24-fluorinated analog of 1alpha,25-dihydroxyvitamin D3.
    Miyamoto Y, Shinki T, Yamamoto K, Ohyama Y, Iwasaki H, Hosotani R, Kasama T, Takayama H, Yamada S, Suda T.
    J Biol Chem; 1997 May 30; 272(22):14115-9. PubMed ID: 9162038
    [Abstract] [Full Text] [Related]

  • 13. Novel vitamin D3 derivatives, 26-homo-delta 22-dehydro-1 alpha,25(S)-dihydroxyvitamin D3 and 26-homo-delta 22-dehydro-1 alpha,25(R)-dihydroxyvitamin D3: preferential activity in c-myc mRNA production and in induction of phenotypic differentiation of HL-60 cells.
    Koizumi T, Nakao Y, Ishizuka S, Oshida J, Hara N, Ikekawa N, Fijita T.
    Arch Biochem Biophys; 1990 Feb 01; 276(2):310-6. PubMed ID: 2407190
    [Abstract] [Full Text] [Related]

  • 14. C-25 hydroxylation of 1alpha,24(R)-dihydroxyvitamin D3 is catalyzed by 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1): metabolism studies with human keratinocytes and rat recombinant CYP24A1.
    Astecker N, Bobrovnikova EA, Omdahl JL, Gennaro L, Vouros P, Schuster I, Uskokovic MR, Ishizuka S, Wang G, Reddy GS.
    Arch Biochem Biophys; 2004 Nov 15; 431(2):261-70. PubMed ID: 15488475
    [Abstract] [Full Text] [Related]

  • 15. Effect of hexafluoro-1,25-dihydroxyvitamin D3 and sodium butyrate combination on differentiation and proliferation of HL-60 leukemia cells.
    Yoshida M, Tanaka Y, Eguchi T, Ikekawa N, Saijo N.
    Anticancer Res; 1992 Nov 15; 12(6B):1947-52. PubMed ID: 1363510
    [Abstract] [Full Text] [Related]

  • 16. Isolation and identification of 1alpha-hydroxy-24-oxovitamin D3 and 1alpha,23-dihydroxy-24-oxovitamin D3: metabolites of 1alpha,24(R)-dihydroxyvitamin D3 produced in rat kidney.
    Weinstein EA, Rao DS, Siu-Caldera ML, Tserng KY, Uskokovic MR, Ishizuka S, Reddy GS.
    Biochem Pharmacol; 1999 Dec 15; 58(12):1965-73. PubMed ID: 10591152
    [Abstract] [Full Text] [Related]

  • 17. Vitamin D3 analogs: effect on leukemic clonal growth and differentiation, and on serum calcium levels.
    Pakkala S, de Vos S, Elstner E, Rude RK, Uskokovic M, Binderup L, Koeffler HP.
    Leuk Res; 1995 Jan 15; 19(1):65-72. PubMed ID: 7837819
    [Abstract] [Full Text] [Related]

  • 18. Hexafluoro-1,25-dihydroxyvitamin D3 has markedly increased potency in inhibiting proliferation of cultured human keratinocytes compared with 1,25-dihydroxyvitamin D3.
    Chen TC, Holick MF.
    Br J Dermatol; 2000 Jul 15; 143(1):72-8. PubMed ID: 10886138
    [Abstract] [Full Text] [Related]

  • 19. 26,27-Hexafluoro-1,25-dihydroxyvitamin D3 (F6-1,25(OH)2D3) prevents osteoporosis induced by immobilization combined with ovariectomy in the rat.
    Okumura H, Yamamuro T, Higuchi S, Harada M, Takamura T, Otomo S, Aihara H, Ikekawa N, Kobayashi T.
    Bone Miner; 1990 May 15; 9(2):101-9. PubMed ID: 2350614
    [Abstract] [Full Text] [Related]

  • 20. Regulation of vitamin D-responsive gene expression by fluorinated analogs of calcitriol in rat osteoblastic ROB-C26 cells.
    Miyamoto Y, Shinki T, Ohyama Y, Kasama T, Iwasaki H.
    J Biochem; 1995 Nov 15; 118(5):1068-76. PubMed ID: 8749328
    [Abstract] [Full Text] [Related]


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