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100 related items for PubMed ID: 8521419

  • 1. O6-alkylguanine-DNA alkyltransferase attenuates triazene-induced cytotoxicity and tumor cell immunogenicity in murine L1210 leukemia.
    Graziani G, Faraoni I, Grohmann U, Bianchi R, Binaglia L, Margison GP, Watson AJ, Orlando L, Bonmassar E, D'Atri S.
    Cancer Res; 1995 Dec 15; 55(24):6231-6. PubMed ID: 8521419
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  • 2. In vitro inactivation of human O6-alkylguanine DNA alkyltransferase by antitumor triazene compounds.
    Lacal PM, D'Atri S, Orlando L, Bonmassar E, Graziani G.
    J Pharmacol Exp Ther; 1996 Oct 15; 279(1):416-22. PubMed ID: 8859021
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  • 3. Triazene compounds induce apoptosis in O6-alkylguanine-DNA alkyltransferase deficient leukemia cell lines.
    Tentori L, Graziani G, Gilberti S, Lacal PM, Bonmassar E, D'Atri S.
    Leukemia; 1995 Nov 15; 9(11):1888-95. PubMed ID: 7475280
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  • 7. Cisplatin increases sensitivity of human leukemic blasts to triazene compounds.
    Piccioni D, D'Atri S, Papa G, Caravita T, Franchi A, Bonmassar E, Graziani G.
    J Chemother; 1995 Jun 15; 7(3):224-9. PubMed ID: 7562019
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  • 8. O(6)-benzylguanine enhances the in vitro immunotoxic activity of temozolomide on natural or antigen-dependent immunity.
    Alvino E, Pepponi R, Pagani E, Lacal PM, Nunziata C, Bonmassar E, D'Atri S.
    J Pharmacol Exp Ther; 1999 Dec 15; 291(3):1292-300. PubMed ID: 10565854
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  • 9. [Modulation of the antitumor activity of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosoure a by O(6)-methyl-2'-deoxyguanosine--a new inhibitor of O(6)-alkylguanine-DNA-alkyltransferase].
    Dederer LIu, Sokolova IS, Bakhmedova AA, Miniker TD, Mel'nik SIa, Gorbacheva LB.
    Biokhimiia; 1995 Sep 15; 60(9):1521-9. PubMed ID: 8562657
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  • 10. Protection of mammalian cells against chloroethylating agent toxicity by an O6-benzylguanine-resistant mutant of human O6-alkylguanine-DNA alkyltransferase.
    Hickson I, Fairbairn LJ, Chinnasamy N, Dexter TM, Margison GP, Rafferty JA.
    Gene Ther; 1996 Oct 15; 3(10):868-77. PubMed ID: 8908500
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  • 11. DNA repair enzymes and cytotoxic effects of temozolomide: comparative studies between tumor cells and normal cells of the immune system.
    Pagani E, Pepponi R, Fuggetta MP, Prete SP, Turriziani M, Bonmassar L, Lacal PM, Falcinelli S, Passarelli F, Guadagni F, Alvino E, D'Atri S.
    J Chemother; 2003 Apr 15; 15(2):173-83. PubMed ID: 12797396
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  • 13. Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro.
    Hickson I, Fairbairn LJ, Chinnasamy N, Lashford LS, Thatcher N, Margison GP, Dexter TM, Rafferty JA.
    Gene Ther; 1998 Jun 15; 5(6):835-41. PubMed ID: 9747464
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  • 14. Influence of O6-methylguanine on DNA damage and cytotoxicity of temozolomide in L1210 mouse leukemia sensitive and resistant to chloroethylnitrosoureas.
    Taverna P, Catapano CV, Citti L, Bonfanti M, D'Incalci M.
    Anticancer Drugs; 1992 Aug 15; 3(4):401-5. PubMed ID: 1421437
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  • 16. The effect of O6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide, 1,3-bis(2-chloroethyl)1-nitrosourea, and cisplatin.
    Pepponi R, Marra G, Fuggetta MP, Falcinelli S, Pagani E, Bonmassar E, Jiricny J, D'Atri S.
    J Pharmacol Exp Ther; 2003 Feb 15; 304(2):661-8. PubMed ID: 12538819
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  • 17. Recombinant adeno-associated virus-mediated expression of O6-alkylguanine-DNA-alkyltransferase protects human epithelial and hematopoietic cells against chloroethylating agent toxicity.
    Longhurst SJ, Rafferty JA, Arrand JR, Cortez N, Giraud C, Berns KI, Fairbairn LJ.
    Hum Gene Ther; 1999 Jan 20; 10(2):301-10. PubMed ID: 10022554
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  • 18. Potentiation of nitrosourea cytotoxicity in human leukemic cells by inactivation of O6-alkylguanine-DNA alkyltransferase.
    Gerson SL, Trey JE, Miller K.
    Cancer Res; 1988 Mar 15; 48(6):1521-7. PubMed ID: 3162197
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  • 19. Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.
    Dolan ME, Mitchell RB, Mummert C, Moschel RC, Pegg AE.
    Cancer Res; 1991 Jul 01; 51(13):3367-72. PubMed ID: 1647266
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  • 20. Mutation of the mismatch repair gene hMSH2 and hMSH6 in a human T-cell leukemia line tolerant to methylating agents.
    Levati L, Marra G, Lettieri T, D'Atri S, Vernole P, Tentori L, Lacal PM, Pagani E, Bonmassar E, Jiricny J, Graziani G.
    Genes Chromosomes Cancer; 1998 Oct 01; 23(2):159-66. PubMed ID: 9739019
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