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140 related items for PubMed ID: 8524831

  • 1. Structural and functional analysis of pp70S6k.
    Cheatham L, Monfar M, Chou MM, Blenis J.
    Proc Natl Acad Sci U S A; 1995 Dec 05; 92(25):11696-700. PubMed ID: 8524831
    [Abstract] [Full Text] [Related]

  • 2. Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP.
    Monfar M, Lemon KP, Grammer TC, Cheatham L, Chung J, Vlahos CJ, Blenis J.
    Mol Cell Biol; 1995 Jan 05; 15(1):326-37. PubMed ID: 7528328
    [Abstract] [Full Text] [Related]

  • 3. The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.
    Chou MM, Blenis J.
    Cell; 1996 May 17; 85(4):573-83. PubMed ID: 8653792
    [Abstract] [Full Text] [Related]

  • 4. PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase.
    Chung J, Grammer TC, Lemon KP, Kazlauskas A, Blenis J.
    Nature; 1994 Jul 07; 370(6484):71-5. PubMed ID: 8015612
    [Abstract] [Full Text] [Related]

  • 5. Activation of MAP kinases, pp90rsk and pp70-S6 kinases in mouse mast cells by signaling through the c-kit receptor tyrosine kinase or Fc epsilon RI: rapamycin inhibits activation of pp70-S6 kinase and proliferation in mouse mast cells.
    Tsai M, Chen RH, Tam SY, Blenis J, Galli SJ.
    Eur J Immunol; 1993 Dec 07; 23(12):3286-91. PubMed ID: 7504992
    [Abstract] [Full Text] [Related]

  • 6. The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases.
    Dennis PB, Pullen N, Kozma SC, Thomas G.
    Mol Cell Biol; 1996 Nov 07; 16(11):6242-51. PubMed ID: 8887654
    [Abstract] [Full Text] [Related]

  • 7. Multiple independent inputs are required for activation of the p70 S6 kinase.
    Weng QP, Andrabi K, Kozlowski MT, Grove JR, Avruch J.
    Mol Cell Biol; 1995 May 07; 15(5):2333-40. PubMed ID: 7739516
    [Abstract] [Full Text] [Related]

  • 8. Studies of partially transforming polyomavirus mutants establish a role for phosphatidylinositol 3-kinase in activation of pp70 S6 kinase.
    Dahl J, Freund R, Blenis J, Benjamin TL.
    Mol Cell Biol; 1996 Jun 07; 16(6):2728-35. PubMed ID: 8649380
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of p70/p85 S6 kinase activities in T cells by dexamethasone.
    Monfar M, Blenis J.
    Mol Endocrinol; 1996 Sep 07; 10(9):1107-15. PubMed ID: 8885245
    [Abstract] [Full Text] [Related]

  • 10. Rapamycin resistance in ataxia-telangiectasia.
    Beamish H, Williams R, Chen P, Khanna KK, Hobson K, Watters D, Shiloh Y, Lavin M.
    Oncogene; 1996 Sep 05; 13(5):963-70. PubMed ID: 8806686
    [Abstract] [Full Text] [Related]

  • 11. Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1.
    Phin S, Kupferwasser D, Lam J, Lee-Fruman KK.
    Biochem J; 2003 Jul 15; 373(Pt 2):583-91. PubMed ID: 12713446
    [Abstract] [Full Text] [Related]

  • 12. Growth factor-dependent survival of rodent fibroblasts requires phosphatidylinositol 3-kinase but is independent of pp70S6K activity.
    Yao R, Cooper GM.
    Oncogene; 1996 Jul 18; 13(2):343-51. PubMed ID: 8710373
    [Abstract] [Full Text] [Related]

  • 13. Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites.
    Han JW, Pearson RB, Dennis PB, Thomas G.
    J Biol Chem; 1995 Sep 08; 270(36):21396-403. PubMed ID: 7545671
    [Abstract] [Full Text] [Related]

  • 14. Nerve growth factor-stimulated nuclear S6 kinase in PC12 cells.
    Tang T, Hirata Y, Whalin M, Guroff G.
    J Neurochem; 1996 Mar 08; 66(3):1198-206. PubMed ID: 8769884
    [Abstract] [Full Text] [Related]

  • 15. A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells.
    Scott PH, Belham CM, al-Hafidh J, Chilvers ER, Peacock AJ, Gould GW, Plevin R.
    Biochem J; 1996 Sep 15; 318 ( Pt 3)(Pt 3):965-71. PubMed ID: 8836145
    [Abstract] [Full Text] [Related]

  • 16. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases.
    Chung J, Kuo CJ, Crabtree GR, Blenis J.
    Cell; 1992 Jun 26; 69(7):1227-36. PubMed ID: 1377606
    [Abstract] [Full Text] [Related]

  • 17. The serine protease inhibitors, tosylphenylalanine chloromethyl ketone and tosyllysine chloromethyl ketone, potently inhibit pp70s6k activation.
    Grammer TC, Blenis J.
    J Biol Chem; 1996 Sep 27; 271(39):23650-2. PubMed ID: 8798584
    [Abstract] [Full Text] [Related]

  • 18. The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf.
    Cross DA, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, Cohen P.
    Biochem J; 1994 Oct 01; 303 ( Pt 1)(Pt 1):21-6. PubMed ID: 7945242
    [Abstract] [Full Text] [Related]

  • 19. 4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase.
    von Manteuffel SR, Gingras AC, Ming XF, Sonenberg N, Thomas G.
    Proc Natl Acad Sci U S A; 1996 Apr 30; 93(9):4076-80. PubMed ID: 8633019
    [Abstract] [Full Text] [Related]

  • 20. Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation.
    Calvo V, Wood M, Gjertson C, Vik T, Bierer BE.
    Eur J Immunol; 1994 Nov 30; 24(11):2664-71. PubMed ID: 7957559
    [Abstract] [Full Text] [Related]

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