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389 related items for PubMed ID: 8524860
1. Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel. Qu Y, Rogers J, Tanada T, Scheuer T, Catterall WA. Proc Natl Acad Sci U S A; 1995 Dec 05; 92(25):11839-43. PubMed ID: 8524860 [Abstract] [Full Text] [Related]
2. A critical residue for isoform difference in tetrodotoxin affinity is a molecular determinant of the external access path for local anesthetics in the cardiac sodium channel. Sunami A, Glaaser IW, Fozzard HA. Proc Natl Acad Sci U S A; 2000 Feb 29; 97(5):2326-31. PubMed ID: 10681444 [Abstract] [Full Text] [Related]
3. Sodium channel selectivity filter regulates antiarrhythmic drug binding. Sunami A, Dudley SC, Fozzard HA. Proc Natl Acad Sci U S A; 1997 Dec 09; 94(25):14126-31. PubMed ID: 9391164 [Abstract] [Full Text] [Related]
6. Cardiac-specific external paths for lidocaine, defined by isoform-specific residues, accelerate recovery from use-dependent block. Lee PJ, Sunami A, Fozzard HA. Circ Res; 2001 Nov 23; 89(11):1014-21. PubMed ID: 11717158 [Abstract] [Full Text] [Related]
9. Unexpected mexiletine responses of a mutant cardiac Na+ channel implicate the selectivity filter as a structural determinant of antiarrhythmic drug access. Sasaki K, Makita N, Sunami A, Sakurada H, Shirai N, Yokoi H, Kimura A, Tohse N, Hiraoka M, Kitabatake A. Mol Pharmacol; 2004 Aug 23; 66(2):330-6. PubMed ID: 15266024 [Abstract] [Full Text] [Related]
12. Differential interaction of R-mexiletine with the local anesthetic receptor site on brain and heart sodium channel alpha-subunits. Weiser T, Qu Y, Catterall WA, Scheuer T. Mol Pharmacol; 1999 Dec 23; 56(6):1238-44. PubMed ID: 10570051 [Abstract] [Full Text] [Related]
15. Delimiting the binding site for quaternary ammonium lidocaine derivatives in the acetylcholine receptor channel. Pascual JM, Karlin A. J Gen Physiol; 1998 Nov 23; 112(5):611-21. PubMed ID: 9806969 [Abstract] [Full Text] [Related]
17. A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated mu1 Na+ channels. Wang GK, Quan C, Wang S. Pflugers Arch; 1998 Jan 23; 435(2):293-302. PubMed ID: 9382945 [Abstract] [Full Text] [Related]
18. Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits. Qu Y, Rogers JC, Chen SF, McCormick KA, Scheuer T, Catterall WA. J Biol Chem; 1999 Nov 12; 274(46):32647-54. PubMed ID: 10551819 [Abstract] [Full Text] [Related]