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Journal Abstract Search


254 related items for PubMed ID: 8525474

  • 1. Activation of extracellular signal-regulated protein kinase (ERK/MAP kinase) following CD28 cross-linking: activation in cells lacking p56lck.
    August A, Dupont B.
    Tissue Antigens; 1995 Sep; 46(3 ( Pt 1)):155-62. PubMed ID: 8525474
    [Abstract] [Full Text] [Related]

  • 2. Uncoupling activation-dependent HS1 phosphorylation from nuclear factor of activated T cells transcriptional activation in Jurkat T cells: differential signaling through CD3 and the costimulatory receptors CD2 and CD28.
    Hutchcroft JE, Slavik JM, Lin H, Watanabe T, Bierer BE.
    J Immunol; 1998 Nov 01; 161(9):4506-12. PubMed ID: 9794375
    [Abstract] [Full Text] [Related]

  • 3. The EMT/ITK/TSK (EMT) tyrosine kinase is activated during TCR signaling: LCK is required for optimal activation of EMT.
    Gibson S, August A, Kawakami Y, Kawakami T, Dupont B, Mills GB.
    J Immunol; 1996 Apr 15; 156(8):2716-22. PubMed ID: 8609388
    [Abstract] [Full Text] [Related]

  • 4. CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line.
    August A, Gibson S, Kawakami Y, Kawakami T, Mills GB, Dupont B.
    Proc Natl Acad Sci U S A; 1994 Sep 27; 91(20):9347-51. PubMed ID: 7524075
    [Abstract] [Full Text] [Related]

  • 5. p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation.
    Raab M, Cai YC, Bunnell SC, Heyeck SD, Berg LJ, Rudd CE.
    Proc Natl Acad Sci U S A; 1995 Sep 12; 92(19):8891-5. PubMed ID: 7568038
    [Abstract] [Full Text] [Related]

  • 6. Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK.
    Gibson S, Truitt K, Lu Y, Lapushin R, Khan H, Imboden JB, Mills GB.
    Biochem J; 1998 Mar 15; 330 ( Pt 3)(Pt 3):1123-8. PubMed ID: 9494076
    [Abstract] [Full Text] [Related]

  • 7. Activation of src family kinase lck following CD28 crosslinking in the Jurkat leukemic cell line.
    August A, Dupont B.
    Biochem Biophys Res Commun; 1994 Mar 30; 199(3):1466-73. PubMed ID: 8147892
    [Abstract] [Full Text] [Related]

  • 8. Functional LCK Is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ITK.
    Gibson S, August A, Branch D, Dupont B, Mills GM.
    J Biol Chem; 1996 Mar 22; 271(12):7079-83. PubMed ID: 8636141
    [Abstract] [Full Text] [Related]

  • 9. CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells.
    Appleman LJ, van Puijenbroek AA, Shu KM, Nadler LM, Boussiotis VA.
    J Immunol; 2002 Mar 15; 168(6):2729-36. PubMed ID: 11884439
    [Abstract] [Full Text] [Related]

  • 10. Up-regulated expression of MICA on activated T lymphocytes involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase, and calcineurin.
    Molinero LL, Fuertes MB, Fainboim L, Rabinovich GA, Zwirner NW.
    J Leukoc Biol; 2003 Jun 15; 73(6):815-22. PubMed ID: 12773514
    [Abstract] [Full Text] [Related]

  • 11. CD28 of T lymphocytes associates with phosphatidylinositol 3-kinase.
    August A, Dupont B.
    Int Immunol; 1994 May 15; 6(5):769-74. PubMed ID: 8080844
    [Abstract] [Full Text] [Related]

  • 12. Phosphatidylinositol 3-kinase is required for CD28 but not CD3 regulation of the TEC family tyrosine kinase EMT/ITK/TSK: functional and physical interaction of EMT with phosphatidylinositol 3-kinase.
    Lu Y, Cuevas B, Gibson S, Khan H, LaPushin R, Imboden J, Mills GB.
    J Immunol; 1998 Nov 15; 161(10):5404-12. PubMed ID: 9820515
    [Abstract] [Full Text] [Related]

  • 13. T-Cell receptor signaling pathway exerts a negative control on thrombin-mediated increase in [Ca2+]i and p38 MAPK activation in Jurkat T cells: implication of the tyrosine kinase p56Lck.
    Maulon L, Guérin S, Ricci JE, Breittmayer DF, Auberger P.
    Blood; 1998 Jun 01; 91(11):4232-41. PubMed ID: 9596671
    [Abstract] [Full Text] [Related]

  • 14. Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.
    Nishina H, Bachmann M, Oliveira-dos-Santos AJ, Kozieradzki I, Fischer KD, Odermatt B, Wakeham A, Shahinian A, Takimoto H, Bernstein A, Mak TW, Woodgett JR, Ohashi PS, Penninger JM.
    J Exp Med; 1997 Sep 15; 186(6):941-53. PubMed ID: 9294148
    [Abstract] [Full Text] [Related]

  • 15. Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells.
    Tao L, Wadsworth S, Mercer J, Mueller C, Lynn K, Siekierka J, August A.
    Biochem J; 2002 Apr 01; 363(Pt 1):175-82. PubMed ID: 11903060
    [Abstract] [Full Text] [Related]

  • 16. Analysis of CD28 cytoplasmic tail tyrosine residues as regulators and substrates for the protein tyrosine kinases, EMT and LCK.
    King PD, Sadra A, Teng JM, Xiao-Rong L, Han A, Selvakumar A, August A, Dupont B.
    J Immunol; 1997 Jan 15; 158(2):580-90. PubMed ID: 8992971
    [Abstract] [Full Text] [Related]

  • 17. Tec kinase is involved in transcriptional regulation of IL-2 and IL-4 in the CD28 pathway.
    Yang WC, Olive D.
    Eur J Immunol; 1999 Jun 15; 29(6):1842-9. PubMed ID: 10382746
    [Abstract] [Full Text] [Related]

  • 18. T cell receptor-stimulated generation of hydrogen peroxide inhibits MEK-ERK activation and lck serine phosphorylation.
    Kwon J, Devadas S, Williams MS.
    Free Radic Biol Med; 2003 Aug 15; 35(4):406-17. PubMed ID: 12899942
    [Abstract] [Full Text] [Related]

  • 19. MHC class I ligation of human T cells activates the ZAP70 and p56lck tyrosine kinases, leads to an alternative phenotype of the TCR/CD3 zeta-chain, and induces apoptosis.
    Skov S, Bregenholt S, Claesson MH.
    J Immunol; 1997 Apr 01; 158(7):3189-96. PubMed ID: 9120273
    [Abstract] [Full Text] [Related]

  • 20. Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase.
    Fuertes MB, Molinero LL, Toscano MA, Ilarregui JM, Rubinstein N, Fainboim L, Zwirner NW, Rabinovich GA.
    Mol Cell Biochem; 2004 Dec 01; 267(1-2):177-85. PubMed ID: 15663199
    [Abstract] [Full Text] [Related]


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