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Journal Abstract Search

113 related items for PubMed ID: 8527458

  • 1. Differential effects of ethyl 5-amino-2-methyl-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl carbamate analogs modified at position C2 on tubulin polymerization, binding, and conformational changes.
    Barbier P, Peyrot V, Sarrazin M, Rener GA, Briand C.
    Biochemistry; 1995 Dec 26; 34(51):16821-9. PubMed ID: 8527458
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  • 3. Kinetics of association and dissociation of two enantiomers, NSC 613863 (R)-(+) and NSC 613862 (S)-(-) (CI 980), to tubulin.
    Barbier P, Peyrot V, Dumortier C, D'Hoore A, Rener GA, Engelborghs Y.
    Biochemistry; 1996 Feb 13; 35(6):2008-15. PubMed ID: 8639685
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  • 5. Linkages in tubulin-colchicine functions: the role of the ring C (C') oxygens and ring B in the controls.
    Pérez-Ramírez B, Gorbunoff MJ, Timasheff SN.
    Biochemistry; 1998 Feb 10; 37(6):1646-61. PubMed ID: 9484236
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  • 6. Tubulin binding of two 1-deaza-7,8-dihydropteridines with different biological properties: enantiomers NSC 613862 (S)-(-) and NSC 613863 (R)-(+).
    Leynadier D, Peyrot V, Sarrazin M, Briand C, Andreu JM, Rener GA, Temple C.
    Biochemistry; 1993 Oct 12; 32(40):10675-82. PubMed ID: 8399213
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  • 7. Perturbation of microtubule polymerization by quercetin through tubulin binding: a novel mechanism of its antiproliferative activity.
    Gupta K, Panda D.
    Biochemistry; 2002 Oct 29; 41(43):13029-38. PubMed ID: 12390030
    [Abstract] [Full Text] [Related]

  • 8. Antimitotic agents: ring analogues and derivatives of ethyl [(S)-5-amino-1,2-dihydro-2-methyl-3-phenylpyrido[3,4-b]pyrazin-7- yl]carbamate.
    Temple C, Rener GA.
    J Med Chem; 1992 Dec 25; 35(26):4809-12. PubMed ID: 1479582
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  • 9. Tubulin binding properties of two chiral isomers with 1-deaza-7,8-dihydropteridine structure.
    Leynadier D, Peyrot V, Sarrazin M, Andreu JM, Temple C, Rener G, Briand C.
    Adv Exp Med Biol; 1993 Dec 25; 338():465-8. PubMed ID: 8304159
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  • 10. Antimitotic agents. Chiral isomers of ethyl [5-amino-1,2-dihydro-3-(4-hydroxyphenyl)-2-methylpyrido[3,4-b]pyrazin-7 -yl]carbamate.
    Temple C, Rener GA.
    J Med Chem; 1992 Mar 20; 35(6):988-93. PubMed ID: 1552512
    [Abstract] [Full Text] [Related]

  • 11. Molecular interaction of tubulin with 1-deaza-7,8-dihydropteridines: a comparative study of enantiomers NSC 613862 (S) and NSC 613863 (R) by Raman and Fourier transform infrared spectroscopy.
    Allam N, Millot JM, Manfait M, Leynadier D, Peyrot V, Briand C, Temple C.
    Int J Biol Macromol; 1995 Feb 20; 17(1):55-60. PubMed ID: 7772564
    [Abstract] [Full Text] [Related]

  • 12. Mechanism of colchicine binding to tubulin. Tolerance of substituents in ring C' of biphenyl analogues.
    Andreu JM, Gorbunoff MJ, Medrano FJ, Rossi M, Timasheff SN.
    Biochemistry; 1991 Apr 16; 30(15):3777-86. PubMed ID: 2015233
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  • 13. The colchicine-induced GTPase activity of tubulin: state of the product. Activation by microtubule-promoting cosolvents.
    Perez-Ramirez B, Shearwin KE, Timasheff SN.
    Biochemistry; 1994 May 24; 33(20):6253-61. PubMed ID: 8193140
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  • 14. Differential effects of active isomers, segments, and analogs of dolastatin 10 on ligand interactions with tubulin. Correlation with cytotoxicity.
    Bai R, Roach MC, Jayaram SK, Barkoczy J, Pettit GR, Ludueña RF, Hamel E.
    Biochem Pharmacol; 1993 Apr 06; 45(7):1503-15. PubMed ID: 8471072
    [Abstract] [Full Text] [Related]

  • 15. Characterization of the interaction of TZT-1027, a potent antitumor agent, with tubulin.
    Natsume T, Watanabe J, Tamaoki S, Fujio N, Miyasaka K, Kobayashi M.
    Jpn J Cancer Res; 2000 Jul 06; 91(7):737-47. PubMed ID: 10920282
    [Abstract] [Full Text] [Related]

  • 16. Roles of colchicine rings B and C in the binding process to tubulin.
    Medrano FJ, Andreu JM, Gorbunoff MJ, Timasheff SN.
    Biochemistry; 1989 Jun 27; 28(13):5589-99. PubMed ID: 2775723
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  • 17. Interaction of tubulin with bifunctional colchicine analogues: an equilibrium study.
    Andreu JM, Gorbunoff MJ, Lee JC, Timasheff SN.
    Biochemistry; 1984 Apr 10; 23(8):1742-52. PubMed ID: 6722122
    [Abstract] [Full Text] [Related]

  • 18. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
    Gupta K, Bishop J, Peck A, Brown J, Wilson L, Panda D.
    Biochemistry; 2004 Jun 01; 43(21):6645-55. PubMed ID: 15157098
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