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Journal Abstract Search

124 related items for PubMed ID: 8530359

  • 1. The high activity of rat glutathione transferase 8-8 with alkene substrates is dependent on a glycine residue in the active site.
    Björnestedt R, Tardioli S, Mannervik B.
    J Biol Chem; 1995 Dec 15; 270(50):29705-9. PubMed ID: 8530359
    [Abstract] [Full Text] [Related]

  • 2. Redesign of substrate-selectivity determining modules of glutathione transferase A1-1 installs high catalytic efficiency with toxic alkenal products of lipid peroxidation.
    Nilsson LO, Gustafsson A, Mannervik B.
    Proc Natl Acad Sci U S A; 2000 Aug 15; 97(17):9408-12. PubMed ID: 10900265
    [Abstract] [Full Text] [Related]

  • 3. Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products.
    Bruns CM, Hubatsch I, Ridderström M, Mannervik B, Tainer JA.
    J Mol Biol; 1999 May 07; 288(3):427-39. PubMed ID: 10329152
    [Abstract] [Full Text] [Related]

  • 4. Modular mutagenesis of exons 1, 2, and 8 of a glutathione S-transferase from the mu class. Mechanistic and structural consequences for chimeras of isoenzyme 3-3.
    Zhang P, Liu S, Shan SO, Ji X, Gilliland GL, Armstrong RN.
    Biochemistry; 1992 Oct 27; 31(42):10185-93. PubMed ID: 1420140
    [Abstract] [Full Text] [Related]

  • 5. Involvement of the carboxyl groups of glutathione in the catalytic mechanism of human glutathione transferase A1-1.
    Widersten M, Björnestedt R, Mannervik B.
    Biochemistry; 1996 Jun 18; 35(24):7731-42. PubMed ID: 8672473
    [Abstract] [Full Text] [Related]

  • 6. A comparison of the enzymatic and physicochemical properties of human glutathione transferase M4-4 and three other human Mu class enzymes.
    Comstock KE, Widersten M, Hao XY, Henner WD, Mannervik B.
    Arch Biochem Biophys; 1994 Jun 18; 311(2):487-95. PubMed ID: 8203914
    [Abstract] [Full Text] [Related]

  • 7. Rat glutathione S-transferase M4-4: an isoenzyme with unique structural features including a redox-reactive cysteine-115 residue that forms mixed disulphides with glutathione.
    Cheng H, Tchaikovskaya T, Tu YS, Chapman J, Qian B, Ching WM, Tien M, Rowe JD, Patskovsky YV, Listowsky I, Tu CP.
    Biochem J; 2001 Jun 01; 356(Pt 2):403-14. PubMed ID: 11368767
    [Abstract] [Full Text] [Related]

  • 8. Residue 234 is a master switch of the alternative-substrate activity profile of human and rodent theta class glutathione transferase T1-1.
    Shokeer A, Mannervik B.
    Biochim Biophys Acta; 2010 Apr 01; 1800(4):466-73. PubMed ID: 20097269
    [Abstract] [Full Text] [Related]

  • 9. Glutathione S-transferase class Kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue.
    Pemble SE, Wardle AF, Taylor JB.
    Biochem J; 1996 Nov 01; 319 ( Pt 3)(Pt 3):749-54. PubMed ID: 8920976
    [Abstract] [Full Text] [Related]

  • 10. Structural determinants of glutathione transferases with azathioprine activity identified by DNA shuffling of alpha class members.
    Kurtovic S, Modén O, Shokeer A, Mannervik B.
    J Mol Biol; 2008 Feb 01; 375(5):1365-79. PubMed ID: 18155239
    [Abstract] [Full Text] [Related]

  • 11. A conserved N-capping motif contributes significantly to the stabilization and dynamics of the C-terminal region of class Alpha glutathione S-transferases.
    Dirr HW, Little T, Kuhnert DC, Sayed Y.
    J Biol Chem; 2005 May 20; 280(20):19480-7. PubMed ID: 15757902
    [Abstract] [Full Text] [Related]

  • 12. Protein engineering studies of dichloromethane dehalogenase/glutathione S-transferase from Methylophilus sp. strain DM11. Ser12 but not Tyr6 is required for enzyme activity.
    Vuilleumier S, Leisinger T.
    Eur J Biochem; 1996 Jul 15; 239(2):410-7. PubMed ID: 8706748
    [Abstract] [Full Text] [Related]

  • 13. Characterization of chicken-liver glutathione S-transferase (GST) A1-1 and A2-2 isoenzymes and their site-directed mutants heterologously expressed in Escherichia coli: identification of Lys-15 and Ser-208 on cGSTA1-1 as residues interacting with ethacrynic acid.
    Liu LF, Liaw YC, Tam MF.
    Biochem J; 1997 Oct 15; 327 ( Pt 2)(Pt 2):593-600. PubMed ID: 9359434
    [Abstract] [Full Text] [Related]

  • 14. Isolation and characterization of glutathione S-transferase isozymes from sorghum.
    Gronwald JW, Plaisance KL.
    Plant Physiol; 1998 Jul 15; 117(3):877-92. PubMed ID: 9662530
    [Abstract] [Full Text] [Related]

  • 15. Structure-activity relationships of 4-hydroxyalkenals in the conjugation catalysed by mammalian glutathione transferases.
    Danielson UH, Esterbauer H, Mannervik B.
    Biochem J; 1987 Nov 01; 247(3):707-13. PubMed ID: 3426557
    [Abstract] [Full Text] [Related]

  • 16. Shifting substrate specificity of human glutathione transferase (from class Pi to class alpha) by a single point mutation.
    Nuccetelli M, Mazzetti AP, Rossjohn J, Parker MW, Board P, Caccuri AM, Federici G, Ricci G, Lo Bello M.
    Biochem Biophys Res Commun; 1998 Nov 09; 252(1):184-9. PubMed ID: 9813167
    [Abstract] [Full Text] [Related]

  • 17. Effects of directed mutagenesis on conserved arginine residues in a human Class Alpha glutathione transferase.
    Stenberg G, Board PG, Carlberg I, Mannervik B.
    Biochem J; 1991 Mar 01; 274 ( Pt 2)(Pt 2):549-55. PubMed ID: 2006917
    [Abstract] [Full Text] [Related]

  • 18. Purification and characterization of glutathione S-transferase of murine ovary and testis.
    Awasthi S, Singhal SS, Srivastava SK, Awasthi YC.
    Arch Biochem Biophys; 1993 Feb 15; 301(1):143-50. PubMed ID: 8442656
    [Abstract] [Full Text] [Related]

  • 19. Molecular cloning, expression and site-directed mutagenesis of glutathione S-transferase from Ochrobactrum anthropi.
    Favaloro B, Tamburro A, Angelucci S, Luca AD, Melino S, di Ilio C, Rotilio D.
    Biochem J; 1998 Nov 01; 335 ( Pt 3)(Pt 3):573-9. PubMed ID: 9794797
    [Abstract] [Full Text] [Related]

  • 20. Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases.
    Berhane K, Widersten M, Engström A, Kozarich JW, Mannervik B.
    Proc Natl Acad Sci U S A; 1994 Feb 15; 91(4):1480-4. PubMed ID: 8108434
    [Abstract] [Full Text] [Related]

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