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Journal Abstract Search

146 related items for PubMed ID: 8531117

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  • 3. Possible role of free radical formation in clozapine (clozaril)-induced agranulocytosis.
    Fischer V, Haar JA, Greiner L, Lloyd RV, Mason RP.
    Mol Pharmacol; 1991 Nov; 40(5):846-53. PubMed ID: 1658615
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  • 4. Role of human glutathione S-transferases in the inactivation of reactive metabolites of clozapine.
    Dragovic S, Boerma JS, van Bergen L, Vermeulen NP, Commandeur JN.
    Chem Res Toxicol; 2010 Sep 20; 23(9):1467-76. PubMed ID: 20849150
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  • 5. A comparison of the covalent binding of clozapine, procainamide, and vesnarinone to human neutrophils in vitro and rat tissues in vitro and in vivo.
    Gardner I, Popović M, Zahid N, Uetrecht JP.
    Chem Res Toxicol; 2005 Sep 20; 18(9):1384-94. PubMed ID: 16167830
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  • 6. Clozapine is oxidized by activated human neutrophils to a reactive nitrenium ion that irreversibly binds to the cells.
    Liu ZC, Uetrecht JP.
    J Pharmacol Exp Ther; 1995 Dec 20; 275(3):1476-83. PubMed ID: 8531118
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  • 7. The cytotoxicity of clozapine metabolites: implications for predicting clozapine-induced agranulocytosis.
    Tschen AC, Rieder MJ, Oyewumi LK, Freeman DJ.
    Clin Pharmacol Ther; 1999 May 20; 65(5):526-32. PubMed ID: 10340918
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  • 8. Testing the hypothesis that selenium deficiency is a risk factor for clozapine-induced agranulocytosis in rats.
    Ip J, Uetrecht JP.
    Chem Res Toxicol; 2008 Apr 20; 21(4):874-8. PubMed ID: 18380444
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  • 10. Metabolism and bioactivation of clozapine by human liver in vitro.
    Pirmohamed M, Williams D, Madden S, Templeton E, Park BK.
    J Pharmacol Exp Ther; 1995 Mar 20; 272(3):984-90. PubMed ID: 7891353
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  • 11. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug 20; (59):1-66, A1-E7. PubMed ID: 11803702
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  • 12. Bioactivation of clozapine by murine cardiac tissue in vivo and in vitro.
    Williams DP, O'Donnell CJ, Maggs JL, Leeder JS, Uetrecht J, Pirmohamed M, Park BK.
    Chem Res Toxicol; 2003 Oct 20; 16(10):1359-64. PubMed ID: 14565776
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  • 13. Involvement of myeloperoxidase and NADPH oxidase in the covalent binding of amodiaquine and clozapine to neutrophils: implications for drug-induced agranulocytosis.
    Lobach AR, Uetrecht J.
    Chem Res Toxicol; 2014 Apr 21; 27(4):699-709. PubMed ID: 24588327
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