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PUBMED FOR HANDHELDS

Journal Abstract Search


116 related items for PubMed ID: 8534424

  • 1. Potential treatment of Alzheimer disease using cholinergic channel activators (ChCAs) with cognitive enhancement, anxiolytic-like, and cytoprotective properties.
    Arneric SP, Sullivan JP, Decker MW, Brioni JD, Bannon AW, Briggs CA, Donnelly-Roberts D, Radek RJ, Marsh KC, Kyncl J.
    Alzheimer Dis Assoc Disord; 1995; 9 Suppl 2():50-61. PubMed ID: 8534424
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  • 2. (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization.
    Decker MW, Brioni JD, Sullivan JP, Buckley MJ, Radek RJ, Raszkiewicz JL, Kang CH, Kim DJ, Giardina WJ, Wasicak JT.
    J Pharmacol Exp Ther; 1994 Jul; 270(1):319-28. PubMed ID: 7913497
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  • 4. Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist.
    Damaj MI, Creasy KR, Welch SP, Rosecrans JA, Aceto MD, Martin BR.
    Psychopharmacology (Berl); 1995 Aug; 120(4):483-90. PubMed ID: 8539331
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  • 5. Anxiolytic-like effects of the novel cholinergic channel activator ABT-418.
    Brioni JD, O'Neill AB, Kim DJ, Buckley MJ, Decker MW, Arneric SP.
    J Pharmacol Exp Ther; 1994 Oct; 271(1):353-61. PubMed ID: 7965735
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  • 6. Central nicotinic receptor agonists ABT-418, ABT-089, and (-)-nicotine reduce distractibility in adult monkeys.
    Prendergast MA, Jackson WJ, Terry AV, Decker MW, Arneric SP, Buccafusco JJ.
    Psychopharmacology (Berl); 1998 Mar; 136(1):50-8. PubMed ID: 9537682
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  • 7. ABT-418: discriminative stimulus properties and effect on ventral tegmental cell activity.
    Brioni JD, Kim DJ, Brodie MS, Decker MW, Arneric SP.
    Psychopharmacology (Berl); 1995 Jun; 119(4):368-75. PubMed ID: 7480515
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  • 8. Acute effects of the selective cholinergic channel activator (nicotinic agonist) ABT-418 in Alzheimer's disease.
    Potter A, Corwin J, Lang J, Piasecki M, Lenox R, Newhouse PA.
    Psychopharmacology (Berl); 1999 Mar; 142(4):334-42. PubMed ID: 10229057
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  • 10. In vitro neuroprotective properties of the novel cholinergic channel activator (ChCA), ABT-418.
    Donnelly-Roberts DL, Xue IC, Arneric SP, Sullivan JP.
    Brain Res; 1996 May 06; 719(1-2):36-44. PubMed ID: 8782861
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  • 11. ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys.
    Decker MW, Bannon AW, Curzon P, Gunther KL, Brioni JD, Holladay MW, Lin NH, Li Y, Daanen JF, Buccafusco JJ, Prendergast MA, Jackson WJ, Arneric SP.
    J Pharmacol Exp Ther; 1997 Oct 06; 283(1):247-58. PubMed ID: 9336330
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  • 12. Evidence for nicotinic receptors potentially modulating nociceptive transmission at the level of the primary sensory neuron: studies with F11 cells.
    Puttfarcken PS, Manelli AM, Arneric SP, Donnelly-Roberts DL.
    J Neurochem; 1997 Sep 06; 69(3):930-8. PubMed ID: 9282914
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  • 14. Cognitive enhancing properties and tolerability of cholinergic agents in mice: a comparative study of nicotine, donepezil, and SIB-1553A, a subtype-selective ligand for nicotinic acetylcholine receptors.
    Bontempi B, Whelan KT, Risbrough VB, Lloyd GK, Menzaghi F.
    Neuropsychopharmacology; 2003 Jul 06; 28(7):1235-46. PubMed ID: 12700710
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  • 15. Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.
    Lin NH, Gunn DE, Ryther KB, Garvey DS, Donnelly-Roberts DL, Decker MW, Brioni JD, Buckley MJ, Rodrigues AD, Marsh KG, Anderson DJ, Buccafusco JJ, Prendergast MA, Sullivan JP, Williams M, Arneric SP, Holladay MW.
    J Med Chem; 1997 Jan 31; 40(3):385-90. PubMed ID: 9022806
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  • 16. In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease.
    Bitner RS, Bunnelle WH, Decker MW, Drescher KU, Kohlhaas KL, Markosyan S, Marsh KC, Nikkel AL, Browman K, Radek R, Anderson DJ, Buccafusco J, Gopalakrishnan M.
    J Pharmacol Exp Ther; 2010 Sep 01; 334(3):875-86. PubMed ID: 20504913
    [Abstract] [Full Text] [Related]

  • 17. Ligands for brain cholinergic channel receptors: synthesis and in vitro characterization of novel isoxazoles and isothiazoles as bioisosteric replacements for the pyridine ring in nicotine.
    Garvey DS, Wasicak JT, Elliott RL, Lebold SA, Hettinger AM, Carrera GM, Lin NH, He Y, Holladay MW, Anderson DJ.
    J Med Chem; 1994 Dec 23; 37(26):4455-63. PubMed ID: 7799396
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  • 19. Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidine.
    Badio B, Garraffo HM, Plummer CV, Padgett WL, Daly JW.
    Eur J Pharmacol; 1997 Feb 26; 321(2):189-94. PubMed ID: 9063687
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