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Journal Abstract Search
116 related items for PubMed ID: 8534424
1. Potential treatment of Alzheimer disease using cholinergic channel activators (ChCAs) with cognitive enhancement, anxiolytic-like, and cytoprotective properties. Arneric SP, Sullivan JP, Decker MW, Brioni JD, Bannon AW, Briggs CA, Donnelly-Roberts D, Radek RJ, Marsh KC, Kyncl J. Alzheimer Dis Assoc Disord; 1995; 9 Suppl 2():50-61. PubMed ID: 8534424 [Abstract] [Full Text] [Related]
2. (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization. Decker MW, Brioni JD, Sullivan JP, Buckley MJ, Radek RJ, Raszkiewicz JL, Kang CH, Kim DJ, Giardina WJ, Wasicak JT. J Pharmacol Exp Ther; 1994 Jul; 270(1):319-28. PubMed ID: 7913497 [Abstract] [Full Text] [Related]
14. Cognitive enhancing properties and tolerability of cholinergic agents in mice: a comparative study of nicotine, donepezil, and SIB-1553A, a subtype-selective ligand for nicotinic acetylcholine receptors. Bontempi B, Whelan KT, Risbrough VB, Lloyd GK, Menzaghi F. Neuropsychopharmacology; 2003 Jul 06; 28(7):1235-46. PubMed ID: 12700710 [Abstract] [Full Text] [Related]
15. Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties. Lin NH, Gunn DE, Ryther KB, Garvey DS, Donnelly-Roberts DL, Decker MW, Brioni JD, Buckley MJ, Rodrigues AD, Marsh KG, Anderson DJ, Buccafusco JJ, Prendergast MA, Sullivan JP, Williams M, Arneric SP, Holladay MW. J Med Chem; 1997 Jan 31; 40(3):385-90. PubMed ID: 9022806 [Abstract] [Full Text] [Related]
16. In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease. Bitner RS, Bunnelle WH, Decker MW, Drescher KU, Kohlhaas KL, Markosyan S, Marsh KC, Nikkel AL, Browman K, Radek R, Anderson DJ, Buccafusco J, Gopalakrishnan M. J Pharmacol Exp Ther; 2010 Sep 01; 334(3):875-86. PubMed ID: 20504913 [Abstract] [Full Text] [Related]
17. Ligands for brain cholinergic channel receptors: synthesis and in vitro characterization of novel isoxazoles and isothiazoles as bioisosteric replacements for the pyridine ring in nicotine. Garvey DS, Wasicak JT, Elliott RL, Lebold SA, Hettinger AM, Carrera GM, Lin NH, He Y, Holladay MW, Anderson DJ. J Med Chem; 1994 Dec 23; 37(26):4455-63. PubMed ID: 7799396 [Abstract] [Full Text] [Related]