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271 related items for PubMed ID: 8534933

  • 1. Cytotoxic potential of monoalkylation products between mitomycins and DNA: studies of decarbamoyl mitomycin C in wild-type and repair-deficient cell lines.
    Kim SY, Rockwell S.
    Oncol Res; 1995; 7(5):39-47. PubMed ID: 8534933
    [Abstract] [Full Text] [Related]

  • 2. Cytotoxic potential of monoalkylation products between mitomycins and DNA: studies of decarbamoyl mitomycin C in wild-type and repair-deficient cell lines.
    Rockwell S, Kim SY.
    Oncol Res; 1995; 7(1):39-47. PubMed ID: 7549043
    [Abstract] [Full Text] [Related]

  • 3. Adducts of mitomycin C and DNA in EMT6 mouse mammary tumor cells: effects of hypoxia and dicumarol on adduct patterns.
    Bizanek R, Chowdary D, Arai H, Kasai M, Hughes CS, Sartorelli AC, Rockwell S, Tomasz M.
    Cancer Res; 1993 Nov 01; 53(21):5127-34. PubMed ID: 7693331
    [Abstract] [Full Text] [Related]

  • 4. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells.
    Fracasso PM, Sartorelli AC.
    Cancer Res; 1986 Aug 01; 46(8):3939-44. PubMed ID: 3089583
    [Abstract] [Full Text] [Related]

  • 5. Relative toxicities of DNA cross-links and monoadducts: new insights from studies of decarbamoyl mitomycin C and mitomycin C.
    Palom Y, Suresh Kumar G, Tang LQ, Paz MM, Musser SM, Rockwell S, Tomasz M.
    Chem Res Toxicol; 2002 Nov 01; 15(11):1398-406. PubMed ID: 12437330
    [Abstract] [Full Text] [Related]

  • 6. Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C.
    Palom Y, Belcourt MF, Kumar GS, Arai H, Kasai M, Sartorelli AC, Rockwell S, Tomasz M.
    Oncol Res; 1998 Nov 01; 10(10):509-21. PubMed ID: 10338154
    [Abstract] [Full Text] [Related]

  • 7. Modification of the metabolism and cytotoxicity of bioreductive alkylating agents by dicoumarol in aerobic and hypoxic murine tumor cells.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1989 Jun 15; 49(12):3310-3. PubMed ID: 2470504
    [Abstract] [Full Text] [Related]

  • 8. Effect of deficiencies in DNA repair on the toxicity of mitomycin C and porfiromycin to CHO cells under aerobic and hypoxic conditions.
    Hughes CS, Irvin CG, Rockwell S.
    Cancer Commun; 1991 Feb 15; 3(2):29-35. PubMed ID: 1899798
    [Abstract] [Full Text] [Related]

  • 9. Generation of reactive oxygen radicals through bioactivation of mitomycin antibiotics.
    Pritsos CA, Sartorelli AC.
    Cancer Res; 1986 Jul 15; 46(7):3528-32. PubMed ID: 3011250
    [Abstract] [Full Text] [Related]

  • 10. Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.
    Keyes SR, Fracasso PM, Heimbrook DC, Rockwell S, Sligar SG, Sartorelli AC.
    Cancer Res; 1984 Dec 15; 44(12 Pt 1):5638-43. PubMed ID: 6437671
    [Abstract] [Full Text] [Related]

  • 11. Mitomycin dimers: polyfunctional cross-linkers of DNA.
    Paz MM, Kumar GS, Glover M, Waring MJ, Tomasz M.
    J Med Chem; 2004 Jun 03; 47(12):3308-19. PubMed ID: 15163210
    [Abstract] [Full Text] [Related]

  • 12. Defective removal of DNA cross-links in a repair-deficient mutant of Chinese hamster cells.
    Meyn RE, Jenkins SF, Thompson LH.
    Cancer Res; 1982 Aug 03; 42(8):3106-10. PubMed ID: 6807537
    [Abstract] [Full Text] [Related]

  • 13. Effect of the superoxide dismutase inhibitor, diethyldithiocarbamate, on the cytotoxicity of mitomycin antibiotics.
    Pritsos CA, Keyes SR, Sartorelli AC.
    Cancer Biochem Biophys; 1989 Oct 03; 10(4):289-98. PubMed ID: 2559790
    [Abstract] [Full Text] [Related]

  • 14. Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells.
    Baumann RP, Hodnick WF, Seow HA, Belcourt MF, Rockwell S, Sherman DH, Sartorelli AC.
    Cancer Res; 2001 Nov 01; 61(21):7770-6. PubMed ID: 11691791
    [Abstract] [Full Text] [Related]

  • 15. Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry.
    Paz MM, Ladwa S, Champeil E, Liu Y, Rockwell S, Boamah EK, Bargonetti J, Callahan J, Roach J, Tomasz M.
    Chem Res Toxicol; 2008 Dec 01; 21(12):2370-8. PubMed ID: 19053323
    [Abstract] [Full Text] [Related]

  • 16. Structural and function modification of DNA by mitomycin C. Mechanism of the DNA sequence specificity of mitomycins.
    Gargiulo D, Kumar GS, Musser SS, Tomasz M.
    Nucleic Acids Symp Ser; 1995 Dec 01; (34):169-70. PubMed ID: 8841606
    [Abstract] [Full Text] [Related]

  • 17. Enhancement of mitomycin C cytotoxicity to hypoxic tumor cells by dicoumarol in vivo and in vitro.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1985 Jan 01; 45(1):213-6. PubMed ID: 2578093
    [Abstract] [Full Text] [Related]

  • 18. Cytotoxicity of BMS-181174. Effects of hypoxia, dicoumarol, and repair deficits.
    Rockwell S, Kemple B, Kelley M.
    Biochem Pharmacol; 1995 Oct 12; 50(8):1239-43. PubMed ID: 7488240
    [Abstract] [Full Text] [Related]

  • 19. Modification of the cytotoxic activity of mitomycin C by oxygen and ascorbic acid in Chinese hamster ovary cells and a repair-deficient mutant.
    Marshall RS, Rauth AM.
    Cancer Res; 1986 Jun 12; 46(6):2709-13. PubMed ID: 3084075
    [Abstract] [Full Text] [Related]

  • 20. Nuclear localization of NADPH:cytochrome c (P450) reductase enhances the cytotoxicity of mitomycin C to Chinese hamster ovary cells.
    Seow HA, Belcourt MF, Penketh PG, Hodnick WF, Tomasz M, Rockwell S, Sartorelli AC.
    Mol Pharmacol; 2005 Feb 12; 67(2):417-23. PubMed ID: 15547247
    [Abstract] [Full Text] [Related]


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