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Journal Abstract Search

123 related items for PubMed ID: 8544176

  • 1. Identification, characterization and pharmacological profile of three metabolites of (R)-(+)-1,2,3,6-tetrahydro-4-phenyl-1-[(3-phenylcyclohexen-1- yl)methyl]pyridine (CI-1007), a dopamine autoreceptor agonist and potential antipsychotic agent.
    Wright JL, Downing DM, Feng MR, Hayes RN, Heffner TG, MacKenzie RG, Meltzer LT, Pugsley TA, Wise LD.
    J Med Chem; 1995 Dec 22; 38(26):5007-14. PubMed ID: 8544176
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  • 2. The discovery and structure-activity relationships of 1,2,3,6-tetrahydro-4-phenyl-1-[(arylcyclohexenyl)alkyl]pyridines. Dopamine autoreceptor agonists and potential antipsychotic agents.
    Wright JL, Caprathe BW, Downing DM, Glase SA, Heffner TG, Jaen JC, Johnson SJ, Kesten SR, MacKenzie RG, Meltzer LT.
    J Med Chem; 1994 Oct 14; 37(21):3523-33. PubMed ID: 7932581
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  • 3. CI-1007, a dopamine partial agonist and potential antipsychotic agent. II. Neurophysiological and behavioral effects.
    Meltzer LT, Christoffersen CL, Corbin AE, Ninteman FW, Serpa KA, Wiley JN, Wise LD, Heffner TG.
    J Pharmacol Exp Ther; 1995 Aug 14; 274(2):912-20. PubMed ID: 7636754
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  • 8. Aryl 1-but-3-ynyl-4-phenyl-1,2,3,6-tetrahydropyridines as potential antipsychotic agents: synthesis and structure-activity relationships.
    Glase SA, Akunne HC, Heffner TG, Jaen JC, MacKenzie RG, Meltzer LT, Pugsley TA, Smith SJ, Wise LD.
    J Med Chem; 1996 Aug 02; 39(16):3179-87. PubMed ID: 8759640
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  • 9. Brain extracellular levels of the putative antipsychotic CI-1007 and its effects on striatal and nucleus accumbens dopamine overflow in the awake rat.
    Iyer RN, Davis MD, Juneau PL, Giordani AB.
    J Pharm Pharmacol; 1998 Oct 02; 50(10):1147-53. PubMed ID: 9821662
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  • 11. Pharmacological characterization of PD 118717, a putative piperazinyl benzopyranone dopamine autoreceptor agonist.
    Pugsley TA, Christofferson CL, Corbin A, DeWald HA, Demattos S, Meltzer LT, Myers SL, Shih YH, Whetzel SZ, Wiley JN.
    J Pharmacol Exp Ther; 1992 Dec 02; 263(3):1147-58. PubMed ID: 1361570
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  • 13. Dopamine autoreceptor agonists as potential antipsychotics. 3.6-Propyl-4,5,5a,6,7,8-hexahydrothiazolo[4,5-f]quinolin-2-amine.
    Caprathe BW, Jaen JC, Wise LD, Heffner TG, Pugsley TA, Meltzer LT, Parvez M.
    J Med Chem; 1991 Sep 02; 34(9):2736-46. PubMed ID: 1680195
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  • 16. (5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)(2-fluorophenyl)methanones . A series of novel potential antipsychotic agents.
    Wise LD, Butler DE, DeWald HA, Lustgarten D, Coughenour LL, Downs DA, Heffner TG, Pugsley TA.
    J Med Chem; 1986 Sep 02; 29(9):1628-37. PubMed ID: 2875184
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  • 17. Examination of a series of 8-[3-[bis(4-fluorophenyl)amino]propyl]-1-aryl-1,3,8- triazaspiro[4.5]decan-4-ones as potential antipsychotic agents.
    Wise LD, Pattison IC, Butler DE, DeWald HA, Lewis EP, Lobbestael SJ, Tecle H, Coughenour LL, Downs DA, Poschel BP.
    J Med Chem; 1985 Dec 02; 28(12):1811-7. PubMed ID: 2866248
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  • 18. ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease.
    Shiosaki K, Jenner P, Asin KE, Britton DR, Lin CW, Michaelides M, Smith L, Bianchi B, Didomenico S, Hodges L, Hong Y, Mahan L, Mikusa J, Miller T, Nikkel A, Stashko M, Witte D, Williams M.
    J Pharmacol Exp Ther; 1996 Jan 02; 276(1):150-60. PubMed ID: 8558425
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  • 19. 1,3-Dialkyl-4-(iminoarylmethyl)-1H-pyrazol-5-ols. A series of novel potential antipsychotic agents.
    Wise LD, Butler DE, DeWald HA, Lustgarten DM, Pattison IC, Schweiss DN, Coughenour LL, Downs DA, Heffner TG, Pugsley TA.
    J Med Chem; 1987 Oct 02; 30(10):1807-12. PubMed ID: 2888897
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