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Journal Abstract Search

423 related items for PubMed ID: 8546693

  • 1. Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells.
    Schuppin GT, Rhodes CJ.
    Biochem J; 1996 Jan 01; 313 ( Pt 1)(Pt 1):259-68. PubMed ID: 8546693
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  • 5. The biosynthesis of the subtilisin-related proprotein convertase PC3, but no that of the PC2 convertase, is regulated by glucose in parallel to proinsulin biosynthesis in rat pancreatic islets.
    Alarcón C, Lincoln B, Rhodes CJ.
    J Biol Chem; 1993 Feb 25; 268(6):4276-80. PubMed ID: 8440711
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  • 7. Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin.
    Wicksteed B, Alarcon C, Briaud I, Lingohr MK, Rhodes CJ.
    J Biol Chem; 2003 Oct 24; 278(43):42080-90. PubMed ID: 12928442
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  • 8. Maintained PC1 and PC2 expression in the AtT-20 variant cell line 6T3 lacking regulated secretion and POMC: restored POMC expression and regulated secretion after cAMP treatment.
    Day R, Benjannet S, Matsuuchi L, Kelly RB, Marcinkiewicz M, Chrétien M, Seidah NG.
    DNA Cell Biol; 1995 Feb 24; 14(2):175-88. PubMed ID: 7865135
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  • 9. Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2.
    Furuta M, Carroll R, Martin S, Swift HH, Ravazzola M, Orci L, Steiner DF.
    J Biol Chem; 1998 Feb 06; 273(6):3431-7. PubMed ID: 9452465
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  • 11. Effects of aging on insulin synthesis and secretion. Differential effects on preproinsulin messenger RNA levels, proinsulin biosynthesis, and secretion of newly made and preformed insulin in the rat.
    Wang SY, Halban PA, Rowe JW.
    J Clin Invest; 1988 Jan 06; 81(1):176-84. PubMed ID: 3275693
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  • 12. Levels of the conversion endoproteases PC1 (PC3) and PC2 distinguish between insulin-producing pancreatic islet beta cells and non-beta cells.
    Neerman-Arbez M, Cirulli V, Halban PA.
    Biochem J; 1994 May 15; 300 ( Pt 1)(Pt 1):57-61. PubMed ID: 8198551
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  • 13. Proinsulin processing in the rat insulinoma cell line INS after overexpression of the endoproteases PC2 or PC3 by recombinant adenovirus.
    Irminger JC, Meyer K, Halban P.
    Biochem J; 1996 Nov 15; 320 ( Pt 1)(Pt 1):11-5. PubMed ID: 8947461
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  • 14. Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats.
    Nie Y, Nakashima M, Brubaker PL, Li QL, Perfetti R, Jansen E, Zambre Y, Pipeleers D, Friedman TC.
    J Clin Invest; 2000 Apr 15; 105(7):955-65. PubMed ID: 10749575
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  • 15. Expression patterns of messenger ribonucleic acids encoding prohormone convertases (PC2 and PC3) in human pituitary adenomas.
    Hashimoto K, Koga M, Kouhara H, Arita N, Hayakawa T, Kishimoto T, Sato B.
    Clin Endocrinol (Oxf); 1994 Aug 15; 41(2):185-91. PubMed ID: 7923822
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  • 16. Glucose-induced preproinsulin gene expression is inhibited by the free fatty acid palmitate.
    Ritz-Laser B, Meda P, Constant I, Klages N, Charollais A, Morales A, Magnan C, Ktorza A, Philippe J.
    Endocrinology; 1999 Sep 15; 140(9):4005-14. PubMed ID: 10465270
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  • 17. Age-related impairment in the short term regulation of insulin biosynthesis by glucose in rat pancreatic islets.
    Wang SY, Rowe JW.
    Endocrinology; 1988 Aug 15; 123(2):1008-13. PubMed ID: 2456199
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  • 18. The role of prohormone convertases in insulin biosynthesis: evidence for inherited defects in their action in man and experimental animals.
    Steiner DF, Rouillé Y, Gong Q, Martin S, Carroll R, Chan SJ.
    Diabetes Metab; 1996 Apr 15; 22(2):94-104. PubMed ID: 8792089
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  • 19. Expression of the insulin gene: regulation by glucose, hydrocortisone and growth hormone in mouse pancreatic islets in organ culture.
    Brunstedt J.
    Acta Biol Med Ger; 1982 Apr 15; 41(12):1151-5. PubMed ID: 6765158
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  • 20. Processing of synthetic pro-islet amyloid polypeptide (proIAPP) 'amylin' by recombinant prohormone convertase enzymes, PC2 and PC3, in vitro.
    Higham CE, Hull RL, Lawrie L, Shennan KI, Morris JF, Birch NP, Docherty K, Clark A.
    Eur J Biochem; 2000 Aug 15; 267(16):4998-5004. PubMed ID: 10931181
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