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200 related items for PubMed ID: 8548781

  • 1. Functional expression of human topoisomerase II alpha in yeast: mutations at amino acids 450 or 803 of topoisomerase II alpha result in enzymes that can confer resistance to anti-topoisomerase II agents.
    Hsiung Y, Jannatipour M, Rose A, McMahon J, Duncan D, Nitiss JL.
    Cancer Res; 1996 Jan 01; 56(1):91-9. PubMed ID: 8548781
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  • 2. Mutations in the gyrB domain of eukaryotic topoisomerase II can lead to partially dominant resistance to etoposide and amsacrine.
    Nitiss JL, Vilalta PM, Wu H, McMahon J.
    Mol Pharmacol; 1994 Oct 01; 46(4):773-7. PubMed ID: 7969059
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  • 3. Yeast topoisomerase II mutants resistant to anti-topoisomerase agents: identification and characterization of new yeast topoisomerase II mutants selected for resistance to etoposide.
    Liu YX, Hsiung Y, Jannatipour M, Yeh Y, Nitiss JL.
    Cancer Res; 1994 Jun 01; 54(11):2943-51. PubMed ID: 8187080
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  • 4. Analysis of yeast DNA topoisomerase II mutants resistant to the antitumor drug amsacrine.
    Wasserman RA, Wang JC.
    Cancer Res; 1994 Apr 01; 54(7):1795-800. PubMed ID: 8137294
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  • 5. Chinese hamster ovary cells resistant to the topoisomerase II catalytic inhibitor ICRF-159: a Tyr49Phe mutation confers high-level resistance to bisdioxopiperazines.
    Sehested M, Wessel I, Jensen LH, Holm B, Oliveri RS, Kenwrick S, Creighton AM, Nitiss JL, Jensen PB.
    Cancer Res; 1998 Apr 01; 58(7):1460-8. PubMed ID: 9537249
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  • 13. The top2-5 mutant of yeast topoisomerase II encodes an enzyme resistant to etoposide and amsacrine.
    Jannatipour M, Liu YX, Nitiss JL.
    J Biol Chem; 1993 Sep 05; 268(25):18586-92. PubMed ID: 8395511
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  • 14. Mutations at arg486 and glu571 in human topoisomerase IIalpha confer resistance to amsacrine: relevance for antitumor drug resistance in human cells.
    Patel S, Keller BA, Fisher LM.
    Mol Pharmacol; 2000 Apr 05; 57(4):784-91. PubMed ID: 10727526
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  • 15. Single-strand conformational polymorphism analysis of the M(r) 170,000 isozyme of DNA topoisomerase II in human tumor cells.
    Danks MK, Warmoth MR, Friche E, Granzen B, Bugg BY, Harker WG, Zwelling LA, Futscher BW, Suttle DP, Beck WT.
    Cancer Res; 1993 Mar 15; 53(6):1373-9. PubMed ID: 8383009
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  • 16. Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II.
    Nitiss JL, Liu YX, Harbury P, Jannatipour M, Wasserman R, Wang JC.
    Cancer Res; 1992 Aug 15; 52(16):4467-72. PubMed ID: 1322791
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  • 17. Mutation E522K in human DNA topoisomerase IIbeta confers resistance to methyl N-(4'-(9-acridinylamino)-phenyl)carbamate hydrochloride and methyl N-(4'-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide but hypersensitivity to etoposide.
    Leontiou C, Lakey JH, Austin CA.
    Mol Pharmacol; 2004 Sep 15; 66(3):430-9. PubMed ID: 15322234
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  • 19. The bis(naphthalimide) DMP-840 causes cytotoxicity by its action against eukaryotic topoisomerase II.
    Nitiss JL, Zhou J, Rose A, Hsiung Y, Gale KC, Osheroff N.
    Biochemistry; 1998 Mar 03; 37(9):3078-85. PubMed ID: 9485461
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