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Journal Abstract Search

186 related items for PubMed ID: 8558511

  • 1. Characterizations of the unusual dissociation properties of melanotropin peptides from the melanocortin receptor, hMC1R.
    Haskell-Luevano C, Miwa H, Dickinson C, Hadley ME, Hruby VJ, Yamada T, Gantz I.
    J Med Chem; 1996 Jan 19; 39(2):432-5. PubMed ID: 8558511
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  • 2. Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors.
    Haskell-Luevano C, Nikiforovich G, Sharma SD, Yang YK, Dickinson C, Hruby VJ, Gantz I.
    J Med Chem; 1997 May 23; 40(11):1738-48. PubMed ID: 9171884
    [Abstract] [Full Text] [Related]

  • 3. Three-dimensional molecular models of the hMC1R melanocortin receptor: complexes with melanotropin peptide agonists.
    Haskell-Luevano C, Sawyer TK, Trumpp-Kallmeyer S, Bikker JA, Humblet C, Gantz I, Hruby VJ.
    Drug Des Discov; 1996 Dec 23; 14(3):197-211. PubMed ID: 9017363
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  • 4. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.
    Hruby VJ, Lu D, Sharma SD, Castrucci AL, Kesterson RA, al-Obeidi FA, Hadley ME, Cone RD.
    J Med Chem; 1995 Sep 01; 38(18):3454-61. PubMed ID: 7658432
    [Abstract] [Full Text] [Related]

  • 5. Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R.
    Haskell-Luevano C, Hendrata S, North C, Sawyer TK, Hadley ME, Hruby VJ, Dickinson C, Gantz I.
    J Med Chem; 1997 Jul 04; 40(14):2133-9. PubMed ID: 9216831
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  • 6. Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics.
    Al-Obeidi F, Castrucci AM, Hadley ME, Hruby VJ.
    J Med Chem; 1989 Dec 04; 32(12):2555-61. PubMed ID: 2555512
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  • 8. Discovery and structure-activity relationships of novel alpha-melanocyte-stimulating hormone inhibitors.
    Sawyer TK, Staples DJ, Castrucci AM, Hadley ME.
    Pept Res; 1989 Dec 04; 2(1):140-6. PubMed ID: 2562482
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  • 9. Binding and cAMP studies of melanotropin peptides with the cloned human peripheral melanocortin receptor, hMC1R.
    Haskell-Luevano C, Miwa H, Dickinson C, Hruby VJ, Yamada T, Gantz I.
    Biochem Biophys Res Commun; 1994 Nov 15; 204(3):1137-42. PubMed ID: 7980588
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  • 12. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA, Doufexis M, Kapas S, Chhajlani V.
    Biochem Biophys Res Commun; 2001 Mar 09; 281(4):851-7. PubMed ID: 11237737
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  • 14. Topographical modification of melanotropin peptide analogues with beta-methyltryptophan isomers at position 9 leads to differential potencies and prolonged biological activities.
    Haskell-Luevano C, Boteju LW, Miwa H, Dickinson C, Gantz I, Yamada T, Hadley ME, Hruby VJ.
    J Med Chem; 1995 Nov 10; 38(23):4720-9. PubMed ID: 7473600
    [Abstract] [Full Text] [Related]

  • 15. Design of novel chimeric melanotropin-deltorphin analogues. Discovery of the first potent human melanocortin 1 receptor antagonist.
    Han G, Quillan JM, Carlson K, Sadée W, Hruby VJ.
    J Med Chem; 2003 Feb 27; 46(5):810-9. PubMed ID: 12593660
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  • 16. Comparative biological activities of potent analogues of alpha-melanotropin. Effect of nonaromatic and para substituted aromatic amino acids at position 7.
    Wilkes BC, Cody WL, Hruby VJ, Castrucci AM, Hadley ME.
    Int J Pept Protein Res; 1986 Jun 27; 27(6):685-94. PubMed ID: 3489682
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  • 18. Comparative biological activities of alpha-MSH antagonists in vertebrate pigment cells.
    Castrucci AM, Almeida AL, al-Obeidi FA, Hadley ME, Hruby VJ, Staples DJ, Sawyer TK.
    Gen Comp Endocrinol; 1997 Mar 27; 105(3):410-6. PubMed ID: 9073503
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  • 19. New melanocortin 1 receptor binding motif based on the C-terminal sequence of alpha-melanocyte-stimulating hormone.
    Schiöth HB, Muceniece R, Mutule I, Wikberg JE.
    Basic Clin Pharmacol Toxicol; 2006 Oct 27; 99(4):287-93. PubMed ID: 17040213
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  • 20. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A, Wang XS, Joseph CG, Xiang Z, Bauzo RM, Scott JW, Sorensen NB, Shaw AM, Millard WJ, Richards NG, Haskell-Luevano C.
    J Med Chem; 2004 Apr 22; 47(9):2194-207. PubMed ID: 15084118
    [Abstract] [Full Text] [Related]

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