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109 related items for PubMed ID: 8558535
1. Analogues of 10-deazaaminopterin and 5-alkyl-5,10-dideazaaminopterin with the 4-substituted 1-naphthoyl group in the place of 4-substituted benzoyl. Piper JR, Ramamurthy B, Johnson CA, Otter GM, Sirotnak FM. J Med Chem; 1996 Jan 19; 39(2):614-8. PubMed ID: 8558535 [Abstract] [Full Text] [Related]
5. Synthesis and antifolate evaluation of the 10-propargyl derivatives of 5-deazafolic acid, 5-deazaaminopterin, and 5-methyl-5-deazaaminopterin. Piper JR, Malik ND, Rhee MS, Galivan J, Sirotnak FM. J Med Chem; 1992 Jan 24; 35(2):332-7. PubMed ID: 1732551 [Abstract] [Full Text] [Related]
6. Synthesis and potent antifolate activity and cytotoxicity of B-ring deaza analogues of the nonpolyglutamatable dihydrofolate reductase inhibitor Nalpha-(4-amino-4-deoxypteroyl)-Ndelta-hemiphthaloyl- L-ornithine (PT523). Rosowsky A, Wright JE, Vaidya CM, Bader H, Forsch RA, Mota CE, Pardo J, Chen CS, Chen YN. J Med Chem; 1998 Dec 17; 41(26):5310-9. PubMed ID: 9857098 [Abstract] [Full Text] [Related]
9. Studies on analogues of classical antifolates bearing the naphthoyl group in place of benzoyl in the side chain. Piper JR, Johnson CA, Maddry JA, Malik ND, McGuire JJ, Otter GM, Sirotnak FM. J Med Chem; 1993 Dec 24; 36(26):4161-71. PubMed ID: 8277497 [Abstract] [Full Text] [Related]
10. Analogues of methotrexate in rheumatoid arthritis. 1. Effects of 10-deazaaminopterin analogues on type II collagen-induced arthritis in mice. DeGraw JI, Colwell WT, Crase J, Smith RL, Piper JR, Waud WR, Sirotnak FM. J Med Chem; 1997 Jan 31; 40(3):370-6. PubMed ID: 9022804 [Abstract] [Full Text] [Related]
11. Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro. Samuels LL, Moccio DM, Sirotnak FM. Cancer Res; 1985 Apr 31; 45(4):1488-95. PubMed ID: 3978616 [Abstract] [Full Text] [Related]
13. Differing specificities for 4-aminofolate analogues of folylpolyglutamyl synthetase from tumors and proliferative intestinal epithelium of the mouse with significance for selective antitumor action. Rumberger BG, Barrueco JR, Sirotnak FM. Cancer Res; 1990 Aug 01; 50(15):4639-43. PubMed ID: 2369741 [Abstract] [Full Text] [Related]
15. Inhibitory action of 10-deazaaminopterins and their polyglutamates on human thymidylate synthase. Ueda T, Dutschman GE, Nair MG, Degraw JI, Sirotnak FM, Cheng YC. Mol Pharmacol; 1986 Aug 01; 30(2):149-53. PubMed ID: 2426568 [Abstract] [Full Text] [Related]
16. Synthesis and antifolate properties of 10-alkyl-8,10-dideazaminopterins. DeGraw JI, Christie PH, Brown EG, Kelly LF, Kisliuk RL, Gaumont Y, Sirotnak FM. J Med Chem; 1984 Mar 01; 27(3):376-80. PubMed ID: 6699882 [Abstract] [Full Text] [Related]
18. Methotrexate analogues. 31. Meta and ortho isomers of aminopterin, compounds with a double bond in the side chain, and a novel analogue modified at the alpha-carbon: chemical and in vitro biological studies. Rosowsky A, Bader H, Forsch RA, Moran RG, Freisheim JH. J Med Chem; 1988 Apr 01; 31(4):763-8. PubMed ID: 3351853 [Abstract] [Full Text] [Related]
19. Synthesis and antifolate properties of 10-alkyl-5,10-dideaza analogues of methotrexate and tetrahydrofolic acid. DeGraw JI, Christie PH, Kisliuk RL, Gaumont Y, Sirotnak FM. J Med Chem; 1990 Feb 01; 33(2):673-7. PubMed ID: 2299633 [Abstract] [Full Text] [Related]