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Journal Abstract Search


150 related items for PubMed ID: 8564410

  • 1. Syntheses, activity and modeling studies of 3- and 4-(sulfo- and sulfonamidoalkyl)pyridine and piperidine-2-carboxylic acid derivatives as analogs of NMDA receptor antagonists.
    el Hadri A, Maldivi P, Leclerc G, Rocher JP.
    Bioorg Med Chem; 1995 Sep; 3(9):1183-201. PubMed ID: 8564410
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and pharmacology of a series of 3- and 4-(phosphonoalkyl)pyridine- and -piperidine-2-carboxylic acids. Potent N-methyl-D-aspartate receptor antagonists.
    Ornstein PL, Schaus JM, Chambers JW, Huser DL, Leander JD, Wong DT, Paschal JW, Jones ND, Deeter JB.
    J Med Chem; 1989 Apr; 32(4):827-33. PubMed ID: 2539478
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  • 3. Structure-activity studies of 6-(tetrazolylalkyl)-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 1. Effects of stereochemistry, chain length, and chain substitution.
    Ornstein PL, Arnold MB, Allen NK, Bleisch T, Borromeo PS, Lugar CW, Leander JD, Lodge D, Schoepp DD.
    J Med Chem; 1996 May 24; 39(11):2219-31. PubMed ID: 8667365
    [Abstract] [Full Text] [Related]

  • 4. Structure-activity analysis of binding kinetics for NMDA receptor competitive antagonists: the influence of conformational restriction.
    Benveniste M, Mayer ML.
    Br J Pharmacol; 1991 Sep 24; 104(1):207-21. PubMed ID: 1686203
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  • 5. 4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action.
    Ornstein PL, Schoepp DD, Arnold MB, Leander JD, Lodge D, Paschal JW, Elzey T.
    J Med Chem; 1991 Jan 24; 34(1):90-7. PubMed ID: 1825117
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  • 8. Structure-activity relationships of competitive NMDA receptor antagonists.
    Cheung NS, O'Callaghan D, Ryan MC, Dutton R, Wong MG, Beart PM.
    Eur J Pharmacol; 1996 Oct 10; 313(1-2):159-62. PubMed ID: 8905343
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  • 10. Synthesis of N-substituted 4-(4-hydroxyphenyl)piperidines, 4-(4-hydroxybenzyl)piperidines, and (+/-)-3-(4-hydroxyphenyl)pyrrolidines: selective antagonists at the 1A/2B NMDA receptor subtype.
    Guzikowski AP, Tamiz AP, Acosta-Burruel M, Hong-Bae S, Cai SX, Hawkinson JE, Keana JF, Kesten SR, Shipp CT, Tran M, Whittemore ER, Woodward RM, Wright JL, Zhou ZL.
    J Med Chem; 2000 Mar 09; 43(5):984-94. PubMed ID: 10715162
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  • 11. 4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: a novel, potent, and selective NR1/2B NMDA receptor antagonist.
    Zhou ZL, Cai SX, Whittemore ER, Konkoy CS, Espitia SA, Tran M, Rock DM, Coughenour LL, Hawkinson JE, Boxer PA, Bigge CF, Wise LD, Weber E, Woodward RM, Keana JF.
    J Med Chem; 1999 Jul 29; 42(15):2993-3000. PubMed ID: 10425109
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  • 12. Characterization of the binding of [3H]-CGS 19755: a novel N-methyl-D-aspartate antagonist with nanomolar affinity in rat brain.
    Murphy DE, Hutchison AJ, Hurt SD, Williams M, Sills MA.
    Br J Pharmacol; 1988 Nov 29; 95(3):932-8. PubMed ID: 2850065
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  • 13. Synthesis of 1,4,7,8,9,10-hexahydro-9-methyl-6-nitropyrido[3,4-f]- quinoxaline-2,3-dione and related quinoxalinediones: characterization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (and N-methyl-D-aspartate) receptor and anticonvulsant activity.
    Bigge CF, Malone TC, Boxer PA, Nelson CB, Ortwine DF, Schelkun RM, Retz DM, Lescosky LJ, Borosky SA, Vartanian MG.
    J Med Chem; 1995 Sep 15; 38(19):3720-40. PubMed ID: 7562904
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  • 14. Potent, orally active, competitive N-methyl-D-aspartate (NMDA) receptor antagonists are substrates for a neutral amino acid uptake system in Chinese hamster ovary cells.
    Li JH, Bigge CF, Williamson RM, Borosky SA, Vartanian MG, Ortwine DF.
    J Med Chem; 1995 May 26; 38(11):1955-65. PubMed ID: 7783127
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  • 15. Structure-activity studies of 6-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 2. Effects of distal acid bioisosteric substitution, absolute stereochemical preferences, and in vivo activity.
    Ornstein PL, Arnold MB, Allen NK, Bleisch T, Borromeo PS, Lugar CW, Leander JD, Lodge D, Schoepp DD.
    J Med Chem; 1996 May 24; 39(11):2232-44. PubMed ID: 8667366
    [Abstract] [Full Text] [Related]

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  • 18. Structure-activity analysis of a novel NR2C/NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl) piperazine-2,3-dicarboxylic acid.
    Feng B, Tse HW, Skifter DA, Morley R, Jane DE, Monaghan DT.
    Br J Pharmacol; 2004 Feb 24; 141(3):508-16. PubMed ID: 14718249
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  • 19. Synthesis and resolution of racemic eliprodil and evaluation of the enantiomers of eliprodil as NMDA receptor antagonists.
    Pabel J, Höfner G, Wanner KT.
    Bioorg Med Chem Lett; 2000 Jun 19; 10(12):1377-80. PubMed ID: 10890168
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  • 20. Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(arylalkynyl)-4-benzylpiperidines.
    Wright JL, Gregory TF, Bigge CF, Boxer PA, Serpa K, Meltzer LT, Wise LD, Cai SX, Hawkinson JE, Konkoy CS, Whittemore ER, Woodward RM, Zhou ZL.
    J Med Chem; 1999 Jul 01; 42(13):2469-77. PubMed ID: 10395488
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